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DNA Translocation in Inorganic Nanotubes

Fan, Rong, Karnik, Rohit, Yue, Min, Li, Deyu, Majumdar, Arun, Yang, Peidong·2005·Nano Letters

Abstract

Inorganic nanotubes were successfully integrated with microfluidic systems to create nanofluidic devices for single DNA molecule sensing. Inorganic nanotubes are unique in their high aspect ratio and exhibit translocation characteristics in which the DNA is fully stretched. Transient changes of ionic current indicate DNA translocation events. A transition from current decrease to current enhancement during translocation was observed on changing the buffer concentration, suggesting interplay between electrostatic charge and geometric blockage effects. These inorganic nanotube nanofluidic devices represent a new platform for the study of single biomolecule translocation with the potential for integration into nanofluidic circuits.

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Metadata

Authors
Fan, R., Karnik, R., Yue, M., Li, D., Majumdar, A., & Yang, P.
Venue
Nano Letters
Published
2005-06-28
Volume
5
Issue
9
Pages
1633-1637
ISSN
  • 1530-6984 (ISSN-L)
  • 1530-6992
OpenAlex
W2156862074
Cited by
312
References
0
FWCI
21.20
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: DNA Translocation in Inorganic Nanotubes. https://app.cochat.ai/papers/10.1021/nl0509677
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Fan, R., Karnik, R., Yue, M., Li, D., Majumdar, A., & Yang, P. (2005). DNA Translocation in Inorganic Nanotubes. Nano Letters. https://doi.org/10.1021/nl0509677

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