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Multiwavelength Photoacoustic Imaging and Plasmon Resonance Coupling of Gold Nanoparticles for Selective Detection of Cancer
Open accessAbstract
Gold nanoparticles targeting epidermal growth factor receptor via antibody conjugation undergo molecular specific aggregation when they bind to receptors on cell surfaces, leading to a red shift in their plasmon resonance frequency. Capitalizing on this effect, we demonstrate the efficacy of the molecular specific photoacoustic imaging technique using subcutaneous tumor-mimicking gelatin implants in ex-vivo mouse tissue. The results of our study suggest that highly selective and sensitive detection of cancer cells is possible using multiwavelength photoacoustic imaging and molecular specific gold nanoparticles.
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Cited by
Nanoparticles as contrast agents for in-vivo bioimaging: current status and future perspectives
Hahn, M. A., Singh, A. K., Sharma, P., Brown, S. C., & Moudgil, B. M. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-4207-5 · Cited by 485
Terahertz plasmonics: The rise of toroidal metadevices towards immunobiosensings
Ahmadivand, A., Gerislioglu, B., Ahuja, R., & Kumar Mishra, Y. (2020) · Materials Today · doi:10.1016/j.mattod.2019.08.002 · Cited by 373
Emerging advances in nanomedicine with engineered gold nanostructures
Webb, J. A., & Bardhan, R. (2014) · Nanoscale · doi:10.1039/c3nr05112a · Cited by 324
Moon, H., Kumar, D., Kim, H., Sim, C., Chang, J.-H., Kim, J.-M., Kim, H., & Lim, D.-K. (2015) · ACS Nano · doi:10.1021/nn506516p · Cited by 266
Magneto‐Plasmonic Au‐Fe Alloy Nanoparticles Designed for Multimodal SERS‐MRI‐CT Imaging
Amendola, V., Scaramuzza, S., Litti, L., Meneghetti, M., Zuccolotto, G., Rosato, A., Nicolato, E., Marzola, P., Fracasso, G., Anselmi, C., et al. (2014) · Small · doi:10.1002/smll.201303372 · Cited by 189
Metadata
- Authors
- Mallidi, S., Larson, T., Tam, J., Joshi, P. P., Karpiouk, A., Sokolov, K., & Emelianov, S.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-07-02
- Volume
- 9
- Issue
- 8
- Pages
- 2825-2831
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2028774780
- Cited by
- 446
- References
- 0
- FWCI
- 19.22
- Type
- journal article
- Language
- en
- Open access
- green
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- Mallidi, S., Larson, T., Tam, J., Joshi, P. P., Karpiouk, A., Sokolov, K., & Emelianov, S. (2009). Multiwavelength Photoacoustic Imaging and Plasmon Resonance Coupling of Gold Nanoparticles for Selective Detection of Cancer. Nano Letters. https://doi.org/10.1021/nl802929u
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