The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Coating Electrospun Poly(ε-caprolactone) Fibers with Gelatin and Calcium Phosphate and Their Use as Biomimetic Scaffolds for Bone Tissue Engineering
Abstract
Electrospinning was employed to fabricate fibrous scaffolds of poly(epsilon-caprolactone) in the form of nonwoven mats. The surfaces of the fibers were then coated with gelatin through layer-by-layer self-assembly, followed by functionalization with a uniform coating of bonelike calcium phosphate by mineralization in the 10 times concentrated simulated body fluid for 2 h. Transmission electron microscopy, water contact angle, and scanning electron microscopy measurements confirmed the presence of gelatin and calcium phosphate coating layers, and X-ray diffraction results suggested that the deposited mineral phase was a mixture of dicalcium phosphate dehydrate (a precursor to apatite) and apatite. It was also demonstrated that the incorporation of gelatin promoted nucleation and growth of calcium phosphate. The porous scaffolds could mimic the structure, composition, and biological function of bone extracellular matrix. It was found that the preosteoblastic MC3T3-E1 cells attached, spread, and proliferated well with a flat morphology on the mineralized scaffolds. The proliferation rate of the cells on the mineralized scaffolds was significantly higher (by 1.9-fold) than that on the pristine fibrous scaffolds after culture for 7 days. These results indicated that the hybrid system containing poly(epsilon-caprolactone), gelatin, and calcium phosphate could serve as a new class of biomimetic scaffolds for bone tissue engineering.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Porosity of 3D biomaterial scaffolds and osteogenesis
Karageorgiou, V., & Kaplan, D. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.02.002 · Cited by 6,622
Form and Function in Multilayer Assembly: New Applications at the Nanoscale
Hammond, P. T. (2004) · Advanced Materials · doi:10.1002/adma.200400760 · Cited by 1,251
Biomaterials for bone tissue engineering
Stevens, M. M. (2008) · Materials Today · doi:10.1016/s1369-7021(08)70086-5 · Cited by 1,202
Li, W.-J., Tuli, R., Okafor, C., Derfoul, A., Danielson, K. G., Hall, D. J., & Tuan, R. S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.03.005 · Cited by 929
Badami, A. S., Kreke, M. R., Thompson, M. S., Riffle, J. S., & Goldstein, A. S. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2005.05.084 · Cited by 613
Ma, Z., Kotaki, M., Yong, T., He, W., & Ramakrishna, S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.07.026 · Cited by 558
Gu, H., Yang, Z., Gao, J., Chang, C. K., & Xu, B. (2005) · Journal of the American Chemical Society · doi:10.1021/ja045220h · Cited by 518
Electrospinning: A Simple and Versatile Technique for Producing Ceramic Nanofibers and Nanotubes
Li, D., McCann, J. T., Xia, Y., & Marquez, M. (2006) · Journal of the American Ceramic Society · doi:10.1111/j.1551-2916.2006.00989.x · Cited by 499
Self-citationMa, Z., He, W., Yong, T., & Ramakrishna, S. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.1149 · Cited by 477
Croll, T. I., O'Connor, A. J., Stevens, G. W., & Cooper-White, J. J. (2004) · Biomacromolecules · doi:10.1021/bm0343040 · Cited by 402
Cited by
Advancing biomaterials of human origin for tissue engineering
Chen, F.-M., & Liu, X. (2016) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2015.02.004 · Cited by 1,158
An alternative solvent system for the steady state electrospinning of polycaprolactone
Van der Schueren, L., De Schoenmaker, B., Kalaoglu, Ö. I., & De Clerck, K. (2011) · European Polymer Journal · doi:10.1016/j.eurpolymj.2011.02.025 · Cited by 270
Hajiali, F., Tajbakhsh, S., & Shojaei, A. (2018) · Polymer Reviews · doi:10.1080/15583724.2017.1332640 · Cited by 267
Magnetic‐Field‐Assisted Electrospinning of Aligned Straight and Wavy Polymeric Nanofibers
Liu, Y., Zhang, X., Xia, Y., & Yang, H. (2010) · Advanced Materials · doi:10.1002/adma.200903870 · Cited by 261
Self-citationCho, H.-J., Madhurakkat Perikamana, S. K., Lee, J.-H., Lee, J., Lee, K.-M., Shin, C. S., & Shin, H. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am501391z · Cited by 199
Metadata
- Authors
- Li, X., Xie, J., Yuan, X., & Xia, Y.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-11-16
- Volume
- 24
- Issue
- 24
- Pages
- 14145-14150
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2025289077
- Cited by
- 254
- References
- 38
- FWCI
- 10.45
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Coating Electrospun Poly(ε-caprolactone) Fibers with Gelatin and Calcium Phosphate and Their Use as Biomimetic Scaffolds for Bone Tissue Engineering. https://app.cochat.ai/papers/10.1021/la802984a
- The paper
- Li, X., Xie, J., Yuan, X., & Xia, Y. (2008). Coating Electrospun Poly(ε-caprolactone) Fibers with Gelatin and Calcium Phosphate and Their Use as Biomimetic Scaffolds for Bone Tissue Engineering. Langmuir. https://doi.org/10.1021/la802984a
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
