The DOI matches its Crossref record.
On the Antioxidant Mechanism of Curcumin: Classical Methods Are Needed To Determine Antioxidant Mechanism and Activity
Abstract
[reaction: see structure] The antioxidant activity of curcumin (1, 7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) was determined by inhibition of controlled initiation of styrene oxidation. Synthetic nonphenolic curcuminoids exhibited no antioxidant activity; therefore, curcumin is a classical phenolic chain-breaking antioxidant, donating H atoms from the phenolic groups not the CH(2) group as has been suggested (Jovanovic et al. J. Am. Chem. Soc. 1999, 121, 9677). The antioxidant activities of o-methoxyphenols are decreased in hydrogen bond accepting media.
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Cited by
Antioxidant properties of phenols
Foti, M. C. (2007) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.59.12.0010 · Cited by 382
Ishrat, T., Hoda, M. N., Khan, M. B., Yousuf, S., Ahmad, M., Khan, M. M., Ahmad, A., & Islam, F. (2009) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2009.02.002 · Cited by 230
Sienkiewicz, N., Członka, S., Kairyte, A., & Vaitkus, S. (2019) · Polymer Testing · doi:10.1016/j.polymertesting.2019.106046 · Cited by 60
Metadata
- Authors
- Barclay, L. R. C., Vinqvist, M. R., Mukai, K., Goto, H., Hashimoto, Y., Tokunaga, A., & Uno, H.
- Venue
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2000-08-18
- Volume
- 2
- Issue
- 18
- Pages
- 2841-2843
- ISSN
- 1523-7052 (ISSN-L)
- 1523-7060
- OpenAlex
- W1995043836
- Cited by
- 301
- References
- 0
- FWCI
- 2.61
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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