The DOI matches its Crossref record.
Survey of GMP Bulk Reactions Run in a Research Facility between 1985 and 2002
Abstract
A review of reactions scaled in the GMP facilities at the Pfizer-Groton site was undertaken. Reactions were categorized into one of seven categories: carbon−carbon bond formation, carboxylic acid derivative interconversion, carbon−nitrogen bond formation, carbon−oxygen bond formation, red-ox, salt formation/resolution, and other. Reactions scaled from 1997 to 2002 were compared to chemistry scaled from 1985 to 1996 to look for changes in the nature of chemistry being scaled between the two time periods. Reactions were further subcategorized within those categories, and some interesting trends were noted.
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Cited by
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Jad, Y. E., Acosta, G. A., Khattab, S. N., de la Torre, B. G., Govender, T., Kruger, H. G., El-Faham, A., & Albericio, F. (2015) · Organic & Biomolecular Chemistry · doi:10.1039/c4ob02046d · Cited by 92
Metadata
- Authors
- Dugger, R. W., Ragan, J. A., & Ripin, D. H. B.
- Venue
- Organic Process Research & Development
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-04-14
- Volume
- 9
- Issue
- 3
- Pages
- 253-258
- ISSN
- 1083-6160 (ISSN-L)
- 1520-586X
- OpenAlex
- W2032795285
- Cited by
- 309
- References
- 0
- FWCI
- 6.51
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dugger, R. W., Ragan, J. A., & Ripin, D. H. B. (2005). Survey of GMP Bulk Reactions Run in a Research Facility between 1985 and 2002. Organic Process Research & Development. https://doi.org/10.1021/op050021j
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
