Selective dual inhibitors of the cancer-related deubiquitylating proteases USP7 and USP47.

Cited by (198)

Items 101–198 of 198

1. USP7 Inhibits Osteoclastogenesis via Dual Effects of Attenuating TRAF6/TAK1 Axis and Stimulating STING Signaling
   Ziang Xie, Yizheng Wu, Yang Shen, Jiandong Guo, Putao Yuan, Qingliang Ma, Shiyu Wang, Zhiwei Jie, Hongyi Zhou, Shunwu Fan et al. · 2023 · Aging and Disease
2. Covalent Small Molecule Immunomodulators Targeting the Protease Active Site
   Hong‐Rae Kim, Ravichandra Tagirasa, Euna Yoo · 2021 · Journal of Medicinal Chemistry
3. Deubiquitylating enzymes as cancer stem cell therapeutics
   Saba Haq, Bharathi Suresh, Suresh Ramakrishna · 2017 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
4. The role of deubiquitinating enzymes in gastric cancer (Review)
   Jiangang Sun, Xiaojing Shi, MAA Mamun, Yongshun Gao · 2019 · Oncology Letters
5. Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Blood Malignancies
   Blanca T. Gutierrez-Diaz, Wei Jun Gu, Panagiotis Ntziachristos · 2020 · Trends in Immunology
6. DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer
   Francesca Bufalieri, Ludovica Lospinoso Severini, Miriam Caimano, Paola Infante, Lucia Di Marcotullio · 2020 · Cancers
7. Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects
   Mohamad Bakkar, Sara I. Khalil, Komal Bhayekar, Narva Deshwar Kushwaha, Amirreza Samarbakhsh, Sadaf Dorandish, Holly J. Edwards, Q. Ping Dou, Yubin Ge, Navnath S. Gavande · 2025 · Biomolecules
8. USP7 inhibition induces apoptosis in glioblastoma by enhancing ubiquitination of ARF4
   Tingzheng Pan, Xuetao Li, Yanyan Li, Zhennan Tao, Hui Yao, Yue Wu, Guangliang Chen, Kai Zhang, Youxin Zhou, Yulun Huang · 2021 · Cancer Cell International
9. Assay Systems for Profiling Deubiquitinating Activity
   Jinhong Cho, Jin‐Young Park, Eunice EunKyeong Kim, Eun Joo Song · 2020 · International Journal of Molecular Sciences
10. Role of Ubiquitin-Specific Peptidase 47 in Cancers and Other Diseases
    Kailing Pan, Junhao Fu, Wenxia Xu · 2021 · Frontiers in Cell and Developmental Biology
11. Diaryl Sulfoxides from Aryl Benzyl Sulfoxides: A Single Palladium‐Catalyzed Triple Relay Process
    Tiezheng Jia, Ana Bellomo, Sonia Montel, Mengnan Zhang, Kawtar EL Baina, Bing Zheng, Patrick J. Walsh · 2013 · Angewandte Chemie
12. Ubiquitin-Specific Proteases as Druggable Targets.
    Mindy I. Davis, Anton M. Simeonov · 2015 · PubMed
13. USP7 substrates identified by proteomics analysis reveal the specificity of USP7
    Litong Nie, Chao Wang, Xiaoguang Liu, Hongqi Teng, Siting Li, Min Huang, Xu Feng, Guangsheng Pei, Qinglei Hang, Zhongming Zhao et al. · 2022 · Genes & Development
14. An Integrated in silico Approach and in vitro Study for the Discovery of Small‐Molecule USP7 Inhibitors as Potential Cancer Therapies
    Duaa Kanan, Tarek Kanan, Berna Doğan, Müge Didem Orhan, Timuçin Avşar, Serdar Durdağı · 2020 · ChemMedChem
15. Ubiquitin specific peptidases and prostate cancer
    Yunfei Guo, Shuaishuai Cui, Yuanyuan Chen, Song Guo, Dahu Chen · 2023 · PeerJ
16. Structural basis for the bi-specificity of USP25 and USP28 inhibitors
    Jonathan Vincent Patzke, Florian Sauer, Radhika Karal Nair, Erik Endres, Ewgenij Proschak, Víctor Hernández‐Olmos, Christoph Sotriffer, Caroline Kisker · 2024 · EMBO Reports
