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Cited by 328

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Protein Detection and Quantitation by Tetraphenylethene-Based Fluorescent Probes with Aggregation-Induced Emission Characteristics

Tong, Hui, Hong, Yuning, Dong, Yongqiang, Häussler, Matthias, Li, Zhen, Lam, Jacky W. Y., Dong, Yuping, Sung, Herman H.-Y., Williams, Ian D., Tang, Ben Zhong·2007·The Journal of Physical Chemistry B

Abstract

Three functionalized derivatives of tetraphenylethylene (TPE), namely, 1,2-bis(4-methoxyphenyl)-1,2-diphenylethene (1), 1,2-bis(4-hydroxyphenyl)-1,2-diphenylethene (2), and 1,2-bis[4-(3-sulfonatopropoxyl)phenyl]-1,2-diphenylethene sodium salt (3), were synthesized and their fluorescence properties were investigated. All the TPE molecules are nonluminescent in the solution state but are induced to emit efficiently by aggregate formation. This novel process of aggregation-induced emission (AIE) is rationalized to be caused by the restriction of intramolecular rotations of the dye molecules in the aggregate state. The possibility of utilizing the AIE effect for protein detection and quantification is explored using bovine serum albumin (BSA) as a model protein, with salt 3 being found to perform as a stable, sensitive, and selective bioprobe.

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Metadata

Authors
Tong, H., Hong, Y., Dong, Y., Häussler, M., Li, Z., Lam, J. W. Y., Dong, Y., Sung, H. H.-Y., Williams, I. D., & Tang, B. Z.
Venue
The Journal of Physical Chemistry B
Published
2007-09-18
Volume
111
Issue
40
Pages
11817-11823
ISSN
  • 1520-5207 (ISSN-L)
  • 1520-6106
OpenAlex
W2041390593
Cited by
328
References
1
FWCI
9.87
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Protein Detection and Quantitation by Tetraphenylethene-Based Fluorescent Probes with Aggregation-Induced Emission Characteristics. https://app.cochat.ai/papers/10.1021/jp073147m
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Tong, H., Hong, Y., Dong, Y., Häussler, M., Li, Z., Lam, J. W. Y., Dong, Y., Sung, H. H.-Y., Williams, I. D., & Tang, B. Z. (2007). Protein Detection and Quantitation by Tetraphenylethene-Based Fluorescent Probes with Aggregation-Induced Emission Characteristics. The Journal of Physical Chemistry B. https://doi.org/10.1021/jp073147m

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