A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

New Technique for Distinguishing between Human Chromosomes

Sumner, A. T., Evans, H. J., & Buckland, R. A. (1971) · Nature New Biology · doi:10.1038/newbio232031a0 · Cited by 1,166

Technique for Identifying Y Chromosomes in Human Interphase Nuclei

Pearson, P. L., Bobrow, M., & Vosa, C. G. (1970) · Nature · doi:10.1038/226078a0 · Cited by 455

DNA Contents of Chromosome Ph 1 and Chromosome 21 in Human Chronic Granulocytic Leukemia

Rudkin, G. T., Hungerford, D. A., & Nowell̀, P. C. (1964) · Science · doi:10.1126/science.144.3623.1229 · Cited by 199

Clinical Implications of Cytogenetic Variants in Chronic Myelocytic Leukemia (CML)

Whang‐Peng, J., Canellos, G. P., Carbone, P. P., & TJIO, J. H. (1968) · Blood · doi:10.1182/blood.v32.5.755.755 · Cited by 179

Philadelphia-Chromosome-Positive and -Negative Chronic Myelocytic Leukemia

Ezdinli, E. Z., SOKAL, J. E., CROSSWHITE, L., & SANDBERG, A. A. (1970) · Annals of Internal Medicine · doi:10.7326/0003-4819-72-2-175 · Cited by 177

Identification of the Philadelphia chromosome as a number 22 by quinacrine mustard fluorescence analysis

Caspersson, T. O., Gahrton, G., Lindsten, J., & Zech, L. (1970) · Experimental Cell Research · doi:10.1016/0014-4827(70)90362-9 · Cited by 172

Chromosome Studies in Preleukemia

Rowley, J. D., Blaisdell, R. K., Jacobson, L., Mikuta, J. C., Byrne, R., & Shepley, L. A. (1966) · Blood · doi:10.1182/blood.v27.6.782.782 · Cited by 132

Distinguishing between the Chromosomes involved in Down's Syndrome (Trisomy 21) and Chronic Myeloid Leukaemia (Ph1) by Fluorescence

O'Riordan, M. L., Robinson, J. A., BUCKTON, K. E., & Evans, H. J. (1971) · Nature · doi:10.1038/230167a0 · Cited by 129

Identification by fluorescence of the G chromosome lost in human meningomas

Mark, J., Levan, G., & Mitelman, F. (2009) · Hereditas · doi:10.1111/j.1601-5223.1972.tb01017.x · Cited by 115

IDENTIFICATION OF ISOCHROMOSOME 17 IN MYELOID LEUKÆMIA

Lobb, D., Reeves, B. R., & Lawler, S. (1972) · The Lancet · doi:10.1016/s0140-6736(72)90836-7 · Cited by 48

DPPIV (CD26) as a novel stem cell marker in Ph+ chronic myeloid leukaemia

Valent, P., Sadovnik, I., Ráčil, Z., Herrmann, H., Blatt, K., Cerny‐Reiterer, S., Eisenwort, G., Lion, T., Holyoake, T. L., & Mayer, J. (2014) · European Journal of Clinical Investigation · doi:10.1111/eci.12368 · Cited by 64

The Role of Nrf2 and Cytoprotection in Regulating Chemotherapy Resistance of Human Leukemia Cells

Rushworth, S. A., & MacEwan, D. J. (2011) · Cancers · doi:10.3390/cancers3021605 · Cited by 63

Eradication of Chronic Myeloid Leukemia Stem Cells: A Novel Mathematical Model Predicts No Therapeutic Benefit of Adding G-CSF to Imatinib

Foo, J., Drummond, M. W., Clarkson, B. D., Holyoake, T. L., & Michor, F. (2009) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000503 · Cited by 65

Chronic Myeloid Leukemia: Current Application of Cytogenetics and Molecular Testing for Diagnosis and Treatment

