Active Metalloproteases of the A Disintegrin And Metalloprotease (ADAM) Family: Biological Function and Structure

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Items 101–180 of 180

1. Proteolytic Landscapes in Gastric Pathology and Cancerogenesis
   Sabine Bernegger, Mirosław Jarząb, Silja Weßler, Gernot Posselt · 2022 · International Journal of Molecular Sciences
2. Multiple non-catalytic ADAMs are novel integrin α4 ligands
   Lei Wang, Jason Andrew Hoggard, Erica Korleski et al. · 2017 · Molecular and Cellular Biochemistry
3. CXCL17-mediated downregulation of type I collagen via MMP1 and miR-29 in skin fibroblasts possibly contributes to the fibrosis in systemic sclerosis
   Shuichi Shimada, Katsunari Makino, Masatoshi Jinnin · 2020 · Journal of Dermatological Science
4. ADAM10 promotes the proliferation of ligamentum flavum cells by activating the PI3K/AKT pathway
   Bin Pan, Tianqun Huo, Menghan Cao · 2020 · International Journal of Molecular Medicine
5. A jack of all trades – ADAM8 as a signaling hub in inflammation and cancer
   Lena Cook, Federico Guillermo Gharzia, Jörg Walter Bartsch, Daniela Yildiz · 2023 · FEBS Journal
6. The influence of zinc levels on osteoarthritis: A comprehensive review
   İbrahim Tekeoğlu, Muhammed Zahid Şahin, Ayhan Kamanlı, Kemal Nas · 2024 · Nutrition Research Reviews
7. Novel Potent Proline-Based Metalloproteinase Inhibitors: Design, (Radio)Synthesis, and First in Vivo Evaluation as Radiotracers for Positron Emission Tomography
   Dmitrii V. Kalinin, Stefan Wagner, Burkhard Riemann, Sven Hermann, Frederike Schmidt, Christoph Becker‐Pauly, Stefan Rose‐John, Michael Andreas Schäfers, Ralph Holl · 2016 · Journal of Medicinal Chemistry
8. Association between V4 polymorphism in the ADAM33 gene and asthma risk: a meta-analysis
   W. Zheng, L. Wang, Xiaojuan Su · 2015 · Genetics and Molecular Research
9. ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells
   Lin Wang, Zhihui Tan, Ying Zhang, Nankoria Kady Keita, Huining Liu, Yu Zhang · 2020 · International Journal of Oncology
10. Decreased collagen type�III synthesis in skin fibroblasts is�associated with parastomal hernia following colostomy
    Fenglin Zhao, Fuqiang Chen, Xin Yuan · 2019 · International Journal of Molecular Medicine
11. ADAM17 Mediates Hypoxia‐Induced Keratinocyte Migration via the p38/MAPK Pathway
    Guoqin Zhu, Jie Liu, Yuan Wang, Naixin Jia, Weiyi Wang, Junhui Zhang, Yi Liang, Hao Tian, Jiaping Zhang · 2021 · BioMed Research International
12. Effects of ADAM2 silencing on isoflurane-induced cognitive dysfunction via the P13K/Akt signaling pathway in immature rats
    Bao-Juan Zhang, Chang-xiu Yuan · 2018 · Biomedicine & Pharmacotherapy
13. Simultaneous detection of multiple proteases using a non-array nanopore platform
    Xiaohan Chen, Youwen Zhang, Xiyun Guan · 2021 · Nanoscale
14. RNAi-mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non-small lung cancer in vitro and in vivo
    Liang Chang, Fangchao Gong, Youbin Cui · 2012 · Molecular Medicine Reports · Retracted
15. Overexpression of ADAM9 in oral squamous cell carcinoma
    Pattaramon Tanasubsinn, Win Pa Pa Aung, Supansa Pata · 2017 · Oncology Letters
16. Human proinsulin production in the milk of transgenic cattle
    Paulo Sérgio Monzani, Juliano Rodrigues Sangalli, Rafael Vilar Sampaio, Samuel Guemra, Renato Zanin, P. R. Adona, Maria Augusta Berlingieri, Luiz F. C. Cunha‐Filho, Irma Yuliana Mora-Ocampo, Carlos Priminho Pirovani et al. · 2024 · Biotechnology Journal
17. The nine ADAMs family members serve as potential biomarkers for immune infiltration in pancreatic adenocarcinoma
