The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Fabrication of Supramolecular Hydrogels for Drug Delivery and Stem Cell Encapsulation
Abstract
Supramolecular hydrogels self-assembled by alpha-cyclodextrin and methoxypolyethylene glycol-poly(caprolactone)-(dodecanedioic acid)-poly(caprolactone)-methoxypolyethylene glycol (MPEG-PCL-MPEG) triblock polymers were prepared and characterized in vitro and in vivo. The sustained release of dextran-fluorescein isothiocyanate (FITC) from the hydrogels lasted for more than 1 month, which indicated that the hydrogels were promising for controlled drug delivery. ECV304 cells and marrow mesenchymal stem cells (MSC) were encapsulated and cultured in the hydrogels, during which the morphologies of the cells could be kept. The in vitro cell viability studies and the in vivo histological studies demonstrated that the hydrogels were non-cytotoxic and biocompatible, which indicated that the hydrogels prepared were promising candidates as injectable scaffolds for tissue engineering applications.
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Citations
Cites
Introduction and General Overview of Cyclodextrin Chemistry
Szejtli, J. (1998) · Chemical Reviews · doi:10.1021/cr970022c · Cited by 5,016
Photopolymerizable hydrogels for tissue engineering applications
Nguyen, K. T., & West, J. L. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00175-8 · Cited by 1,669
Cited by
Supramolecular polymeric hydrogels
Appel, E. A., del Barrio, J., Loh, X. J., & Scherman, O. A. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35264h · Cited by 1,159
Cellulose-based hydrogels: Present status and application prospects
Chang, C., & Zhang, L. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.12.023 · Cited by 1,081
In situ-forming injectable hydrogels for regenerative medicine
Yang, J.-A., Yeom, J., Hwang, B. W., Hoffman, A. S., & Hahn, S. K. (2014) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2014.07.006 · Cited by 532
Metadata
- Authors
- Wu, D.-Q., Wang, T., Lu, B., Xu, X.-D., Cheng, S.-X., Jiang, X.-J., Zhang, X.-Z., & Zhuo, R.-X.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-08-05
- Volume
- 24
- Issue
- 18
- Pages
- 10306-10312
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W1970781687
- Cited by
- 158
- References
- 2
- FWCI
- 4.80
- Type
- journal article
- Language
- en
- Open access
- closed
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