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Multicolor In Vivo Imaging of Upconversion Nanoparticles with Emissions Tuned by Luminescence Resonance Energy Transfer
Abstract
Upconversion nanoparticles (UCNPs) based on sodium yttrium fluoride (NaYF 4 ) nanocrystals are synthesized, functionalized with an amphiphilic polymer, and loaded with fluorescent and quenching molecules by physical adsorption. The formed supramolecular UCNP−dye complexes show tuned visible emission spectra owing to the luminescence resonance energy transfer (LRET) from nanoparticles to the organic dyes under near-infrared (NIR) excitation, and can be well separated in multicolor imaging after spectral decovolution. Our work provides a facile and flexible method to modulate the upconversion luminescence (UCL) spectra of UCNPs for in vivo multicolor UCL imaging in animals.
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Cited by
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
Chen, G., Qiu, H., Prasad, P. N., & Chen, X. (2014) · Chemical Reviews · doi:10.1021/cr400425h · Cited by 2,699
Zheng, W., Huang, P., Tu, D., Ma, E., Zhu, H., & Chen, X. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00178h · Cited by 894
Cheng, L., Yang, K., Li, Y., Zeng, X., Shao, M., Lee, S.-T., & Liu, Z. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.11.069 · Cited by 386
Self-citationSun, L.-D., Wang, Y.-F., & Yan, C.-H. (2014) · Accounts of Chemical Research · doi:10.1021/ar400218t · Cited by 363
The biosafety of lanthanide upconversion nanomaterials
Sun, Y., Feng, W., Yang, P., Huang, C., & Li, F. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00175c · Cited by 309
Metadata
- Authors
- Cheng, L., Yang, K., Shao, M., Lee, S.-T., & Liu, Z.
- Venue
- The Journal of Physical Chemistry C
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-01-20
- Volume
- 115
- Issue
- 6
- Pages
- 2686-2692
- ISSN
- 1932-7447 (ISSN-L)
- 1932-7455
- OpenAlex
- W2327559178
- Cited by
- 174
- References
- 0
- FWCI
- 12.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cheng, L., Yang, K., Shao, M., Lee, S.-T., & Liu, Z. (2011). Multicolor In Vivo Imaging of Upconversion Nanoparticles with Emissions Tuned by Luminescence Resonance Energy Transfer. The Journal of Physical Chemistry C. https://doi.org/10.1021/jp111006z
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