The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
How to Stabilize Phospholipid Liposomes (Using Nanoparticles)
Abstract
The simple strategy of mixing phospholipid liposomes with charged nanoparticles and using sonication to mix them at low volume fraction produces particle-stabilized liposomes that repel one another and do not fuse. Subsequently, the volume fraction can be raised as high as approximately 50%, reversibly, still without fusion. In studies of liposome longevity, we verified the stability of particle-stabilized liposome suspensions with volume fraction up to 16% for up to 50 days, the longest period investigated. Fluorescent dyes were encapsulated within the particle-stabilized liposomes, without leakage. Although these particle-stabilized liposomes were stable against fusion, approximately 75% of the outer liposome surface remained unoccupied. This opens the door to using particle-stabilized liposomes in various applications.
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Cites
Liposomes in drug delivery: Progress and limitations
Sharma, A. (1997) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(97)00135-x · Cited by 1,253
Cited by
Nanoparticles in Medicine: Therapeutic Applications and Developments
Zhang, L., Gu, F., Chan, J., Wang, A., Langer, R., & Farokhzad, O. (2008) · Clinical Pharmacology & Therapeutics · doi:10.1038/sj.clpt.6100400 · Cited by 2,657
Self-citationMagnetic Nanoparticles: Surface Effects and Properties Related to Biomedicine Applications
Issa, B., Obaidat, I., Albiss, B., & Haik, Y. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141121266 · Cited by 1,245
Al-Jamal, W. T., & Kostarelos, K. (2011) · Accounts of Chemical Research · doi:10.1021/ar200105p · Cited by 696
Nanoparticles: Emerging carriers for drug delivery
Mudshinge, S. R., Deore, A. B., Patil, S., & Bhalgat, C. M. (2011) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2011.04.001 · Cited by 543
Nanoparticle-induced surface reconstruction of phospholipid membranes
Wang, B., Zhang, L., Bae, S. C., & Granick, S. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807296105 · Cited by 469
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Metadata
- Authors
- Zhang, L., & Granick, S.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-02-22
- Volume
- 6
- Issue
- 4
- Pages
- 694-698
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2107102561
- Cited by
- 278
- References
- 1
- FWCI
- 8.46
- Type
- journal article
- Language
- en
- Open access
- closed
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