17. USP7 stabilizes EZH2 and enhances cancer malignant progression.
    Nana Zheng, Man Chu, Min Lin, Youhua He, Zhiwei Peter Wang · 2020 · PubMed Central
18. Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
    Jing Chun Yang, Ellen Weisberg, Shuang Qi, Wei Min NI, Husheng Mei, Zuowei Wang, Chengcheng Meng, Shengzhe Zhang, Mingqi Hou, Ziping Qi et al. · 2022 · Leukemia
19. Targeting HAUSP in both p53 wildtype and p53-mutant tumors
    Omid Tavana, Hongbin Sun, Wei Jun Gu · 2018 · Cell Cycle
20. Targeting the signalling pathways regulated by deubiquitinases for prostate cancer therapeutics
    Md. Tariqul Islam, Xi Zhou, Fangzhi Chen, Md. Asaduzzaman Khan, Junjiang Fu, Hanchun Chen · 2019 · Cell Biochemistry and Function
21. Therapeutic targeting of ubiquitin-specific protease 7 (USP7): Mechanistic insights, dysregulation, and advances in drug discovery
    Anwar A El-Hamaky, Mervat H. El‐Hamamsy, Tarek Fathy El-Moselhy, Nabaweya Sharafeldin, Haytham O. Tawfik · 2025 · European Journal of Medicinal Chemistry
22. Clinical Spectrum of USP8 Pathogenic Variants in Cushing's Disease
    Rosa Rebollar‐Vega, Julia María Zuarth-Vázquez, Laura Cristina Hernández-Ramírez · 2023 · Archives of Medical Research
23. USP47 deubiquitylates Groucho/TLE to promote Wnt–β-catenin signaling
    Sara N. Kassel, Alison J. Hanson, Hassina Benchabane, Kenyi Saito‐Diaz, Carly R. Cabel, Lily Goldsmith, Muhammad Taha, Aksheta Kanuganti, Victoria H. Ng, George Jing Xu et al. · 2023 · Science Signaling
24. The key vulnerabilities and therapeutic opportunities in the USP7-p53/MDM2 axis in cancer
    Gouranga Saha, Mrinal K. Ghosh · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
25. Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer
    Urszula Lucja McClurg, Victoria J. Harle, Arash Nabbi, Amanda Batalha-Pereira, Scott C. Walker, Kelly Coffey, Luke Gaughan, Stuart R. McCracken, Craig N. Robson · 2015 · Oncotarget
26. Discovery of USP7 small-molecule allosteric inhibitors
    Olof Engström, Oscar Belda, Mari Kullman-Magnusson, Mikaela Rapp, Kerstin Böhm, Ralf Paul, Ian M. Henderson, Dean J. Derbyshire, Sofia Karlström, Kevin E. B. Parkes et al. · 2020 · Bioorganic & Medicinal Chemistry Letters
27. A patent review of ubiquitin-specific protease 7 (USP7) inhibitors (2014-present)
    Peng Li, Ying Liu, Hong-Min Liu · 2022 · Expert Opinion on Therapeutic Patents
28. Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma
    Francesca Alessandra Ambrosio, Giosuè Costa, Maria Eugenia Gallo Cantafio, Roberta Torcasio, Francesco Trapasso, Stefano Alcaro, Giuseppe Viglietto, Nicola Amodio · 2023 · Molecules
29. Structural and functional characterization of USP47 reveals a hot spot for inhibitor design
    Sang Chul Shin, Jin‐Young Park, Kyung‐Hee Kim, Jung Min Yoon, Jinhong Cho, Byung Hak Ha, Yeonji Oh, Hyunah Choo, Eun Joo Song, Eunice EunKyeong Kim · 2023 · Communications Biology
30. Inhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells
    Keqiang Zhang, Ting Sun, Wendong Li, Yuming Guo, Aimin Li, Marcus Hsieh, Jinghan Wang, Jun Wu, Leonidas D. Arvanitis, Dan J. Raz · 2023 · Cell Communication and Signaling
31. Deubiquitinating Enzyme: A Potential Secondary Checkpoint of Cancer Immunity
    Xing Huang, Xiaozhen Zhang, Jian Xu, Xun Wang, Gang Zhang, Tianyu Tang, Xiaochao Shen, Tingbo Liang, Xueli Bai · 2020 · Frontiers in Oncology
