The DOI matches its Crossref record.
pH-Induced Release from P2VP−PEO Block Copolymer Vesicles
Abstract
The pH-induced release of hydrophilic dyes from poly(2-vinylpyridine-b-ethylene oxide) (P2VP-PEO) block copolymer vesicles is investigated. The structure of the vesicles is characterized using small-angle neutron scattering (SANS) and cryo-electron microscopy (cryo-TEM). A decrease of the pH below 5 leads to protonation and dissolution of the poly-2-vinylpyridine blocks which induces rupture and dissolution of the vesicle membrane. Details of the rupture, dissolution, and release process are studied by fluorescence video microscopy, gel electrophoresis, and high-performance ultrafiltration.
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Citations
Cited by
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Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164
Blanazs, A., Armes, S. P., & Ryan, A. J. (2009) · Macromolecular Rapid Communications · doi:10.1002/marc.200800713 · Cited by 1,500
Stimuli-Responsive Polymersomes for Programmed Drug Delivery
Meng, F., Zhong, Z., & Feijen, J. (2009) · Biomacromolecules · doi:10.1021/bm801127d · Cited by 1,122
Chen, W., Meng, F., Cheng, R., & Zhong, Z. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.09.023 · Cited by 458
pH-Responsive PDMS- b -PDMAEMA Micelles for Intracellular Anticancer Drug Delivery
Car, A., Baumann, P., Duskey, J. T., Chami, M., Bruns, N., & Meier, W. (2014) · Biomacromolecules · doi:10.1021/bm500919z · Cited by 113
Metadata
- Authors
- Borchert, U., Lipprandt, U., Bilang, M., Kimpfler, A., Rank, A., Peschka-Süss, R., Schubert, R., Lindner, P., & Förster, S.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-05-27
- Volume
- 22
- Issue
- 13
- Pages
- 5843-5847
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2046049104
- Cited by
- 163
- References
- 0
- FWCI
- 8.97
- Type
- journal article
- Language
- en
- Open access
- closed
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