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In Situ Encapsulation of Horseradish Peroxidase in Electrospun Porous Silica Fibers for Potential Biosensor Applications
Abstract
Nanoporous silica nanofibers have been employed as a matrix to encapsulate horseradish peroxide enzymes via a simple electrospinning method. A viscous solution of prehydrolyzed tetramethyl orthosilicate, beta-d-glucose, poly(vinyl alcohol), and enzymes were employed as spinning solution to generate porous fibers in the form of nonwoven mats. The silica fiber mats thus produced have a high surface area because of the small diameter (100 to 200 nm) of the fibers as well as the extreme porosity (2 to 4 nm) of individual fibers caused by the glucose template present in them. The high surface area, mechanical flexibility, thermal stability, reusability, and freedom of encapsulating various enzymes make porous silica nanofibers excellent biosensors.
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Cited by
Electrospun nanofibers in energy and environmental applications
Thavasi, V., Singh, G., & Ramakrishna, S. (2008) · Energy & Environmental Science · doi:10.1039/b809074m · Cited by 934
One‐Dimensional Composite Nanomaterials: Synthesis by Electrospinning and Their Applications
Lu, X., Wang, C., & Wei, Y. (2009) · Small · doi:10.1002/smll.200900445 · Cited by 874
Self-citationBioinspired engineering of honeycomb structure – Using nature to inspire human innovation
Zhang, Q., Yang, X., Li, P., Huang, G., Feng, S., Shen, C., Han, B., Zhang, X., Jin, F., Xu, F., et al. (2015) · Progress in Materials Science · doi:10.1016/j.pmatsci.2015.05.001 · Cited by 836
A Comprehensive Review of Glucose Biosensors Based on Nanostructured Metal-Oxides
Rahman, M. M., Ahammad, A. J. S., Jin, J.-H., Ahn, S. J., & Lee, J.-J. (2010) · Sensors · doi:10.3390/s100504855 · Cited by 762
Nanoparticles meet electrospinning: recent advances and future prospects
Zhang, C.-L., & Yu, S.-H. (2014) · Chemical Society Reviews · doi:10.1039/c3cs60426h · Cited by 665
Metadata
- Authors
- Patel, A. C., Li, S., Yuan, J.-M., & Wei, Y.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-04-20
- Volume
- 6
- Issue
- 5
- Pages
- 1042-1046
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1973215203
- Cited by
- 211
- References
- 0
- FWCI
- 7.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Patel, A. C., Li, S., Yuan, J.-M., & Wei, Y. (2006). In Situ Encapsulation of Horseradish Peroxidase in Electrospun Porous Silica Fibers for Potential Biosensor Applications. Nano Letters. https://doi.org/10.1021/nl0604560
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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