Tefferi, A., Dewald, G. W., Litzow, M. L., Cortes, J. E., Mauro, M. J., Talpaz, M., & Kantarjian, H. M. (2005) · Mayo Clinic Proceedings · doi:10.4065/80.3.390 · Cited by 63

The Anatomy of the Human Genome

McKusick, V. A. (2001) · JAMA · doi:10.1001/jama.286.18.2289 · Cited by 63

Cytogenetic, biochemical, and molecular analyses of a 22q13 deletion

Phelan, M. C., Thomas, G. R., Saul, R. A., Rogers, R. C., Taylor, H. A., Wenger, D. A., & McDermid, H. E. (1992) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320430524 · Cited by 63

Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA

Kuwabara, T. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.15.3074 · Cited by 63

Antibody recognition of the tumor-specific bcr-abl joining region in chronic myeloid leukemia.

Denderen, J. V., Hermans, A., Boer, T. M.-D., Troelstra, C., Zegers, N. D., Boersma, W. J. A., Grosveld, G. C., & van Ewijk, W. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.169.1.87 · Cited by 63

The Rho-specific Guanine Nucleotide Exchange Factor Dbs Regulates Breast Cancer Cell Migration

Liu, Z., Adams, H., & Whitehead, I. P. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m901853200 · Cited by 62

Chimeric RNAs and their implications in cancer

Li, Z., Qin, F., & Li, H. (2017) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2017.10.002 · Cited by 63

Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia

Massimino, M., Stella, S., Tirrò, E., Romano, C., Pennisi, M. S., Puma, A., Manzella, L., Zanghì, A., Stagno, F., Raimondo, F. D., et al. (2018) · Molecular Cancer · doi:10.1186/s12943-018-0805-1 · Cited by 64

Sources of Cancer Neoantigens beyond Single-Nucleotide Variants

Capietto, A.-H., Hoshyar, R., & Delamarre, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710131 · Cited by 63

From the Biology of PP2A to the PADs for Therapy of Hematologic Malignancies

Ciccone, M., Călin, G. A., & Perrotti, D. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00021 · Cited by 62

Molecular and cellular bases of chronic myeloid leukemia

Chen, Y., Peng, C., Li, D., & Li, S. (2010) · Protein & Cell · doi:10.1007/s13238-010-0016-z · Cited by 63

Inducible expression of BCR/ABL using human CD34 regulatory elements results in a megakaryocytic myeloproliferative syndrome

Huettner, C. S., Koschmieder, S., Iwasaki, H., Iwasaki-Arai, J., Radomska, H. S., Akashi, K., & Tenen, D. G. (2003) · Blood · doi:10.1182/blood-2003-03-0768 · Cited by 65

Selective elimination of leukemia stem cells: Hitting a moving target

Crews, L. A., & Jamieson, C. H. M. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.08.006 · Cited by 63

Inter-Laboratory Comparison of Chronic Myeloid Leukemia Minimal Residual Disease Monitoring

Zhang, T., Grenier, S., Nwachukwu, B., Wei, C., Lipton, J. H., & Kamel‐Reid, S. (2007) · Journal of Molecular Diagnostics · doi:10.2353/jmoldx.2007.060134 · Cited by 62

Best Practices in Chronic Myeloid Leukemia Monitoring and Management

Soverini, S., Benedittis, C. D., Mancini, M., & Martinelli, G. (2016) · The Oncologist · doi:10.1634/theoncologist.2015-0337 · Cited by 62

Ph-positive chronic myeloid leukemia with near-haploid conversion in vivo and establishment of a continuously growing cell line with similar cytogenetic pattern

Andersson, B. S., Beran, M., Pathak, S., Goodacre, A., Barlogie, B., & McCredie, K. B. (1987) · Cancer Genetics and Cytogenetics · doi:10.1016/0165-4608(87)90116-6 · Cited by 62

Chronic myeloid leukemia may be associated with several bcr-abl transcripts including the acute lymphoid leukemia-type 7 kb transcript [see comments]

