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Carbon Nanotube DNA Sensor and Sensing Mechanism
Abstract
We report the fabrication of single-walled carbon nanotube (SWNT) DNA sensors and the sensing mechanism. The simple and generic protocol for label-free detection of DNA hybridization is demonstrated with random sequence 15mer and 30mer oligonucleotides. DNA hybridization on gold electrodes, instead of on SWNT sidewalls, is mainly responsible for the acute electrical conductance change due to the modulation of energy level alignment between SWNT and gold contact. This work provides concrete experimental evidence on the effect of SWNT-DNA binding on DNA functionality, which will help to pave the way for future designing of SWNT biocomplexes for applications in biotechnology in general and also DNA-assisted nanotube manipulation techniques.
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Cites
Recent advances in biologically sensitive field-effect transistors (BioFETs)
Schöning, M. J., & Poghossian, A. (2002) · The Analyst · doi:10.1039/b204444g · Cited by 566
Cited by
Liu, M., Zeng, G., Wang, K., Wan, Q., Tao, L., Zhang, X., & Wei, Y. (2016) · Nanoscale · doi:10.1039/c5nr09078d · Cited by 561
Potential Applications of Carbon Nanotubes
Endo, M., Strano, M. S., & Ajayan, P. M. (2007) · Topics in Applied Physics · doi:10.1007/978-3-540-72865-8_2 · Cited by 481
Supersensitive, Fast‐Response Nanowire Sensors by Using Schottky Contacts
Hu, Y., Zhou, J., Yeh, P., Li, Z., Wei, T., & Wang, Z. L. (2010) · Advanced Materials · doi:10.1002/adma.201000278 · Cited by 346
Metadata
- Authors
- Tang, X., Bansaruntip, S., Nakayama, N., Yenilmez, E., Chang, Y.-L., & Wang, Q.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-06-29
- Volume
- 6
- Issue
- 8
- Pages
- 1632-1636
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2053699276
- Cited by
- 480
- References
- 1
- FWCI
- 12.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tang, X., Bansaruntip, S., Nakayama, N., Yenilmez, E., Chang, Y.-L., & Wang, Q. (2006). Carbon Nanotube DNA Sensor and Sensing Mechanism. Nano Letters. https://doi.org/10.1021/nl060613v
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
