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Cited by 252

The DOI matches its Crossref record.

Gradient Sensitive Microscopic Probes Prepared by Gold Evaporation and Chemisorption on Latex Spheres

Takei, H., Shimizu, N.·1997·Langmuir
DOI 10.1021/la9621067
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Abstract

We describe a simple yet general method for preparing microscopic probes that are gradient sensitive. Gold was first evaporated on one side of latex spheres, which were then chemically modified by a thiol. As one example, by using thiols with ionizable groups, we prepared microscopic spheres with pH dependent electric dipole moments. Under an electric field such spheres reoriented themselves depending on the pH value of the environment. This method can be naturally extended to other thiol-modified molecules such as dyes and antibodies to prepare various probes that are sensitive to the gradient of the physicochemical microenvironment or that are directional in binding.

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Metadata

Authors
Takei, H., & Shimizu, N.
Venue
Langmuir
Publisher
American Chemical Society (ACS)
Published
1997-04-01
Volume
13
Issue
7
Pages
1865-1868
ISSN
  • 0743-7463 (ISSN-L)
  • 1520-5827
DOI
10.1021/la9621067
OpenAlex
W2008474032
Cited by
252
References
0
FWCI
0.91
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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