The Role of Lipid Accumulation in Liver and Muscle for Insulin Resistance and Type 2 Diabetes Mellitus in Humans
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Dysregulation of fatty acid metabolism has a central role in the development of insulin resistance in skeletal muscle.
“Dysregulation of fatty acid metabolism plays a pivotal role in the pathogenesis of insulin resistance in skeletal muscle.”
From Pathogenesis of insulin resistance in skeletal muscle (2010) · cites this paper as [15]
Increased intramyocellular fat content and fatty acid metabolites have a pivotal role in the development of skeletal muscle insulin resistance.
“an increased intramyocellar fat content and fatty acid metabolites have been shown to play a pivotal role in the development of insulin resistance in skeletal muscle [11–15].”
From Pathogenesis of insulin resistance in skeletal muscle (2010) · cites this paper as [15]
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References 74 · Cited by 68
- Authors
- Krssak, M., & Roden, M.
- Affiliations
- Hanusch Hospital (AT)
- Corresponding author
- Roden, Michael
- ORCID
- Roden, Michael
- Venue
- Reviews in Endocrine and Metabolic Disorders
- Published
- 2004-05
- Volume
- 5
- Issue
- 2
- Pages
- 127-134
- ISSN
- 1389-9155 (ISSN-L)
- 1573-2606
- OpenAlex
- W2025841257
- Cited by
- 68
- References
- 74
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 5 · 2019: 3 · 2018: 3 · 2017: 1 · 2016: 5 · 2015: 3 · 2014: 1 · 2013: 5 · 2012: 6
- FWCI
- 2.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Reviews in Endocrine and Metabolic Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Liver Disease Diagnosis and Treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Keywords
- lipid accumulation, insulin resistance, type 2 diabetes, liver, skeletal muscle, hepatic steatosis, muscle lipid metabolism
- MeSH terms
- Animals, Diabetes Mellitus, Type 2, Humans, Insulin Resistance, Lipids, Liver, Muscle, Skeletal, Lipid Metabolism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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