The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Viral Nanoparticles Donning a Paramagnetic Coat: Conjugation of MRI Contrast Agents to the MS2 Capsid
Abstract
A nanoparticle magnetic resonance imaging (MRI) contrast agent was developed by conjugation of more than 500 gadolinium chelate groups onto a viral capsid. The high density of paramagnetic centers and slow tumbling rate of modified MS2 capsids provided enhanced T1 relaxivities up to 7200 mM-1s-1 per particle. A bimodal imaging agent was generated by sequential conjugation of fluorescein and Gd3+ chelate. These results illustrate the potential for engineering natural protein assemblies to address bionanotechnology applications.
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Citations
Cites
The Refined Structure of Bacteriophage MS2 at 2·8 Å Resolution
Golmohammadi, R., Valegård, K., Fridborg, K., & Liljas, L. (1993) · Journal of Molecular Biology · doi:10.1006/jmbi.1993.1616 · Cited by 303
Cited by
Villaraza, A. J. L., Bumb, A., & Brechbiel, M. W. (2010) · Chemical Reviews · doi:10.1021/cr900232t · Cited by 632
Novel magnetic nanomaterials inspired by magnetotactic bacteria: Topical review
Prozorov, T., Bazylinski, D. A., Mallapragada, S. K., & Prozorov, R. (2013) · Materials Science and Engineering: R: Reports · doi:10.1016/j.mser.2013.04.002 · Cited by 137
Metadata
- Authors
- Anderson, E. A., Isaacman, S., Peabody, D. S., Wang, E. Y., Canary, J. W., & Kirshenbaum, K.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-05-17
- Volume
- 6
- Issue
- 6
- Pages
- 1160-1164
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1966487897
- Cited by
- 196
- References
- 1
- FWCI
- 10.63
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Viral Nanoparticles Donning a Paramagnetic Coat: Conjugation of MRI Contrast Agents to the MS2 Capsid. https://app.cochat.ai/papers/10.1021/nl060378g
- The paper
- Anderson, E. A., Isaacman, S., Peabody, D. S., Wang, E. Y., Canary, J. W., & Kirshenbaum, K. (2006). Viral Nanoparticles Donning a Paramagnetic Coat: Conjugation of MRI Contrast Agents to the MS2 Capsid. Nano Letters. https://doi.org/10.1021/nl060378g
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
