A pilot trial assessing the efficacy of paroxetine hydrochloride (Paxil) in controlling hot flashes in breast cancer survivors.

Stearns, V.; Isaacs, C.; Rowland, J.; Crawford, J.; Ellis, M.J.; Kramer, R.; Lawrence, W.; Hanfelt, J.J.; Hayes, D.F.

doi:10.1023/a:1008382706068

A pilot trial assessing the efficacy of paroxetine hydrochloride (Paxil) in controlling hot flashes in breast cancer survivors.

Background Many breast cancer survivors suffer debilitating hot flashes. Estrogen, the drug of choice in perimenopausal women, is generally not recommenced to breast cancer survivors. Nonhormonal treatments are mostly disappointing. Anecdotal reports in our institution suggested that the selectiv…