Selleri, L., Lindern, M. V., Hermans, A., Meijer, D., Torelli, G., & Grosveld, G. C. (1990) · Blood · doi:10.1182/blood.v75.5.1146.1146 · Cited by 62

NUP98 gene rearrangements and the clonal evolution of chronic myelogenous leukemia

Ahuja, H. G., Popplewell, L. L., Tcheurekdjian, L., & Slovak, M. L. (2001) · Genes Chromosomes and Cancer · doi:10.1002/1098-2264(2001)9999:9999 · Cited by 62

Identification of molecular variants of p210bcr-abl in chronic myelogenous leukemia

Kurzrock, R., Kloetzer, W. S., Talpaz, M., Blick, M. B., Walters, R. S., Arlinghaus, R. B., & Gutterman, J. U. (1987) · Blood · doi:10.1182/blood.v70.1.233.bloodjournal701233 · Cited by 62

Fundamental science behind today’s important medicines

Spector, J., Harrison, R. S., & Fishman, M. C. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aaq1787 · Cited by 63

Cytokine Regulation of Microenvironmental Cells in Myeloproliferative Neoplasms

Hoermann, G., Greiner, G., & Valent, P. (2015) · Mediators of Inflammation · doi:10.1155/2015/869242 · Cited by 61

Cancer Cytogenetics: Methodology Revisited

Wan, T. S. K. (2014) · Annals of Laboratory Medicine · doi:10.3343/alm.2014.34.6.413 · Cited by 61

The interferon-alpha revival in CML

Talpaz, M., Mercer, J., & Hehlmann, R. (2015) · Annals of Hematology · doi:10.1007/s00277-015-2326-y · Cited by 64

Emerging stem cell concepts for imatinib‐resistant chronic myeloid leukaemia: implications for the biology, management, and therapy of the disease

Valent, P. (2008) · British Journal of Haematology · doi:10.1111/j.1365-2141.2008.07197.x · Cited by 63

Diagnostic gold standard for soft tissue tumours: morphology or molecular genetics?

Pfeifer, J. D., Hill, D. A., O’Sullivan, M. J., & Dehner, L. P. (2000) · Histopathology · doi:10.1046/j.1365-2559.2000.01107.x · Cited by 61

Biology of the Human Malignant Lymphomas

Epstein, A. L., & Kaplan, H. S. (1978) · Recent results in cancer research/Recent Results in Cancer Research · doi:10.1007/978-3-642-81246-0_21 · Cited by 61

Chronic myelogenous leukaemia with p185BCR/ABL expression: characteristics and clinical significance

Ravandi, F., Cortes, J. E., Albitar, M. X., Arlinghaus, R. B., Guo, J. Q., Talpaz, M., & Kantarjian, H. M. (1999) · British Journal of Haematology · doi:10.1046/j.1365-2141.1999.01736.x · Cited by 61

The Molecular Genetics of Recurring Chromosome Abnormalities in Acute Myeloid Leukemia

Hayashi, Y. (2000) · Seminars in Hematology · doi:10.1016/s0037-1963(00)90017-9 · Cited by 61

Acute leukemias?prognostic factors and treatment strategies

B�chner, T. (1989) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/bf00400972 · Cited by 61

Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation

Liu, H., Ding, X., Liu, L., Mi, Q., Zhao, Q., Shao, Y., Ren, C., Chen, J., Kong, Y., Qiu, X., et al. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.113645 · Cited by 60

The legacy of the Philadelphia chromosome

Koretzky, G. A. (2007) · Journal of Clinical Investigation · doi:10.1172/jci33032 · Cited by 60

Role of BCR/ABL gene-expression levels in determining the phenotype and imatinib sensitivity of transformed human hematopoietic cells

Modi, H., McDonald, T., Chu, S., Yee, J., Forman, S. J., & Bhatia, R. (2007) · Blood · doi:10.1182/blood-2006-06-032490 · Cited by 60

