Trauma exposure and Axis I psychopathology: A cotwin control analysis in Norwegian young adults.
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= 2,776), including 449 twin pairs discordant for DSM-IV Criterion A TE. History of TE and Axis I psychopathology was assessed using DSM-IV based clinical interview. Results suggested that TE was significantly associated with greater likelihood of meeting criteria for major depression, dysthymia, anxiety, substance abuse, eating disorders, and somatization disorder in the general population (odds ratios [OR] ranging from 1.33 to 2.21). Among twins discordant for TE, results suggested that TE may exert a direct influence on major depression, dysthymia, anxiety, substance abuse, eating disorders, and somatization disorder. Shared familial effects may also account for at least some of the relationship between TE and major depression. TE may play an important role in the development of a wide range of Axis I psychopathology above and beyond familial factors. Research and clinical implications are discussed.
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Occurrences of violent SLEs increase depression risk when controlling for shared genetic and environmental factors.
“We find that occurrences of violent SLEs increase depression risk when controlling for shared genetic and environmental factors, which aligns with previous studies which have assessed associations between various forms of trauma and depression risk (Brown et al., 2014; McCutcheon et al., 2009).”
From Stressful life events increase the risk of major depressive episodes: A population-based twin study (2023) · cites this paper as Brown et al., 2014
Associations between SLEs and depression may in part reflect non-causal influence or confounding by genetic or familial factors.
“However, it has been found that associations may in part reflect non-causal influence or confounding by genetic or familial factors (Brown et al., 2014; Kendler et al., 1999a; Silberg et al., 2016).”
From Stressful life events increase the risk of major depressive episodes: A population-based twin study (2023) · cites this paper as Brown et al., 2014
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- Authors
- Brown, R. C., Berenz, E. C., Aggen, S. H., Gardner, C. O., Knudsen, G. P., Reichborn-Kjennerud, T., Kendler, K. S., & Amstadter, A. B.
- Affiliations
- Virginia Commonwealth University (US)
- Norwegian Institute of Public Health (NO)
- ORCID
- Venue
- Psychological Trauma: Theory, Research, Practice, and Policy
- Published
- 2014-11
- Volume
- 6
- Issue
- 6
- Pages
- 652-660
- ISSN
- 1942-9681 (ISSN-L)
- 1942-969X
- PMC
- PMC4276315
- OpenAlex
- W2077643189
- Cited by
- 45
- References
- 54
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 8 · 2020: 4 · 2019: 4 · 2018: 5 · 2017: 7 · 2016: 7 · 2014: 1
- FWCI
- 2.97
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychological Trauma Theory Research Practice and Policy (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R37AA011408, P30AA019372, R01AA020179, K99AA022385)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- trauma exposure, major depressive disorder, dysthymia, anxiety disorders, substance abuse, eating disorders, somatization disorder, twin discordance, family influence, young adults
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