    Bing Qi, Han Liu, Ying Dong, Xueying Shi, Qi Zhou, Fen Zeng, Nabuqi Bao, Qian Li, Yuan Yuan, Lei Yao et al. · 2020 · PeerJ
18. Association Between Genetic Polymorphisms in the ADAM33 Gene and Asthma Risk: A Meta-Analysis
    Yu Liu, Zhi-He Wang, Zhen Cheng Wei, LU Si-jing, Liu Xue Zhong, Ling-Yun Zou, Jin-Jiang Xu · 2014 · DNA and Cell Biology
19. The Effect of Tissue Inhibitor of Metalloproteinases on Scar Formation after Spinal Cord Injury
    Raveena R. Mishra, Brooke E. Nielsen, Melissa A. Trudrung, Samuel C. K. Lee, Luke J. Bolstad, Daniel J. Hellenbrand, Amgad S. Hanna · 2024 · Cells
20. Effects of aging on the histology and biochemistry of rat tendon healing
    Fan Lai, Hong Tang, Jingjing Wang et al. · 2021 · BMC Musculoskeletal Disorders
21. ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer
    Ankit Pandey, Hélène Cousin, Brett Horr, Dominique Alfandari · 2023 · Frontiers in Cell and Developmental Biology
22. Handling Metalloproteinases
    Sven Fridrich, Konstantin Karmilin, Walter Stöcker · 2016 · Current Protocols in Protein Science
23. TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective
    Basil Rapoport, Sandra M. McLachlan · 2016 · Endocrine Reviews
24. ADAM9: A novel player in vestibular schwannoma pathogenesis
    Maria Breun, Alexandra Schwerdtfeger, Donato Daniel Martellotta · 2020 · Oncology Letters
25. ADAM Metalloproteinases
    Shuo Wei · 2012 · Handbook of Proteolytic Enzymes
26. Synergistic effects of co-expression plasmid-based ADAM10-specific siRNA and GRIM-19 on hepatocellular carcinoma in vitro and in vivo
    Songyang Liu, Wei Zhang, Kai Liu, YINGCHAO WANG, Bai Ji, Yahui Liu · 2014 · Oncology Reports · Retracted
27. Overexpression of ADAM10 in oral squamous cell carcinoma with metastases
    Olga Stasikowska‐Kanicka, Małgorzata Wągrowska‐Danilewicz, Paulina Kulicka · 2018 · Polish Journal of Pathology
28. Host-Directed Therapy with Inhalable Lovastatin Microspheres for Matrix Metalloproteinase Inhibition in Tuberculosis
    Agrim Jhilta, Krishna Jadhav, Rahul Sharma, Raghuraj Singh, Swarnima Negi, Neelesh Sharma, Amit Kumar Singh, Rahul Kumar Verma · 2025 · ACS Applied Bio Materials
29. Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity
    Théo Klein, Rosa Viner, Christopher M. Overall · 2016 · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
30. Clinical significance of ADAM10 expression in laryngeal carcinoma
    Bo You, Miao Gu, Xiaolei Cao, Xingyu Li, Si Shi, Ying Shan, Yiwen You · 2016 · Oncology Letters
31. Silencing a disintegrin and metalloproteinase‑33 attenuates the proliferation of vascular smooth muscle cells via PI3K/AKT pathway: Implications in the pathogenesis of airway vascular remodeling
    Yan Fang, Yanyan Hao, Xinji Gong · 2021 · Molecular Medicine Reports
32. Expression profile of ADAM10 and ADAM17 in allergic rhinitis
    Hee Won Chueh, Seong Kook Park, Dae Young Hur · 2015 · International Forum of Allergy & Rhinology
33. Hydrogel‐Loaded Exosomes: A Promising Therapeutic Strategy for Musculoskeletal Disorders
    Chunyu Zhang, Xuchang Zhou, Dongxue Wang, Li Hao, Zhipeng Zeng, Lei Su · 2023 · Journal of Clinical Pharmacy and Therapeutics
34. Seminal plasma protects frozen-thawed ram spermatozoa from neutrophil attack: a complement mediated dynamic
    Sophie Warr, Taylor Pini, Simon P. DE GRAAF · 2025 · Reproduction
35. The ADAM33 S2 Polymorphism Is Associated with Susceptibility to Pediatric Asthma in the Chinese Han Population
    Jingang Fan, Zhao-An Wang, Hong‐xiang Zhao · 2015 · Genetic Testing and Molecular Biomarkers
36. Overexpression of A disintegrin and metalloprotease 10 promotes tumor proliferation, migration and poor prognosis in hypopharyngeal squamous cell carcinoma