Identification of mTOR as a novel bifunctional target in chronic myeloid leukemia: dissection of growth‐inhibitory and VEGF‐suppressive effects of rapamycin in leukemic cells

Mayerhofer, M., Aichberger, K. J., Florian, S., Krauth, M., Hauswirth, A. W., Derdak, S. V., Sperr, W. R., Esterbauer, H., Wagner, O. F., Marosi, C., et al. (2005) · The FASEB Journal · doi:10.1096/fj.04-1973fje · Cited by 60

Phosphotyrosine Antibodies Identify the p210 c- abl Tyrosine Kinase and Proteins Phosphorylated on Tyrosine in Human Chronic Myelogenous Leukemia Cells

Naldini, L., Stacchini, A., Cirillo, D. M., Aglietta, M., Gavosto, F., & Comoglio, P. M. (1986) · Molecular and Cellular Biology · doi:10.1128/mcb.6.5.1803 · Cited by 60

Chronic myeloid leukemia from basics to bedside

Thijsen, S. F. T., Schuurhuis, G. J., Oostveen, J. W. V., & Ossenkoppele, G. J. (1999) · Leukemia · doi:10.1038/sj.leu.2401565 · Cited by 60

Multiple karyotypic changes in retinoblastoma tumor cells: Presence of normal chromosome No. 13 in most tumors

Gardner, H. A., Gallie, B. L., Knight, L. A., & Phillips, R. A. (1982) · Cancer Genetics and Cytogenetics · doi:10.1016/0165-4608(82)90057-7 · Cited by 60

Clonal and Stem Cell Origin of Blood Cell Neoplasms

Fialkow, P. J. (1980) · Springer eBooks · doi:10.1007/978-1-4684-3575-7_1 · Cited by 60

THE MOLECULAR BIOLOGY OF CHRONIC MYELOGENOUS LEUKAEMIA

Gale, R. P., & Cannani, E. (1985) · British Journal of Haematology · doi:10.1111/j.1365-2141.1985.tb07436.x · Cited by 60

Scrambling the genome in cancer: causes and consequences of complex chromosome rearrangements

Krupina, K., Goginashvili, A., & Cleveland, D. W. (2023) · Nature Reviews Genetics · doi:10.1038/s41576-023-00663-0 · Cited by 63

Acute dasatinib exposure commits Bcr-Abl–dependent cells to apoptosis

Snead, J. L., O’Hare, T., Adrian, L. T., Eide, C. A., Lange, T., Druker, B. J., & Deininger, M. W. (2009) · Blood · doi:10.1182/blood-2007-10-113969 · Cited by 59

Role of stromal microenvironment in nonpharmacological resistance of CML to imatinib through Lyn/CXCR4 interactions in lipid rafts

Tabe, Y., Jin, L., Iwabuchi, K., Wang, R.-Y., Ichikawa, N., Miida, T., Cortes, J. E., Andreeff, M., & Konopleva, M. Y. (2011) · Leukemia · doi:10.1038/leu.2011.291 · Cited by 59

Genetics of Myeloproliferative Neoplasms

Viny, A. D., & Levine, R. L. (2014) · The Cancer Journal · doi:10.1097/ppo.0000000000000013 · Cited by 60

Cytogenetics of the Chronic Myeloid Leukemia-Derived Cell Line K562

Gribble, S. M., Roberts, I., Grace, C. D., Andrews, K. M., Green, A. R., & Nacheva, E. P. (2000) · Cancer Genetics and Cytogenetics · doi:10.1016/s0165-4608(99)00169-7 · Cited by 59

Characterizing and optimizing immune responses to leukaemia antigens after allogeneic stem cell transplantation

Rezvani, K., & Barrett, A. J. (2008) · Best Practice & Research Clinical Haematology · doi:10.1016/j.beha.2008.07.004 · Cited by 59

