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Infrared Spectroscopic Mapping of Single Nanoparticles and Viruses at Nanoscale Resolution
Abstract
We demonstrate that scattering near-field microscopy (s-SNOM) can determine infrared "fingerprint" spectra of individual poly(methyl methacrylate) nanobeads and viruses as small as 18 nm. Amplitude and phase spectra are found surprisingly strong, even at a probed volume of only 10(-20) l, and robust in regard to particle size and substrate. This makes infrared spectroscopic s-SNOM a versatile tool for chemical and-in the case of protein-secondary-structure identification.
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Citations
Cited by
Chemical Analysis of Microplastics and Nanoplastics: Challenges, Advanced Methods, and Perspectives
Ivleva, N. P. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00178 · Cited by 1,172
Structural analysis and mapping of individual protein complexes by infrared nanospectroscopy
Amenabar, I., Poly, S., Nuansing, W., Hubrich, E. H., Govyadinov, A. A., Huth, F., Krutokhvostov, R., Zhang, L., Knez, M., Heberle, J., et al. (2013) · Nature Communications · doi:10.1038/ncomms3890 · Cited by 403
Self-citationInfrared study of boron–carbon chemical bonds in boron-doped activated carbon
Romanos, J., Beckner, M., Stalla, D., Tekeei, A., Suppes, G., Jalisatgi, S., Lee, M., Hawthorne, F., Robertson, J. D., Firlej, L., et al. (2013) · Carbon · doi:10.1016/j.carbon.2012.11.031 · Cited by 197
Metadata
- Authors
- Brehm, M., Taubner, T., Hillenbrand, R., & Keilmann, F.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-06-10
- Volume
- 6
- Issue
- 7
- Pages
- 1307-1310
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1968435339
- Cited by
- 250
- References
- 0
- FWCI
- 12.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Brehm, M., Taubner, T., Hillenbrand, R., & Keilmann, F. (2006). Infrared Spectroscopic Mapping of Single Nanoparticles and Viruses at Nanoscale Resolution. Nano Letters. https://doi.org/10.1021/nl0610836
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