    Chuanjin Ding, Qicheng Zhang, Yan Chen · 2017 · Oncology Reports
37. Is There a Genetic Correlation between Multiple Sclerosis and Cerebral Aneurysms?
    Fatimah M. Albrekkan, Suha Bachir, Mouhammad A. Jumaa, Syed Fazal Zaidi, Azedine Medhkour · 2016 · World Neurosurgery
38. MMPs in Biology and Medicine
    Di Jia, Roopali Roy, Marsha A. Moses · 2015 · Wiley eBooks
39. Identification and characterization of promoter and regulatory regions for mouse Adam2 gene expression
    Heejin Choi, Boyeon Lee, Sora Jin · 2012 · Molecular Biology Reports
40. A new tool for conditional gene manipulation in a subset of keratin‐expressing epithelia
    Yinqiu Wang, Qiusha Guo, Adam M. Casey · 2012 · genesis
41. Glioma-Associated Proteases
    Petr Bušek, Martin Převorovský, Evzen Krepela, Aleksi Šedo · 2014 · Springer eBooks
42. Notch signaling is essential in collecting duct epithelial cell fate determination during development and maintenance of cell type homeostasis in adult
    Ming‐Zhi Zhang · 2019 · Annals of Translational Medicine
43. Cryopreservation of highly extended pig spermatozoa remodels its proteome and counteracts polyspermic fertilization in vitro
    Inmaculada Parrilla, Josep M. Cambra, Cristina Cuello · 2023 · Andrology
44. A Review of the Pathogenesis of Osteoarthritis and the Use of Intra-articular Platelet Therapy for Joint Disease in Animals and Humans
    Girolamo A. Ortolano, Barry Wenz · 2014 · Bone and Tissue Regeneration Insights
45. Analysis of ADAM9 regulation and function in vestibular schwannoma primary cells
    Anja Nattmann, Maria Breun, Camelia Maria Monoranu · 2020 · BMC Research Notes
46. Hyaluronidase 6 Does Not Affect Cumulus–Oocyte Complex Dispersal and Male Mice Fertility
    Hyewon Bang, Sujin Lee, Pil‐Soo Jeong et al. · 2022 · Genes
47. Insights into the Evolutionary Dynamics: Characterization of Disintegrin and Metalloproteinase Proteins in the Venom Gland Transcriptome of the Hemiscorpius lepturus Scorpion
    Abbas Rami, Benjamin Damizadeh, Mahdi Behdani, Fatemeh Kazemi‐Lomedasht · 2024 · Protein and Peptide Letters
48. ADAM17 and NF-κB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability.
    Lin Gao, Hongbin Liu, Rong Xu · 2021 · PubMed
49. Various effects of ADAM10 and ADAM17 metalloproteases on kidney (dys)function
    Marlena J. Typiak, Agnieszka Piwkowska · 2026 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
50. Functional Analysis of the Pseudoprotease iRhom2 and Nonsense-mediated mRNA Decay Factor Smg1 using Gene Deficient Mice
    David R. McIlwain · 2012 · TSpace (University of Toronto)
51. Investigations into the role of the ErbB4 receptor in cardiomyocyte hypertrophy and adult cardiac function
    Zhen Wang · 2015 · The University of Queensland
52. ADAMs in Cancer
    Dorte Stautz, Sarah Louise Dombernowsky, Marie Kveiborg · 2012
53. A Disintegrin and Metalloproteinase (ADAM) 10 and 17 in Th2 Mediated Responses
    Lauren Folgosa Cooley, Rebecca Martin, Daniel H. Conrad · 2015 · InTech eBooks
54. Transcriptomic and proteomic profiles of vascular cells involved in human abdominal aortic aneurysm
    Florence Pinet, Nicolas Lamblin, Philippe Ratajczak et al. · 2011 · InTech eBooks
55. Expression of Tumor Necrosis Factor-Alpha (TNF-α TNF-α Converting Enzyme and Matrix Metalloproteinase-3 in SAPHO Syndrome Synovium - A Rare Case Accompanied by Acrodermatitis Continua of Hallopeau: A Case Report and Review of Anti-TNF-α Therapy
    Koichiro Komiya, Nobuki Terada, Yoshikazu Mizoguchi · 2012 · InTech eBooks
56. IDENTIFICATION OF MOLECULES RELEVANT FOR THE INVASIVENESS OF FIBROSARCOMAS AND MELANOMAS
    Pirjo Nummela · 2011 · Työväentutkimus Vuosikirja
57. Roles of 5HT1A receptor in CNS neurogenesis and ADAM21 in spinal cord injury.
    Sheila A. Arnold · 2011
58. Cancer – Proteases in the Progression and Metastasis
    Kyungmin Ji, Bonnie F. Sloane · 2015 · Elsevier eBooks
59. The Role of the ADAMTS Proteins in the Intervertebral Disc
    Jason Ho, James D. Wylie, Suneel Apte · 2013 · Springer eBooks
60. Expression of CD13/Aminopeptidase N by Synovial Fibroblasts: Novel Roles in the Pathogenesis of Rheumatoid Arthritis.