Computational Analysis of the Binding Specificity of Gleevec to Abl, c-Kit, Lck, and c-Src Tyrosine Kinases

Lin, Y.-L., & Roux, B. (2013) · Journal of the American Chemical Society · doi:10.1021/ja405939x · Cited by 62

Variant Ph translocations in chronic myeloid leukemia

Heim, S., Billström, R., Kristoffersson, U., Mandahl, N., Strömbeck, B., & Mitelman, F. (1985) · Cancer Genetics and Cytogenetics · doi:10.1016/0165-4608(85)90086-x · Cited by 59

The chromosome number in humans: a brief history

Gartler, S. M. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1917 · Cited by 59

Clinical and biological importance of cytogenetic abnormalities in childhood and adult acute lymphoblastic leukemia

Johansson, B., Mertens, F., & Mitelman, F. (2004) · Annals of Medicine · doi:10.1080/07853890410018808 · Cited by 59

Identification of BCR/ABL-negative primitive hematopoietic progenitor cells within chronic myeloid leukemia marrow

Leemhuis, T., Leibowitz, D. S., Cox, G., Silver, R., Srour, E. F., Tricot, G. J. K., & Hoffman, R. (1993) · Blood · doi:10.1182/blood.v81.3.801.801 · Cited by 59

Reconstruction of hundreds of reference ancestral genomes across the eukaryotic kingdom

Muffato, M., Louis, A., Nguyen, N. T. T., Lucas, J. M., Berthelot, C., & Crollius, H. R. (2023) · Nature Ecology & Evolution · doi:10.1038/s41559-022-01956-z · Cited by 60

A framework for the clinical implementation of optical genome mapping in hematologic malignancies

Levy, B., Kanagal‐Shamanna, R., Sahajpal, N., Neveling, K., Rack, K. A., Dewaele, B., Weghuis, D. O., Stevens‐Kroef, M., Puiggros, A., Mallo, M., et al. (2024) · American Journal of Hematology · doi:10.1002/ajh.27175 · Cited by 58

Science and Technology for Disease Control: Past, Present, and Future

Weatherall, D. J., Greenwood, B. M., Chee, H. L., & Wasi, P. (2006) · Europe PMC (PubMed Central) · Cited by 58

Inhibition of Polysome Assembly Enhances Imatinib Activity against Chronic Myelogenous Leukemia and Overcomes Imatinib Resistance

Zhang, M., Fu, W., Prabhu, S., Moore, J. C., Ko, J., Kim, J. W., Druker, B. J., Trapp, V., Fruehauf, J. P., Gram, H., et al. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00477-08 · Cited by 59

Aneuploidy in pluripotent stem cells and implications for cancerous transformation

Na, J., Baker, D., Zhang, J., Andrews, P. W., & Barbaric, I. (2014) · Protein & Cell · doi:10.1007/s13238-014-0073-9 · Cited by 60

Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases

Greer, S., Nadauld, L. D., Lau, B. T., Chen, J., Wood-Bouwens, C. M., Ford, J. M., Kuo, C. J., & Ji, H. P. (2017) · Genome Medicine · doi:10.1186/s13073-017-0447-8 · Cited by 58

Imatinib Resistance: Obstacles and Opportunities

Litzow, M. R. (2006) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2006-130-669-iroao · Cited by 59

The promise of molecular targeted therapies: Protein kinase inhibitors in the treatment of cutaneous malignancies

Kondapalli, L., Soltani, K., & Lacouture, M. E. (2005) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2005.02.011 · Cited by 58

Long-range mapping of the Philadelphia chromosome by pulsed-field gel electrophoresis

Westbrook, C. A., Rubin, C., Carrino, J. J., Beau, M. M. L., Bernards, A., & Rowley, J. (1988) · Blood · doi:10.1182/blood.v71.3.697.697 · Cited by 58

