Amplification of a gene encoding a p53-associated protein in human sarcomas

Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L., Vogelstein, B.·1992·Nature

Cited by (1,001)

Items 801–900 of 1,001

  1. The MDM2 RING Domain and Central Acidic Domain Play Distinct Roles in MDM2 Protein Homodimerization and MDM2-MDMX Protein Heterodimerization
    Patrick L. Leslie, Hengming Ke, Yanping Zhang · 2015 · Journal of Biological Chemistry
  2. Organocatalytic, Diastereo- and Enantioselective Synthesis of Nonsymmetric cis -Stilbene Diamines: A Platform for the Preparation of Single-Enantiomer cis -Imidazolines for Protein–Protein Inhibition
    Brandon Vara, Anand Mayasundari, John C. Tellis, Michael W. Danneman, Vanessa Arredondo, Tyler A. Davis, Jaeki Min, Kristin E. Finch, Rodney Kiplin Guy, Jeffrey N. Johnston · 2014 · The Journal of Organic Chemistry
  3. A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop
    Lei Xiong, Fei Kou, Ying Yang, Jiarui Wu · 2007 · The Journal of Cell Biology
  4. GLI gene expression in bone and soft tissue sarcomas of adult patients correlates with tumor grade.
    Ulrike Stein, Christiane Eder, Uwe R. Karsten, Wolfgang Haensch, Wolfgang Walther, Peter M. Schlag · 1999 · PubMed
  5. Merkel cells in the human oesophagus
    J. L. Harmse, Francis A. Carey, A. Baird, S. Craig, K. N. Christie, D. Hopwood, John M. Lucocq · 1999 · Journal of Pathology
  6. Distinct Angiogenic patterns are associated with high-gradein situ ductal carcinomas of the breast
    Knut Engels, Stephen B. Fox, Ruth M. Whitehouse, Kevin C. Gatter, Adrian Llewellyn Harris · 1997 · The Journal of Pathology
  7. Transfection of Rat Embryo Cells with Mutant p53 Increases the Intrinsic Radiation Resistance
    Francisco S. Pardo, Mei Su, Carmia G. Borek, F I Preffer, David Dombkowski, Leo E. Gerweck, Emmett V. Schmidt · 1994 · Radiation Research
  8. Association of overexpression of p53 oncoprotein with the state of cell proliferation in oral carcinoma
    Saman Warnakulasuriya, Newell Walter Johnson · 1994 · Journal of Oral Pathology and Medicine
  9. p53: DNA damage, DNA repair, and apoptosis
    Claudia Götz, Mathias Montenarh · 1995 · Reviews of physiology, biochemistry and pharmacology
  10. A Small-Molecule p53 Activator Induces Apoptosis through Inhibiting MDMX Expression in Breast Cancer Cells
    Hongbo Wang, Chunhong Yan · 2011 · Neoplasia
  11. Aciculatin Induces p53-Dependent Apoptosis via MDM2 Depletion in Human Cancer Cells In Vitro and In Vivo
    Chin-Yu Lai, An-Chi Tsai, Mei-Chuan Chen, Li-Hsun Chang, Hui‐Lung Sun, Ya-Ling Chang, Chien-Chih Chen, Che‐Ming Teng, Shiow‐Lin Pan · 2012 · PLoS ONE
  12. The Ubiquitin-interacting Motif Protein, S5a, Is Ubiquitinated by All Types of Ubiquitin Ligases by a Mechanism Different from Typical Substrate Recognition
    Tomoaki Uchiki, Hyoung Tae Kim, Bo Zhai, Steven P. Gygi, Jennifer A. Johnston, John P. O’Bryan, Alfred Lewis Goldberg · 2009 · Journal of Biological Chemistry
  13. SNP285C modulates oestrogen receptor/Sp1 binding to the MDM2 promoter and reduces the risk of endometrial but not prostatic cancer
    Stian Knappskog, Jone Trovik, Janusz Marcickiewicz, Solveig Tingulstad, Annetine Staff, Pål Romundstad, Kristian Hveem, LARS JOHAN VATTEN, Helga Birgitte Salvesen, Per Eystein Lønning · 2011 · European Journal of Cancer
  14. Recent Advances in Validating MDM2 as a Cancer Target
