Acromegalic Arthropathy
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In patients with acromegaly, changes in bone size and density and arthropathy are common problems.
“In patients with acromegaly changes in bone size and density and arthropathy are common problems [31–33].”
From Pituitary Disorders and Osteoporosis (2015) · cites this paper as [31]
The Acromegalic Arthropathy section (page not available in our copy) calls arthropathy one of the most frequent complications of acromegaly and reports joint involvement in many patients. It describes cartilage growth and osteophyte formation, but does not establish that changes in bone size and density are common problems. (LLM, conf=0.88)
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References 13 · Cited by 32
Research works printed but not linked: 13
- Detenbeck LC, Tressler HA, O'Duffy JD, Randall RV. Peripheral joint manifestations of acromegaly. Clin Orthop 1973;91:119- 127.
- Podgorski M, Robinson B, Weissberger A, Stiel J, Wang S, Brooks PM. Articular manifestations of acromegaly. Aust N Z J Med 1988;18:28-35.
- Layton MW, Fudman EJ, Barkan A, Braunstein EM, Fox IH. Acromegalic arthropathy. Characteristics and response to ther- apy. Arthritis Rheum 1988;31:1022-1027.
- Okazaki K, Jingushi S, Ikenoue T, Urabe K, Sakai H, Ohtsuru A, Akino K, Yamashita S, Nomura S, Iwamoto Y. Expression of insulin-like growth factor 1 messenger ribonucleic acid in developing osteophytes in murine experimental osteoarthritis and in rats inoculated with growth hormone-secreting tumor. Endocrinology 1999;140:4821-4830.
- Peterson ME, Taylor RS, Greco DS, Nelson RW, Randolph JF, Foodman MS, Moroff SD, Morrison SA, Lothrop CD. Acromegaly in 14 cats. J Vet Intern Med 1990;4:192-201.
- Bagge E, Eden S, Rosen T, Bengtsson BA. The prevalence of radiographic osteoarthritis is low in elderly patients with growth hormone deficiency. Acta Endocrinol 1993;129:296- 300.
- Dons RF, Rosselet P, Pastakia B, Doppman J, Gorden P. Arthropathy in acromegalic patients before and after treatment: A long-term follow-up study. Clin Endocrinol 1988;28:515-524.
- Chipman JJ, Attanasio AF, Birkett MA, Bates PC, Webb S, Lamberts SW. The safety profile of GH replacement therapy in adults. Clin Endocrinol 1997;46:473-481.
- Johanson NA, Vigorita VJ, Goldman AB, Salvati EA. Acrome- galic arthropathy of the hip. Clin Orthop 1983;173:130-139.
- Lacks S, Jacobs RP. Acromegalic arthropathy: A reversible rheumatic disease. J Rheumatol 1986;13:634-636.
- Roelfsema F, van Dulken H, Frolich M. Long-term results of transsphenoidal pituitary microsurgery in 60 acromegalic pa- tients. Clin Endocrinol 1985;23:555-565.
- Colao A, Marzullo P, Vallone G, Marino V, Annecchino M, Ferone D, De Brasi D, Scarpa R, Oriente P, Lombardi G. Reversibility of joint thickening in acromegalic patients: An ul- trasonography study. J Clin Endocrinol Metab 1998;83:2121- 2125.
- Colao A, Marzullo P, Vallone G, Giaccio A, Ferone D, Rossi E, Scarpa R, Smaltino F, Lombardi G. Ultrasonographic evidence of joint thickening reversibility in acromegalic patients treated with lanreotide for 12 months. Clin Endocrinol 1999;51:611- 618.
- Authors
- Barkan, A. L.
- Affiliations
- Michigan Medicine (US)
- Corresponding author
- Barkan, Ariel L.
- ORCID
- Barkan, Ariel L.
- Venue
- Pituitary
- Published
- 2001-09
- Volume
- 4
- Issue
- 4
- Pages
- 263-264
- ISSN
- 1386-341X (ISSN-L)
- 1573-7403
- OpenAlex
- W4229892564
- Cited by
- 32
- References
- 13
- Citations by year
- 2026: 2 · 2024: 4 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 1 · 2015: 3 · 2014: 2 · 2013: 3
- FWCI
- 0.23
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Pituitary (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
- Health Sciences › Medicine › Rheumatology › Hypertrophic osteoarthropathy and related conditions
- Keywords
- acromegaly, joint diseases, growth hormone excess
- MeSH terms
- Acromegaly, Animals, Hormones, Humans, Insulin-Like Growth Factor I, Joint Diseases, Growth Hormone, Octreotide
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