STI571 as a Targeted Therapy for CML

O'Dwyer, M. E., Mauro, M. J., & Druker, B. J. (2003) · Cancer Investigation · doi:10.1081/cnv-120018235 · Cited by 58

Human lymphocyte telomerase is genetically regulated

Kosciolek, B. A., & Rowley, P. T. (1998) · Genes Chromosomes and Cancer · doi:10.1002/(sici)1098-2264(199802)21:2 · Cited by 42

Chromosomal Abnormalities in Leukemia and Lymphoma: Clinical and Biological Significance

Beau, M. M. L., & Rowley, J. D. (1986) · Springer eBooks · doi:10.1007/978-1-4615-8356-1_1 · Cited by 58

Discordant maturation as the primary biological defect in chronic myelogenous leukemia.

Strife, A., Lambek, C. L., Wisniewski, D. J., Wachter, M., Gulati, S. C., & Clarkson, B. D. (1988) · PubMed · Cited by 58

Philadelphia‐Chromosome Positive Bone‐Marrow Cells Showing Loss of the Y in Males with Chronic Myeloid Leukaemia

Lawler, S. D., Lobb, D., & Wiltshaw, E. (1974) · British Journal of Haematology · doi:10.1111/j.1365-2141.1974.tb06791.x · Cited by 58

Requirement of c-Myb for p210BCR/ABL-dependent transformation of hematopoietic progenitors and leukemogenesis

Lidonnici, M. R., Corradini, F., Waldron, T. J., Bender, T. P., & Calabretta, B. (2008) · Blood · doi:10.1182/blood-2007-08-105072 · Cited by 57

The BCR-ABL1 Kinase Bypasses Selection for the Expression of a Pre–B Cell Receptor in Pre–B Acute Lymphoblastic Leukemia Cells

Klein, F., Feldhahn, N., Harder, L., Wang, H., Wartenberg, M., Hofmann, W., Wernet, P., Siebert, R., & Müschen, M. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031637 · Cited by 57

Sequence-Based Analysis of Translocations and Inversions in Bread Wheat (Triticum aestivum L.)

Ma, J., Stiller, J., Berkman, P. J., Wei, Y., Rogers, J., Feuillet, C., Doležel, J., Mayer, K., Eversole, K., Zheng, Y., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079329 · Cited by 57

BCR-ABL nuclear entrapment kills human CML cells: ex vivo study on 35 patients with the combination of imatinib mesylate and leptomycin B

Aloisi, A., Gregorio, S. D., Stagno, F., Guglielmo, P., Mannino, F., Sormani, M. P., Bruzzi, P., Gambacorti-Passerini, C. B., Saglio, G. N., Venuta, S., et al. (2005) · Blood · doi:10.1182/blood-2005-05-2123 · Cited by 57

Computational analysis of next generation sequencing data and its applications in clinical oncology

Wadapurkar, R. M., & Vyas, R. (2018) · Informatics in Medicine Unlocked · doi:10.1016/j.imu.2018.05.003 · Cited by 60

Detection of minimal residual disease

Dölken, G. (2001) · Advances in cancer research · doi:10.1016/s0065-230x(01)82005-4 · Cited by 57

Comparison of competitive-nested PCR and real-time PCR in detecting BCR-ABL fusion transcripts in chronic myeloid leukemia patients

Guo, J., Lin, H., Kantarjian, H. M., Talpaz, M., Champlin, R. E., Andreeff, M., Glassman, A. B., & Arlinghaus, R. B. (2002) · Leukemia · doi:10.1038/sj.leu.2402730 · Cited by 57

Chronic myelogenous leukemia: Laboratory diagnosis and monitoring

Wang, Y. L., Bagg, A., Pear, W. S., Nowell̀, P. C., & Hess, J. L. (2001) · Genes Chromosomes and Cancer · doi:10.1002/gcc.1171 · Cited by 57

