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Cited by 290

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Biomedical Applications of Shape-Controlled Plasmonic Nanostructures: A Case Study of Hollow Gold Nanospheres for Photothermal Ablation Therapy of Cancer

Zhang, Jin Zhong·2010·The Journal of Physical Chemistry Letters

Abstract

Biomedical applications of plasmonic metal nanostructures represent new and exciting directions of research and development. For instance, photothermal ablation therapy (PTA) based on metal nanomaterials has been actively explored for treating cancer with encouraging success. PTA relies on heat generated from light for destroying cancer cells and thus requires strong optical absorption and high efficiency of photothermal conversion. Desired metal nanostructures for PTA should have strong and tunable SPR, low toxicity, ease of delivery, and convenience for bioconjugation for actively targeting cancer cells. Nanostructures of noble metals, for example, gold and silver, show great promise for PTA applications, including nanoparticles, nanorods, nanoshells, nanocages, and hollow nanospheres. Among these structures, hollow gold nanospheres exhibit a unique combination of small size, spherical shape, and strong, narrow, and tunable SPR. This Perspective highlights the importance of shape control in determining the optical and photothermal properties of metal nanostructures for PTA applications.

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Metadata

Authors
Zhang, J. Z.
Venue
The Journal of Physical Chemistry Letters
Published
2010-01-27
Volume
1
Issue
4
Pages
686-695
ISSN
1948-7185 (ISSN-L)
OpenAlex
W2023144913
Cited by
290
References
1
FWCI
13.88
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Biomedical Applications of Shape-Controlled Plasmonic Nanostructures: A Case Study of Hollow Gold Nanospheres for Photothermal Ablation Therapy of Cancer. https://app.cochat.ai/papers/10.1021/jz900366c
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Zhang, J. Z. (2010). Biomedical Applications of Shape-Controlled Plasmonic Nanostructures: A Case Study of Hollow Gold Nanospheres for Photothermal Ablation Therapy of Cancer. The Journal of Physical Chemistry Letters. https://doi.org/10.1021/jz900366c

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