32. Ubiquitination of Nonhistone Proteins in Cancer Development and Treatment
    Xiuzhen Zhang, Tong Meng, Shuaishuai Cui, Ling Feng, Dongwu Liu, Qiuxiang Pang, Ping Wang · 2021 · Frontiers in Oncology
33. Design, synthesis and biological evaluation of 2-aminopyridine derivatives as USP7 inhibitors
    Xiaoming Xu, Mingchen Wang, Hailong Xu, Na Liu, Kaixian Chen, Cheng Luo, Shijie Chen, Hua Chen · 2022 · Bioorganic Chemistry
34. Parallel synthesis of 2,4,5-trisubstituted thiophene-3-carbonitrile derivatives on traceless solid support
    Suyoun Lee, Doohyun Lee, Kyung‐Sik Song, Kwang‐Hyeon Liu, Young‐Dae Gong, Tae‐Ho Lee · 2014 · Tetrahedron
35. Mechanisms of mitophagy: putting the powerhouse into the doghouse
    Joel S. Riley, Stephen W. G. Tait · 2016 · Biological Chemistry
36. Targeting USP47 enhances the efficacy of KRAS inhibitor in KRASG12C mutated non-small cell lung cancer by controlling deubiquitination of c-Myc
    H. Y. Shin, SuA Hwang, Jeong Hyun Jeong, Sang Chul Shin, Yeonji Oh, Jin Hyeok Kim, Inah Hwang, Eunice EunKyeong Kim, Hyunah Choo, Eun Joo Song · 2025 · Pharmacological Research
37. Targeting FOXP3 complex ensemble in drug discovery
    Jingyao Huang, Shuoyang Wang, Yuxin Jia, Yujia Zhang, Xueyu Dai, Bin Li · 2020 · Advances in protein chemistry and structural biology
38. Steuerung der intrazellulären Proteinmenge durch niedermolekulare Modulatoren des Ubiquitin‐Proteasom‐Systems
    Dennis L. Buckley, Craig M. Crews · 2014 · Angewandte Chemie
39. Discovery of a Potent and Selective Degrader for USP7
    Yuan Pei, Jingfeng Fu, Yunkai Shi, Mengmeng Zhang, Guanghao Luo, Xiaomin Luo, Ning Song, Tian Mi, Yaxi Yang, Jia Xuan Li et al. · 2022 · Angewandte Chemie
40. Discovery of Therapeutic Deubiquitylase Effector Molecules: Current Perspectives
    Benjamin Nicholson, Suresh Kumar, Saket Agarwal, Michael J. Eddins, Jeffrey G. Marblestone, J. Wu, Matthew P. Kodrasov, James P. LaRocque, David E. Sterner, Michael R. Mattern · 2014 · SLAS DISCOVERY
41. Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
    Zhen Zhuang, Yu-Ling Miao, Shanshan Song, Guang-Tong Leng, Xiaofei Zhang, Qian He, Jian Ding, Jin‐Xue He, Chunhao Yang · 2024 · European Journal of Medicinal Chemistry
42. Diarylcarbonates are a new class of deubiquitinating enzyme inhibitor
    Marcus J. C. Long, Ann P. Lawson, Rick Baggio, Qian Yu, Lior Rozhansky, Domenico Fasci, Farid El Oualid, Eranthie Weerapana, Lizbeth Hedstrom · 2018 · Bioorganic & Medicinal Chemistry Letters
43. Comprehensive analysis of the role of ubiquitin-specific peptidases in colorectal cancer: A systematic review
    Eman Al-Balushi, Amina M Al Marzouqi, Shima Tavoosi, Amir Hossein Baghsheikhi, Arash Sadri, Leyla Sharifi Aliabadi, Mohammad-Mahdi Salarabedi, Syed Azizur Rahman, Nabeel Al‐Yateem, Alireza Mosavi Jarrahi et al. · 2024 · World Journal of Gastrointestinal Oncology
44. Harnessing the Oxidation Susceptibility of Deubiquitinases for Inhibition with Small Molecules
    Shimrit Ohayon, Maya Refua, Adi Hendler‐Neumark, Amir Aharoni, Ashraf Brik · 2014 · Angewandte Chemie
45. A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway
    Tekle Pauzaite, James A. Nathan · 2024 · Biochemical Society Transactions
46. Therapeutic potential of targeting ubiquitin-specific proteases in colorectal cancer
    Chern Ein Oon, Padmanabhan Anbazhagan, Chong Teik Tan · 2025 · Drug Discovery Today
47. USP7 at the Crossroads of Ubiquitin Signaling, Cell Cycle, and Tumorigenesis