Philadelphia positive acute lymphoblastic leukaemia of childhood

Jones, L. K., & Saha, V. (2005) · British Journal of Haematology · doi:10.1111/j.1365-2141.2005.05611.x · Cited by 57

Hematologic Disease Induced in BALB/c Mice by a bcr-abl Retrovirus Is Influenced by the Infection Conditions

Elefanty, A. G., & Cory, S. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.4.1755 · Cited by 57

Significance of chromosome change to hematopoietic neoplasms

CHAGANTI, R. S. K. (1983) · Blood · doi:10.1182/blood.v62.3.515.515 · Cited by 57

Mapping of four distinct BCR-related loci to chromosome region 22q11: order of BCR loci relative to chronic myelogenous leukemia and acute lymphoblastic leukemia breakpoints.

Croce, C. M., Huebner, K., Isobe, M., Fainstain, E., Lifshitz, B., Shtivelman, E., & Canaani, E. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.20.7174 · Cited by 57

Minimal residual disease in patients with chronic myelogenous leukemia undergoing long-term treatment with recombinant interferon alpha-2b alone or in combination with interferon gamma

Opalka, B., Wandl, U. B., Becher, R., Kloke, O., Nagel‐Hiemke, M., Moritz, T., Beer, U., Seeber, S., & Niederle, N. (1991) · Blood · doi:10.1182/blood.v78.9.2188.2188 · Cited by 57

The specificity of chromosome A2 involvement in DMBA-induced rat sarcomas

Levan, G., Ahlström, U., & Mitelman, F. (2009) · Hereditas · doi:10.1111/j.1601-5223.1974.tb00939.x · Cited by 57

Malignancy and Transformation: Expression in Somatic Cell Hybrids and Variants

Ozer, H. L., & Jha, K. K. (1977) · Advances in cancer research · doi:10.1016/s0065-230x(08)60632-6 · Cited by 57

Next-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us?

Leblanc, V., & Marra, M. A. (2015) · Cancers · doi:10.3390/cancers7030869 · Cited by 57

Common Leukemia- and Lymphoma-Associated Genetic Aberrations in Healthy Individuals

Song, J., Mercer, D., Hu, X., Liu, H., & Li, M. M. (2011) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2010.10.009 · Cited by 57

Dasatinib and nilotinib for imatinib-resistant or -intolerant chronic myeloid leukaemia: a systematic review and economic evaluation.

Rogers, G., Hoyle, M., Coon, J. T., Moxham, T., Liu, Z., Pitt, M., & Stein, K. (2012) · Health Technology Assessment · doi:10.3310/hta16220 · Cited by 56

Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors

Hiwase, D., White, D. L., Powell, J. A., Saunders, V. A., Zrim, S., Frede, A., Guthridge, M. A., Lopez, A. F., D’Andrea, R. J., To, L. B., et al. (2010) · Leukemia · doi:10.1038/leu.2009.299 · Cited by 56

Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation

Stevens, J. B., Abdallah, B. Y., Regan, S. M., Liu, G., Bremer, S. W., Ye, C. J., & Heng, H. H. (2010) · Molecular Cytogenetics · doi:10.1186/1755-8166-3-20 · Cited by 57

Current approach to the treatment of chronic myeloid leukaemia

Pašić, I., & Lipton, J. H. (2017) · Leukemia Research · doi:10.1016/j.leukres.2017.01.005 · Cited by 56

hTERT, the catalytic component of telomerase, is downregulated in the haematopoietic stem cells of patients with chronic myeloid leukaemia

Campbell, L. J., Fidler, C., Eagleton, H., Peniket, A., Kušec, R., Gal, S., Littlewood, T. J., Wainscoat, J. S., & Boultwood, J. (2006) · Leukemia · doi:10.1038/sj.leu.2404141 · Cited by 58

P-loop mutations and novel therapeutic approaches for imatinib failures in chronic myeloid leukemia

Cang, S., & Liu, D. (2008) · Journal of Hematology & Oncology · doi:10.1186/1756-8722-1-15 · Cited by 56

Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene

Le, L. Q., Kabarowski, J. H. S., Wong, S., Nguyen, K., Gambhir, S. S., & Witte, O. N. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00058-2 · Cited by 56

Mathematical model of granulocytopoiesis and chronic myelogenous leukemia.

