The DOI matches its Crossref record; 16 of the 18 references it cites were found in a registry or an index.
Selective Serotonin Reuptake Inhibitor Usage Patterns as Risk Factors for Hospitalization
Abstract
The authors examined how differences in SSRI utilization affect the risk of hospitalization among persons with depression. In particular, they decompose how different types of drug therapy affect hospitalization and how that effect varies with the usage pattern of the drug. Using retrospective medical and pharmacy claims from a Midwestern health maintenance organization, they employed multiple logistic regression analyses of patients newly treated for depression. Their findings were that (a) paroxetine may be a significant risk factor for early discontinuation compared with fluoxetine; and (b) sertraline initiation among stable-use patients may lower the risk of hospitalization. However, initiation on paroxetine or sertraline rather than fluoxetine may increase the risk of hospitalization among patients not exhibiting a stable usage pattern.
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“Accordingly, the treatment of patients with TRD is associated with an increase in healthcare resource utilization (HCRU) and economic cost, due to a higher number of visits to both primary and secondary care practitioners, a higher rate of hospitalizations, and more psychiatric prescriptions including anxiolytics, hypnotics and antipsychotics 17,19,20 .”
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Antidepressant monotherapy: A claims database analysis of treatment changes and treatment duration
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Young, A. H., Evitt, L., Brignone, M., Diamand, F., Atsou, K., Campbell, R., Cure, S., & Danchenko, N. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.04.019 · Cited by 15
Metadata
- Authors
- Sheffield, R. E., Sasso, A. T. L., Young, C. H., & Way, K.
- Affiliations
- Northwestern University (US)
- Corresponding author
- Sasso, Anthony T. Lo
- ORCID
- Sasso, Anthony T. Lo
- Venue
- Administration and Policy in Mental Health and Mental Health Services Research
- Published
- 2002-11
- Volume
- 30
- Issue
- 2
- Pages
- 121-139
- ISSN
- 0894-587X (ISSN-L)
- 1573-3289
- OpenAlex
- W1586269303
- Cited by
- 11
- References
- 18
- Citations by year
- 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2012: 1
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Administration and Policy in Mental Health and Mental Health Services Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Keywords
- selective serotonin reuptake inhibitors, depression, hospitalization, paroxetine, fluoxetine, sertraline, drug utilization patterns, drug discontinuation, antidepressant initiation, risk factors
- MeSH terms
- Depressive Disorder, Fluoxetine, Health Maintenance Organizations, Hospitalization, Humans, Medical Audit, Retrospective Studies, Risk Factors, Midwestern United States, Selective Serotonin Reuptake Inhibitors, Paroxetine, Drug Utilization Review, Antidepressive Agents, Second-Generation, Sertraline
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- Sheffield, R. E., Sasso, A. T. L., Young, C. H., & Way, K. (2002). Selective Serotonin Reuptake Inhibitor Usage Patterns as Risk Factors for Hospitalization. Administration and Policy in Mental Health and Mental Health Services Research. https://doi.org/10.1023/a%3A1022533118031
