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Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos
Open accessAbstract
The expression of theXenopus homoeobox gene xhox3 is an early response to mesoderm induction by peptide growth factors and the level of xhox3 expression marks the antero-posterior character of the induced mesoderm. Different peptide growth factors specify different antero-posterior mesodermal cell fates as seen by the level of xhox3 expression and the capacity to induce specific secondary neural/epidermal structures. These factors and homoeobox genes thus form part of the mechanism necessary for establishing antero-posterior polarity in the frog embryo.
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Citations
Cited by
Amaya, E., Musci, T. J., & Kirschner, M. W. (1991) · Cell · doi:10.1016/0092-8674(91)90616-7 · Cited by 1,085
MyoD family: a paradigm for development?
Olson, E. N. (1990) · Genes & Development · doi:10.1101/gad.4.9.1454 · Cited by 734
How embryos work: a comparative view of diverse modes of cell fate specification
Davidson, E. H. (1990) · Development · doi:10.1242/dev.108.3.365 · Cited by 267
Spatial mechanisms of gene regulation in metazoan embryos
Davidson, E. H. (1991) · Development · doi:10.1242/dev.113.1.1 · Cited by 233
Metadata
- Authors
- i Altaba, A. R., & Melton, D. A.
- Venue
- Nature
- Published
- 1989-09
- Volume
- 341
- Issue
- 6237
- Pages
- 33-38
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1970341768
- Cited by
- 257
- References
- 0
- FWCI
- 15.62
- Type
- journal article
- Language
- en
- Open access
- green
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- i Altaba, A. R., & Melton, D. A. (1989). Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos. Nature. https://doi.org/10.1038/341033a0
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