FOKAS, A. S., Keller, J. B., & Clarkson, B. (1991) · PubMed · Cited by 56

Chronic myeloid leukemia: a model for oncology

Hehlmann, R., Berger, U., & Hochhaus, A. (2005) · Annals of Hematology · doi:10.1007/s00277-005-1039-z · Cited by 56

INVOLVEMENT OF CHROMOSOMES 8, 9, 19 AND 22 IN PH1 POSITIVE AND PH1 NEGATIVE CHRONIC MYELOCYTIC LEUKEMIA IN THE CHRONIC OR BLASTIC STAGE

Gahrton, G., Lindsten, J., & Zech, L. (1974) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1974.tb01024.x · Cited by 56

Chronic Granulocytic Leukemia without the Philadelphia Chromosome

Canellos, G. P., Whang‐Peng, J., & DeVita, V. T. (1976) · American Journal of Clinical Pathology · doi:10.1093/ajcp/65.4.467 · Cited by 56

From cytogenetics to next-generation sequencing technologies: advances in the detection of genome rearrangements in tumorsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.

Morozova, O., & Marra, M. A. (2008) · Biochemistry and Cell Biology · doi:10.1139/o08-003 · Cited by 46

New strategies for targeting kinase networks in cancer

Yesilkanal, A. E., Johnson, G. L., Ramos, A. F., & Rosner, M. R. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.101128 · Cited by 58

Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer

de Oliveira, G. A. P., Rangel, L. P., da Costa, D. C. F., & Silva, J. L. (2015) · Frontiers in Oncology · doi:10.3389/fonc.2015.00097 · Cited by 56

Cytogenetic harvesting of commonly used tumor cell lines

MacLeod, R. A. F., Kaufmann, M., & Drexler, H. G. (2007) · Nature Protocols · doi:10.1038/nprot.2007.29 · Cited by 55

SLC22A1-ABCB1 Haplotype Profiles Predict Imatinib Pharmacokinetics in Asian Patients with Chronic Myeloid Leukemia

Singh, O., Chan, J. Y., Lin, K., Chuah, C. T. H., & Chowbay, B. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051771 · Cited by 55

Resistance in chronic myeloid leukemia: definitions and novel therapeutic agents

Talati, C., & Pinilla-Ibarz, J. A. (2017) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000403 · Cited by 59

Identification of chromosome anomalies in the blastic phase of chronic myelocytic leukemia (CML) by Giemsa- and quinacrine-banding techniques

Hossfeld, D. K. (1974) · Human Genetics · doi:10.1007/bf00282208 · Cited by 26

"Masked" Ph1 chromosome abnormalities in CML: a report of two unique cases

Bernstein, R., Pinto, M., Rosendorff, J., Kramer, S., & Mendelow, B. (1984) · Blood · doi:10.1182/blood.v63.2.399.399 · Cited by 12

A Unique, Complex Variant Philadelphia Chromosome Translocation in a Patient With Typical Chronic Myelogenous Leukemia

Oudat, R., Khan, Z., & Glassman, A. B. (2001) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2001-125-0437-aucvpc · Cited by 8

Chromosome band analysis in 19 cases of chronic myeloid leukemia: 9 chronic, 10 blastic, two with Ph1 (22q-) translocation on 17 short arm.

Engel, E., Bj, M., Flexner, J. M., & Krantz, S. B. (1975) · PubMed · Cited by 13

Absence of the 9q+chromosome in Ph1 negative chronic myelogenous leukaemia

Rowley, J. D. (1974) · Journal of Medical Genetics · doi:10.1136/jmg.11.2.166 · Cited by 15