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Cited by 186

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Copper(I) 1,2,3-Triazol-5-ylidene Complexes as Efficient Catalysts for Click Reactions of Azides with Alkynes

Nakamura, Tatsuhito, Terashima, Takahiro, Ogata, Kenichi, Fukuzawa, Shin-ichi·2011·Organic Letters

Abstract

Complexes of copper with 1,4-diphenyl, 1,4-dimesityl, and 1-(2,6-diisopropylphenyl)-4-(3,5-xylyl)-1,2,3-triazol-5-ylidene (abnormal NHC = N-heterocyclic carbene) were prepared by consecutive treatment of the corresponding azolium salts with silver oxide and copper chloride. The new CuCl(aNHC) complexes efficiently catalyzed click reactions of azides with alkynes to give 1,4-substituted 1,2,3-triazoles in excellent yields at room temperature with short reaction times. CuCl(TPh) was particularly effective for the reaction between sterically hindered azides and alkynes.

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Metadata

Authors
Nakamura, T., Terashima, T., Ogata, K., & Fukuzawa, S.-I.
Venue
Organic Letters
Published
2011-01-07
Volume
13
Issue
4
Pages
620-623
ISSN
  • 1523-7052 (ISSN-L)
  • 1523-7060
OpenAlex
W2313056936
Cited by
186
References
2
FWCI
12.87
Type
journal article
Language
en
Open access
closed

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