    Matteo Lusardi, Federica Rapetti, Andrea Spallarossa, Marta Massone, Elena Cichero, Chiara Brullo · 2025 · Molecules
48. USP7 - A novel target for controlling periodontal inflammation through modulation of macrophage polarization
    Yan Wang, Hailin Mu, Chang Yang, Chang Yang, Wei Dong, Jiawei Wang · 2025 · Immunology Letters
49. Ubiquitin specific peptidase 47 promotes proliferation of lung squamous cell carcinoma
    Lin Yu, Jiayu Fu, Chunjian Shen · 2022 · Genes & Genomics
50. Cell-Based Covalent-Capture Deubiquitinase Assay for Inhibitor Discovery
    Megan N. Doleschal, Jenna O. Miller, Sankalp Jain, Alexey V. Zakharov, Ganesha Rai, Anton M. Simeonov, Bolormaa Baljinnyam, Zhihao Zhuang · 2024 · ACS Pharmacology & Translational Science
51. Design, Synthesis, and Molecular Evaluation of S N Ar‐Reactive N ‐(6‐Fluoro‐3‐Nitropyridin‐2‐yl)Isoquinolin‐3‐Amines as Covalent USP7 Inhibitors Reveals an Unconventional Binding Mode
    Larissa N. Ernst, Jason Stahlecker, Finn Mier, Ricardo A. M. Serafim, Valentin R. Wydra, Benedikt Masberg, Simon Jaag, Cornelius Knappe, Michael Lämmerhofer, Thilo Stehle et al. · 2025 · Archiv der Pharmazie
52. Rapid optimization of labeled ubiquitinated peptides for monitoring deubiquitinases activities
    Shimrit Ohayon, Maya Refua, Ashraf Brik · 2015 · Organic & Biomolecular Chemistry
53. Transcription Factors, R-Loops and Deubiquitinating Enzymes: Emerging Targets in Myelodysplastic Syndromes and Acute Myeloid Leukemia
    Silvia M.L. Barabino, Elisabetta Citterio, Antonella Ellena Ronchi · 2021 · Cancers
54. Targeting the Ubiquitin Proteasome System in Cancer
    Nishi Kumari, Kwok Kin Lee, Sudhakar Jha · 2018 · InTech eBooks
55. Identifying Inhibitors of USP7-HDM2 Protein-Protein Interaction (PPI) by the in Silico Fragment-mapping Method
    Kensuke Misawa, Shin-ichiro Ozawa, Tomoki Yoshida, Izumi Nakagome, Noriyuki Yamaotsu, Shuichi Hirono · 2019 · YAKUGAKU ZASSHI
56. Discovery and characterization of potent macrocycle inhibitors of ubiquitin-specific protease-7
    Rafael Miranda, Francesca Anson, Shannon T. Smith, Mark H. Ultsch, Connie A. Tenorio, Lionel Rougé, Brennan Farrell, Emel Adaligil, Jeffrey K. Holden, Seth F. Harris et al. · 2025 · Structure
57. The roles of ubiquitination‐mediated intrinsic apoptotic signalling in cancer therapy
    Tiantian Che, Zhenghong Lin · 2022 · Clinical and Translational Discovery
58. HAUSP Stabilizes SOX2 through Deubiquitination to Maintain Self-renewal and Tumorigenic Potential of Glioma Stem Cells
    Zhi Huang, Kui Zhai, Qiulian Wu, Xiaoguang Fang, Qian Huang, Weiwei Tao, Justin Durla Lathia, Jennifer S. Yu, Jeremy N. Rich, Shideng Bao · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
59. The diverse functions of ubiquitin-specific protease 47 and its role in diseases
    Hu Lei, Hanzhang Xu, Yingli Wu · 2025 · International Journal of Biological Macromolecules
60. Recent Progress of Ubiquitin-Specific-Processing Protease 7 Inhibitors
    L. Chi, Hexiao Wang, F. Yu, C. Gao, H. Dai, Xi. Si, Lifang Liu, Zongyue Wang, Jun-Hui Zheng, Y. Ke et al. · 2023 · Russian Journal of Bioorganic Chemistry
61. Targeting Proteasomal Degradation of Soluble, Misfolded Proteins
    Pierfausto Seneci · 2015 · Elsevier eBooks
62. A small HDM2 antagonist peptide and a USP7 inhibitor synergistically inhibit the p53‐HDM2‐USP7 circuit
