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Cited by 384

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Formation of Fluorescent Metal (Au, Ag) Nanoclusters Capped in Bovine Serum Albumin Followed by Fluorescence and Spectroscopy

Le Guével, Xavier, Hötzer, Benjamin, Jung, Gregor, Hollemeyer, Klaus, Trouillet, Vanessa, Schneider, Marc·2011·The Journal of Physical Chemistry C

Abstract

Fluorescent noble metal (Au, Ag) nanoclusters have been biolabeled to bovine serum albumin (BSA) by wet chemistry. Spectroscopic and fluorescence investigations relate the role of the pH and the nature of the reducing agent to the size and the oxidation state of metal clusters. Blue-emitting (λ = 450 nm) small gold nanoclusters (eight atoms) prepared at pH 8 weakly bonded to BSA grow at higher pH to form red-emitting (λ = 690 nm) bigger clusters (25 atoms) covalently bonded to BSA via the sulfur group. X-ray photoelectron spectroscopy (XPS) measurements indicate the presence of Au(I) only for the big clusters. Small silver nanoclusters labeled to the protein with a fluorescence emission in the red region are synthesized in the presence of a strong reducing agent and present only Ag(0). Steady-state and lifetime measurements confirm the crucial impact of the size and the oxidation state of Au(I) on the stabilization of the metal core inside the protein and on the presence of a long lifetime component (τ > 170 ns).

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Crossref · 10.1021/jp111820b

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Metadata

Authors
Le Guével, X., Hötzer, B., Jung, G., Hollemeyer, K., Trouillet, V., & Schneider, M.
Venue
The Journal of Physical Chemistry C
Published
2011-05-13
Volume
115
Issue
22
Pages
10955-10963
ISSN
  • 1932-7447 (ISSN-L)
  • 1932-7455
OpenAlex
W2333610383
Cited by
384
References
27
FWCI
14.25
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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