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Correlation of IR spectroscopic, heat capacity, diamagnetic susceptibility and enzymatic measurements on lysozyme powder
Open accessAbstract
The interaction between protein and water is of fundamental importance for processes ranging from protein folding and enzymatic activity1 to anhydrobiosis2. In this letter we bring together results from diverse types of measurements to give a unified picture of the hydration process for lysozyme. The data come principally from experiments with protein films and powders. The principal aim is to examine the relationship between the sites of water interaction, the extent of coverage, and the enzymatic activity, thus providing a better understanding of the relationship between water and enzyme dynamics3.
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Cited by
An infrared spectroscopic study of the interactions of carbohydrates with dried proteins
Carpenter, J. F., & Crowe, J. H. (1989) · Biochemistry · doi:10.1021/bi00435a044 · Cited by 758
A unified model of protein dynamics
Frauenfelder, H., Chen, G., Berendzen, J., Fenimore, P. W., Jansson, H., McMahon, B. H., Stroe, I. R., Swenson, J., & Young, R. D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900336106 · Cited by 757
Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers
Prestrelski, S. J., Tedeschi, N., Arakawa, T., & Carpenter, J. F. (1993) · Biophysical Journal · doi:10.1016/s0006-3495(93)81120-2 · Cited by 718
Soares, C. M., Teixeira, V. H., & Baptista, A. M. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74972-8 · Cited by 149
The molecular basis for hydrodynamic properties of PEGylated human serum albumin
(2024) · doi:10.1016/j.bpj.2024.05.019 · Cited by 9
Metadata
- Authors
- Careri, G., Gratton, E., Yang, P.-H., & Rupley, J. A.
- Venue
- Nature
- Published
- 1980-04
- Volume
- 284
- Issue
- 5756
- Pages
- 572-573
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2079364658
- Cited by
- 198
- References
- 0
- FWCI
- 1.74
- Type
- journal article
- Language
- en
- Open access
- green
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- Careri, G., Gratton, E., Yang, P.-H., & Rupley, J. A. (1980). Correlation of IR spectroscopic, heat capacity, diamagnetic susceptibility and enzymatic measurements on lysozyme powder. Nature. https://doi.org/10.1038/284572a0
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