    Srijata Mukherjee, Gouranga Saha, Neeladri Sekhar Roy, Gitashri Naiya, Mrinal K. Ghosh, Siddhartha Roy · 2023 · Chemical Biology & Drug Design
63. ob ABPP-HT*: A Precision-Engineered Activity Proteomics Pipeline for the Streamlined Discovery of Deubiquitinase Inhibitors
    Hannah B. L. Jones, Simeon D. Draganov, Sofia Schönbauer Huamán, Peter A. C. Wing, Chuong Nguyen, Zhu Liang, Julia Dörner, Jasper Lithgow, Emma J. Murphy, Alice Beard et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
64. Development and validation of a fluorescence polarization-based assay for USP7: From probe design to inhibitor evaluation
    Siji Chen, Mingchen Wang, Yasi Zeng, Xinyuan Li, Hui Zhong, Yiling Liu, Yunsu Tao, Xu Yang, Cheng Luo, Shijie Chen et al. · 2026 · European Journal of Medicinal Chemistry
65. Unified Total Synthesis of Tryptophan-based Dimeric Diketopiperazine Alkaloids
    Hayato Ishikawa · 2016 · Journal of Synthetic Organic Chemistry Japan
66. Design, synthesis and antitumor activity evaluation of tetrasubstituted pyrimidine derivatives containing methyl phenyl sulfone group
    Chao Gao, Fuqiang Yu, Lingling Chi, Hao Wang, Honglin Dai, Xiaojie Si, Yuze Dong, Hong‐Min Liu, Qiurong Zhang · 2023 · Medicinal Chemistry Research
67. USP7 as part of non-canonical PRC1.1 is a druggable target in leukemia
    Henny Maat, Jennifer Jaques, Aida Rodríguez López, Shanna M. Hogeling, Marcel P. de Vries, Chantal Gravesteijn, Annet Z. Brouwers-Vos, Nisha K. van der Meer, Gerwin A Huls, Edo Vellenga et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
68. USP7 Inhibition Induces Apoptosis in Glioblastoma by Stabilizing ARF4
    Tingzheng Pan, Xuetao Li, Zhennan Tao, Hui Yao, Yue Wu, Guangliang Chen, Kai Zhang, Youxin Zhou, Yu-lun Huang · 2021 · Research Square
69. Structural Insight into the Mechanisms of Activation and Substrate Specificity of Human Deubiquitinating Enzyme USP7
    Alexandra Pozhidaeva · 2016 · OpenCommons at University of Connecticut (University of Connecticut)
70. Peer Review #3 of "Ubiquitin specific peptidases and prostate cancer (v0.1)"
    2023 · PeerJ
71. Peer Review #2 of "Ubiquitin specific peptidases and prostate cancer (v0.1)"
    2023 · PeerJ
72. Peer Review #1 of "Ubiquitin specific peptidases and prostate cancer (v0.1)"
    2023 · PeerJ
73. Peer Review #3 of "Ubiquitin specific peptidases and prostate cancer (v0.2)"
    2023 · PeerJ
74. DEUBIQUITINASES AND THEIR INHIBITORS: CHALLENGES AND RECENT ADVANCES
    Peter R. Hewitt, Oliver Barker, Matthew Helm, Xavier Jacq, Colin R. O'Dowd, Natalie Page, J. S. Shane Rountree, Timothy Harrison · 2022 · Medicinal chemistry reviews
75. Identifying Essential Deubiquitinase Interactions and Targeting Protein Ubiquitination in Cancer
    Johannes Gubat · 2024 · Linköping University medical dissertations
76. An Efficient Synthesis of a Variety of Substituted Pyridine-3-Thiols
    Oleksandr V. Borysov, Dmytro P. Bohdan · 2025 · Journal of organic and pharmaceutical chemistry
77. Structural Plasticity Guides Functional Versatility of USP7 in Human Diseases: Mechanistic Insights and Therapeutic Targeting
    Xuanyu Xu, 张乃霞, Li Shi · 2025 · Health and Metabolism
78. Additional file 3 of USP7 inhibition induces apoptosis in glioblastoma by enhancing ubiquitination of ARF4
    Tingzheng Pan, Li, Xuetao, Li, Yanyan, Zhennan Tao, Yao, Hui, Wu, Yue, Guangliang Chen, Zhang, Kai, YouXin Zhou, Huang, Yulun · 2021 · Figshare
