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Inhibition of Cytochrome P450 3A4 by a Pyrimidineimidazole: Evidence for Complex Heme Interactions

Hutzler, J. Matthew, Melton, Roger J., Rumsey, Jeanne M., Schnute, Mark E., Locuson, Charles W., Wienkers, Larry C.·2006·Chemical Research in Toxicology
DOI 10.1021/tx060198m
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Metadata

Authors
Hutzler, J. M., Melton, R. J., Rumsey, J. M., Schnute, M. E., Locuson, C. W., & Wienkers, L. C.
Affiliations
Pharmacokinetics, Dynamics and Metabolism (PDM), Department of Medicinal Chemistry, Pfizer Global Research and Development, 700 Chesterfield Parkway West T3A, Chesterfield, Missouri 63017, and Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455
Venue
Chemical Research in Toxicology
Publisher
American Chemical Society (ACS)
Published
2006-11-24
Volume
19
Issue
12
Pages
1650-1659
ISSN
  • 0893-228X
  • 1520-5010
DOI
10.1021/tx060198m
Cited by
38
References
0
Language
en

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CoChat. (2026). Citation check: Inhibition of Cytochrome P450 3A4 by a Pyrimidineimidazole: Evidence for Complex Heme Interactions. https://app.cochat.ai/papers/10.1021/tx060198m
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Hutzler, J. M., Melton, R. J., Rumsey, J. M., Schnute, M. E., Locuson, C. W., & Wienkers, L. C. (2006). Inhibition of Cytochrome P450 3A4 by a Pyrimidineimidazole: Evidence for Complex Heme Interactions. Chemical Research in Toxicology. https://doi.org/10.1021/tx060198m

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