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Reaction Based Fluorescent Probes for Hydrogen Sulfide
Open accessAbstract
A reaction based fluorescence turn-on strategy for hydrogen sulfide (H(2)S) was developed. This strategy was based on a H(2)S-specific Michael addition-cyclization sequence. Other biological thiols such as cysteine and glutathione did not pursue the reaction and therefore did not turn on the fluorescence/consume the substrates. The probes showed good selectivity and sensitivity for hydrogen sulfide.
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Citations
Cited by
Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
Chan, J., Dodani, S. C., & Chang, C. J. (2012) · Nature Chemistry · doi:10.1038/nchem.1500 · Cited by 1,883
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
Li, X., Gao, X., Shi, W., & Ma, H. (2014) · Chemical Reviews · doi:10.1021/cr300508p · Cited by 1,729
Yu, C., Li, X., Zeng, F., Zheng, F., & Wu, S. (2013) · Chem. Commun. · doi:10.1039/c2cc37329g · Cited by 455
Hydrogen sulfide (H2S) releasing agents: chemistry and biological applications
Zhao, Y., Biggs, T. D., & Xian, M. (2014) · Chem. Commun. · doi:10.1039/c4cc00968a · Cited by 358
Self-citationChemical foundations of hydrogen sulfide biology
Li, Q., & Lancaster, J. R. (2013) · Nitric Oxide · doi:10.1016/j.niox.2013.07.001 · Cited by 334
Metadata
- Authors
- Liu, C., Peng, B., Li, S., Park, C.-M., Whorton, A. R., & Xian, M.
- Venue
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-04-09
- Volume
- 14
- Issue
- 8
- Pages
- 2184-2187
- ISSN
- 1523-7052 (ISSN-L)
- 1523-7060
- OpenAlex
- W2033165499
- Cited by
- 222
- References
- 0
- FWCI
- 14.08
- Type
- journal article
- Language
- en
- Open access
- green
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- Liu, C., Peng, B., Li, S., Park, C.-M., Whorton, A. R., & Xian, M. (2012). Reaction Based Fluorescent Probes for Hydrogen Sulfide. Organic Letters. https://doi.org/10.1021/ol3008183
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