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4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2
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ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXT4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2John J. Talley, David L. Brown, Jeffery S. Carter, Matthew J. Graneto, Carol M. Koboldt, Jaime L. Masferrer, William E. Perkins, Roland S. Rogers, Alexander F. Shaffer, Yan Y. Zhang, Ben S. Zweifel, and Karen SeibertView Author Information Searle Research and Development, 700 Chesterfield Parkway, St. Louis, Missouri 63198, and 4901 Searle Parkway, Skokie, Illinois 60077 Cite this: J. Med. Chem. 2000, 43, 5, 775–777Publication Date (Web):February 23, 2000Publication History Received17 November 1999Published online23 February 2000Published inissue 1 March 2000https://pubs.acs.org/doi/10.1021/jm990577vhttps://doi.org/10.1021/jm990577vrapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views2297Altmetric-Citations527LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Antiinflammatories,Assays,Inflammation,Inhibitors,Peptides and proteins Get e-Alerts
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Citations
Cites
Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.
Masferrer, J. L., Zweifel, B. S., Manning, P. T., Hauser, S. D., Leahy, K. M., Smith, W. G., Isakson, P. C., & Seibert, K. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.8.3228 · Cited by 1,310
Self-citation
Cited by
The Methylation Effect in Medicinal Chemistry
Barreiro, E. J., Kümmerle, A. E., & Fraga, C. A. M. (2011) · Chemical Reviews · doi:10.1021/cr200060g · Cited by 1,017
Rao, P., & Knaus, E. E. (2008) · Journal of Pharmacy & Pharmaceutical Sciences · doi:10.18433/j3t886 · Cited by 773
Myint, K.-Z., Wang, L., Tong, Q., & Xie, X.-Q. (2012) · Molecular Pharmaceutics · doi:10.1021/mp300237z · Cited by 139
Myint, K. Z., & Xie, X.-Q. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-2239-0_9 · Cited by 21
Metadata
- Authors
- Talley, J. J., Brown, D. L., Carter, J. S., Graneto, M. J., Koboldt, C. M., Masferrer, J. L., Perkins, W. E., Rogers, R. S., Shaffer, A. F., Zhang, Y. Y., Zweifel, B. S., & Seibert, K.
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2000-02-23
- Volume
- 43
- Issue
- 5
- Pages
- 775-777
- ISSN
- 0022-2623 (ISSN-L)
- 1520-4804
- OpenAlex
- W2078736915
- Cited by
- 638
- References
- 1
- FWCI
- 17.96
- Type
- journal article
- Language
- en
- Open access
- green
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