The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments
Abstract
Methods for introducing fluorine into organic molecules are reviewed, with an emphasis on preparation of compounds designed for biomedicinal applications. Electrophilic fluorination, nucleophilic fluorination, and enantioselective monofluorination procedures are discussed. This is followed by a review of the development of nucleophilic and electrophilic trifluoromethylation procedures. The final sections highlight recent applications of fluorine chemistry in drug development with selected examples.
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Citations
Cites
Structural mechanism for statin inhibition of HMG-CoA reductase
Istvan, E. S., & Deisenhofer, J. (2001) · Science · doi:10.1126/science.1059344 · Cited by 1,644
Cited by
Copper-Mediated Oxidative Trifluoromethylation of Boronic Acids
Chu, L., & Qing, F.-L. (2010) · Organic Letters · doi:10.1021/ol1023135 · Cited by 382
Tang, X.-J., Thomoson, C. S., & Dolbier, W. R. (2014) · Organic Letters · doi:10.1021/ol502163f · Cited by 323
Metadata
- Authors
- Kirk, K. L.
- Venue
- Organic Process Research & Development
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-01-26
- Volume
- 12
- Issue
- 2
- Pages
- 305-321
- ISSN
- 1083-6160 (ISSN-L)
- 1520-586X
- OpenAlex
- W2170993842
- Cited by
- 1,151
- References
- 1
- FWCI
- 31.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kirk, K. L. (2008). Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments. Organic Process Research & Development. https://doi.org/10.1021/op700134j
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