    Rachel L. Morgan · 2014 · Deep Blue (University of Michigan)
61. Generation and Characterization of Knockout Mice and Analysis of Patient Material Demonstrates a Role for Tissue Inhibitor of Metalloproteinases 4 (Timp4) in the Cardiovascular System and Tumor Metastasis
    Ilpo Koskivirta · 2012 · UTUPub (University of Turku)
62. Mechanisms of Invasion and Metastasis: Tissue Invasion
    Arthur Zimmermann · 2016 · Springer eBooks
63. Die Rolle der Metalloprotease ADAM17 während der zellulären Seneszenz
    Timo Effenberger · 2014 · Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel)
64. Introduction to the Reprolysins
    Jay W. Fox · 2012 · Handbook of Proteolytic Enzymes
65. Cleavage and nuclear translocation of FGR2B in an endometrial cancer cell line
    Alain A. Mangan · 2016 · Queensland University of Technology
66. Expression of a Disintegrin and Metalloprotease 10 Gene Polymorphisms in a Cohort of Egyptian Patients with Hepatocellular Carcinoma
    Amal Ahmed Mohamed, Dina Mohamed Abo–Elmatty, Omnia Ezzat et al. · 2021 · Current Cancer Therapy Reviews
67. Mechanisms of Invasion and Metastasis: Tissue Invasion
    Arthur Zimmermann · 2016 · Springer eBooks
68. Einfluss von TGF-β auf die EMT-Marker-Expression in Ko-Kulturen oraler Karzinomzellen mit mesenchymalen Stromazellen
    F. Godek · 2021
69. Proteolysis in the Interstitium
    2016 · Protein science series
70. Immunodiagnostics: A Perspective on Sensitivity, Specificity, and Stability of Tumor Antigens
    Stuti Pradhan, Arutselvan Natarajan · 2022 · Springer eBooks
71. ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer
    Ankit Pandey, Hélène Cousin, Brett Horr · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
72. The role of proteolysis in organism
    Z. Kučerová · 2017 · Klinická biochemie a metabolismus
73. Introduction to the reprolysins
    Jay W. Fox · 2025 · Handbook of Proteolytic Enzymes
74. ADAM metalloendopeptidases
    Shuo Wei · 2025 · Handbook of Proteolytic Enzymes
75. Immunodiagnostics: A Perspective on Sensitivity, Specificity, and Stability of Tumor Antigens
    Stuti Pradhan, Arutselvan Natarajan · 2025 · Springer eBooks
76. Additional file 1 of Analysis of ADAM9 regulation and function in vestibular schwannoma primary cells
    Nattmann, Anja, Breun, Maria, Monoranu, Camelia M. · 2020 · Figshare
77. Functional ADAM12 variants modulate proteolytic activity and influence metabolic traits
    Hana Drobiova, A. Al Madhoun, T. Thanaraj, A. Channanath, Prashantha Hebbar, S. Sindhu, Rasheed Ahmad, F. Al-Mulla, R. Al-Temaimi · 2026 · Scientific Reports
78. Targeted shedding of extracellular membrane proteins by induced protease recruitment
    Zi W. Yao, Fangzhu Zhao, Kun Miao, Trenton M. Peters-Clarke, Yun Zhang, Snehal D. Ganjave, Ángel L. Vázquez-Maldonado, Wu Yw, Kaan S. Kumru, Hammam Jumaa et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
79. Future Horizons: Emerging Technologies and Trends in Cancer Research
    Dinesh Kumar, Savita Deokar, Rajib Singh, Shilpa S. Borkar, Debarshi Kar Mahapatra, Puja Gulati, Prashant D. Ghode, Shweta P. Ghode · 2026 · BENTHAM SCIENCE PUBLISHERS eBooks
80. Matrix metalloproteinases (MMPs) in neurodegenerative diseases, an updated overview of the role of MT1-MMP and MT5-MMP in Alzheimer’s disease
    Marielle Frank, Cyrille Barthélémy, Antoine Dufour, Santiago Rivera, Kévin Baranger · 2026 · The Enzymes