The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Chemistry of Visual Adaptation in the Rat
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“In contrast to invertebrates, in which isomerized visual chromophore does not leave the binding pocket and can be re-isomerized back to 11-cis configuration in situ [82,83], vertebrates evolved a relatively complex sequence of enzymatic reactions to facilitate thermodynamically unfavorable isomerization of retinoid independently of light [3,84].”
From Molecular Basis for Vitamin A Uptake and Storage in Vertebrates (2016) · cites this paper as [84]
Citations
Cites
CIS-TRANS ISOMERS OF VITAMIN A AND RETINENE IN THE RHODOPSIN SYSTEM
Hubbard, R., & Wald, G. (1952) · Journal of General Physiology · doi:10.1085/jgp.36.2.269 · Cited by 422
Wald, G., Brown, P. K., & Smith, P. H. (1955) · The Journal of General Physiology · doi:10.1085/jgp.38.5.623 · Cited by 324
CAROTENOIDS AND THE VISUAL CYCLE
Wald, G. (1935) · The Journal of General Physiology · doi:10.1085/jgp.19.2.351 · Cited by 302
VITAMIN A DEFICIENCY AND NIGHT BLINDNESS
Dowling, J. E., & Wald, G. (1958) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.44.7.648 · Cited by 276
Self-citationThe regeneration of visual purple: its relation to dark adaptation and night blindness
Tansley, K. (1931) · The Journal of Physiology · doi:10.1113/jphysiol.1931.sp002749 · Cited by 175
Measurement of the scotopic pigment in the living human eye
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Hubbard, R. (1956) · The Journal of General Physiology · doi:10.1085/jgp.39.6.935 · Cited by 145
THE NEO-b ISOMER OF VITAMIN A AND RETINENE
Brown, P., & Wald, G. (1956) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)89944-x · Cited by 142
THE ENZYMATIC ESTERIFICATION OF VITAMIN A
Krinsky, N. I. (1958) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77407-9 · Cited by 123
On the Mechanism of the Visual Threshold and Visual Adaptation
Wald, G. (1954) · Science · doi:10.1126/science.119.3104.887 · Cited by 114
AN EXPERIMENT IN HUMAN DIETARY NIGHT-BLINDNESS
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Glover, J., Goodwin, T. W., & Morton, R. A. (1947) · Biochemical Journal · doi:10.1042/bj0410097 · Cited by 92
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Physical Measurement of Cone Pigment in the Living Human Eye
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Research works printed but not linked: 3
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Cited by
Sorted by citations
Allikmets, R., Singh, N., Sun, H., Shroyer, N. F., Hutchinson, A., Chidambaram, A., Gerrard, B., Baird, L., Stauffer, D., Peiffer, A., et al. (1997) · Nature Genetics · doi:10.1038/ng0397-236 · Cited by 1,435
Retinal damage by light in rats.
Noell, W. K., Walker, V. S., Kang, B. S., & Berman, S. (1966) · PubMed · Cited by 1,107
Dark adaptation and the retinoid cycle of vision
Lamb, T. D., & Pugh, E. N. (2004) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2004.03.001 · Cited by 725
The retinal pigment epithelium: a versatile partner in vision
Bok, D. (1993) · Journal of Cell Science · doi:10.1242/jcs.1993.supplement_17.27 · Cited by 593
Changes in time scale and sensitivity in turtle photoreceptors
Baylor, D. A., & Hodgkin, A. L. (1974) · The Journal of Physiology · doi:10.1113/jphysiol.1974.sp010732 · Cited by 530
Metadata
- Authors
- DOWLING, J. E.
- Affiliations
- Harvard University (US)
- Corresponding author
- DOWLING, JOHN E.
- ORCID
- DOWLING, JOHN E.
- Venue
- Nature
- Published
- 1960-10
- Volume
- 188
- Issue
- 4745
- Pages
- 114-118
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1992632065
- Cited by
- 543
- References
- 21
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 3 · 2018: 5 · 2017: 4 · 2016: 5 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 5
- FWCI
- 5.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Development and Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Photoreceptor and optogenetics research
- Keywords
- visual adaptation, rhodopsin, retinal pigment epithelium, phototransduction, rod photoreceptors, rat retina, light adaptation
- MeSH terms
- Acclimatization, Adaptation, Ocular, Adaptation, Physiological, Animals, Eye, Head, Rats
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