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The Neurobiology of Dopamine Signaling
Abstract
The biochemistry of synaptic transmission, especially the neurobiology of dopamine signaling, is discussed.
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“DARPP-32 is activated by D1 receptor cAMP signaling in the NAc by protein kinase A phosphorylation, that regulates the activity of protein phosphatase (PP)-1 [82].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [82]
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Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function
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Self-citationHemmings, H. C., Greengard, P., Tung, H. Y. L., & Cohen, P. (1984) · Nature · doi:10.1038/310503a0 · Cited by 613
Self-citationPhosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
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Self-citationEnhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons
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Self-citationDARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission
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Self-citationSpinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
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Self-citationDopamine-Sensitive Adenyl Cyclase: Possible Role in Synaptic Transmission
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Self-citationRegulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases
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The influence of dopamine receptor SNPs on substance use disorder in a Jordanian cohort
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Metadata
- Authors
- Greengard, P.
- Affiliations
- Rockefeller University (US)
- Corresponding author
- Greengard, Paul
- ORCID
- Greengard, Paul
- Venue
- Bioscience Reports
- Publisher
- Portland Press Ltd.
- Published
- 2001-06-01
- Volume
- 21
- Issue
- 3
- Pages
- 247-269
- ISSN
- 0144-8463 (ISSN-L)
- 1573-4935
- OpenAlex
- W2271932438
- Cited by
- 133
- References
- 21
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 7 · 2019: 7 · 2018: 4 · 2017: 11 · 2016: 8 · 2015: 5 · 2014: 6 · 2013: 4 · 2012: 5
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bioscience Reports (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Northwestern University
- Johns Hopkins University
- University of Texas Southwestern Medical Center
- Karolinska Institutet
- National Institutes of Health
- National Institute of Mental Health
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Keywords
- dopamine signaling, synaptic transmission, neurotransmitter release, dopamine receptors, neuromodulation
- MeSH terms
- Animals, Brain, Dopamine, Humans, Nerve Tissue Proteins, Synaptic Transmission, Phosphoproteins, Receptors, Dopamine, Signal Transduction, Receptors, Glutamate, Presynaptic Terminals, Dopamine and cAMP-Regulated Phosphoprotein 32
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