79. Additional file 1 of USP7 inhibition induces apoptosis in glioblastoma by enhancing ubiquitination of ARF4
    Tingzheng Pan, Li, Xuetao, Li, Yanyan, Zhennan Tao, Yao, Hui, Wu, Yue, Guangliang Chen, Zhang, Kai, YouXin Zhou, Huang, Yulun · 2021 · Figshare
80. Additional file 2 of USP7 inhibition induces apoptosis in glioblastoma by enhancing ubiquitination of ARF4
    Tingzheng Pan, Li, Xuetao, Li, Yanyan, Zhennan Tao, Yao, Hui, Wu, Yue, Guangliang Chen, Zhang, Kai, YouXin Zhou, Huang, Yulun · 2021 · Figshare
81. Fonctions et régulations de la kinase CHK1 dans l'hématopoïèse normale et leucémique
    Maëlle Cartel · 2019 · theses.fr (ABES)
82. Activity-Based Proteomics Discovery of Deubiquitinating Enzyme Inhibitors with Immunomodulatory Activity
    Hannah B. L. Jones, Simeon D. Draganov, Sofia Schönbauer Huamán, Peter A. C. Wing, Chuong Nguyen, Zhu Liang, Julia Dörner, Jasper Lithgow, Emma J. Murphy, Alice Beard et al. · 2026 · Research Square
83. Virtual Screening–Guided Identification of Candidate USP7-Inhibitory Scaffolds Exhibiting Antiproliferative Activity
    Rita I. Oliveira, Caio Haddad Franco, Miguel Mano, Ana S. Leal, Jorge A. R. Salvador · 2026 · Pharmaceuticals
84. Synthesis and In Vitro/In Vivo Stability Evaluation of Various Radioiodinated Tyrosine Derivatives
    Weiqi Liu, Minhao Liang, Taiwei Chu · 2026 · Journal of Medicinal Chemistry
85. Activity-based proteomics discovery of deubiquitinating enzyme inhibitors with immunomodulatory activity
    Hannah B. L. Jones, Simeon D. Draganov, Sofia Schönbauer Huamán, Peter A. C. Wing, Chuong Nguyen, Zhu Liang, Julia Dörner, Jasper Lithgow, Emma Murphy, Alice Beard et al. · 2026 · npj Drug Discovery.
86. BindingDB Entry 50002263: Sulawesins A-C, Furanosesterterpene Tetronic Acids That Inhibit USP7, from a Psammocinia sp. Marine Sponge.
    BindingDB · 2020 · UC San Diego
87. BindingDB Entry 50049096: Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors.
    BindingDB · 2019 · UC San Diego
88. BindingDB Entry 50018466: Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors.
    BindingDB · 2024 · UC San Diego
89. BindingDB Entry 50012817: Discovery of USP7 small-molecule allosteric inhibitors.
    BindingDB · 2022 · UC San Diego
90. BindingDB Entry 50007936: Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors.
    BindingDB · 2021 · UC San Diego
91. BindingDB Entry 50013565: Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors.
    BindingDB · 2022 · UC San Diego
92. BindingDB Entry 50017489: Discovery of Orally Bioavailable
    BindingDB · 2023 · UC San Diego
93. BindingDB Entry 50045592: Inhibiting the deubiquitinating enzymes (DUBs).
    BindingDB · 2016 · UC San Diego
94. BindingDB Entry 50043109: Spongiacidin C, a pyrrole alkaloid from the marine sponge Stylissa massa, functions as a USP7 inhibitor.
    BindingDB · 2014 · UC San Diego
95. BindingDB Entry 50022200: Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy.
    BindingDB · 2025 · UC San Diego
96. BindingDB Entry 50021261: Recent advances in the development of deubiquitinases inhibitors as antitumor agents.
    BindingDB · 2025 · UC San Diego
97. BindingDB Entry 50001159: Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies.
    BindingDB · 2020 · UC San Diego
98. BindingDB Entry 50018635: Covalent Small Molecule Immunomodulators Targeting the Protease Active Site.
    BindingDB · 2024 · UC San Diego