    Elizabeth R. Rayburn, Scharri J. Ezell, Ruiwen Zhang · 2009 · Anti-Cancer Agents in Medicinal Chemistry
  15. Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins
    Hirotaka Takahashi, Atsushi Uematsu, Satoshi Yamanaka, Mei Imamura, Tatsuro Nakajima, Kousuke Doi, Saki Yasuoka, Chikako Takahashi, Hiroyuki Takeda, Tatsuya Sawasaki · 2016 · PLoS ONE
  16. MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA
    Anna Phillips, Jeremy P. Blaydes · 2007 · Oncogene
  17. Amplification of multiple regions of chromosome 12, including 12q13–15, in chronic lymphocytic leukaemia
    Mats Merup, Gunnar Juliusson, Xiushan Wu, Monika Jansson, Birgitta Stellan, Omid Rasool, Eva Röijer, Göran Stenman, Gösta Gahrton, Stefan Einhorn · 1997 · European Journal Of Haematology
  18. Interphase Cytogenetic Analysis of Solid Tumors by Non-Isotopic DNA in situ Hybridization
    Janneke C. Alers, Herman van Dekken · 1996 · Progress in Histochemistry and Cytochemistry
  19. Linkage studies in a Li-Fraumeni family with increased expression of p53 protein but no germline mutation in p53
    Jillian M. Birch, Jim Heighway, M. Dawn Teare, Anna M. Kelsey, Ann L. Hartley, Karen J Tricker, Derek Crowther, David Philip Lane, Mauro Santibanez‐Koref · 1994 · British Journal of Cancer
  20. Supramolecular Complex Formation between Rad6 and Proteins of the p53 Pathway during DNA Damage-Induced Response
    Alex Lyakhovich, Malathy P.V. Shekhar · 2003 · Molecular and Cellular Biology
  21. Conditionally Replicating Adenoviruses for Cancer Treatment
    Youssef Jounaïdi, Joshua C. Doloff, David J. Waxman · 2007 · Current Cancer Drug Targets
  22. Association of Polymorphism in MDM-2 and p53 Genes with Breast Cancer Risk in Indian Women
    Virendra Kumar Singh, Neeraj Rastogi, Neeraj Mathur, Kalpana Singh, Mahendra Pratap Singh · 2007 · Annals of Epidemiology
  23. Metal and RNA Binding Properties of the hdm2 RING Finger Domain
    Zhihong Lai, Deborah A. Freedman, Arnold J. Levine, George L McLendon · 1998 · Biochemistry
  24. Analysis of p53 mutational events and MDM2 amplification in canine soft-tissue sarcomas
    L. Nasir, Gerard R. Rutteman, S. W. J. Reid, Ch. Schulze, D. J. Argyle · 2001 · Cancer Letters
  25. Combined Targeting of Epidermal Growth Factor Receptor and MDM2 by Gefitinib and Antisense MDM2 Cooperatively Inhibit Hormone-Independent Prostate Cancer
    Roberto Bianco, Roberta Caputo, Rosa Caputo, Vincenzo Damiano, Sabino De Placido, Corrado Ficorella, Sudhir Agrawal, A R Bianco, Fortunato Ciardiello, Giampaolo Tortora · 2004 · Clinical Cancer Research
  26. Geldanamycin Prevents Nuclear Translocation of Mutant p53
    Gargi Dasgupta, Jamil Antonio Momand · 1997 · Experimental Cell Research
  27. Exploring the Genetic Orchestra of Cancer: The Interplay Between Oncogenes and Tumor-Suppressor Genes
    S. P. Singh, Rakesh Bhaskar, Shampa Ghosh, Bhuvaneshwar Yarlagadda, Dr. Krishna Kumar Singh, Prashant Verma, Sonali Sengupta, Mitko I. Mladenov, Nikola Hadzi‐Petrushev, Radoslav Stojchevski et al. · 2025 · Cancers
  28. Molecular analysis of p53, MDM2 and H-ras genes in low-grade central osteosarcoma
    Hye‐Rim Park, Woon Won Jung, Franco Bertoni, Patrizia Bacchini, Jae Hoon Park, Youn-Wha Kim, Yong-Koo Park · 2004 · Pathology - Research and Practice
  29. Human Papillomavirus Seropositivity Synergizes withMDM2Variants to Increase the Risk of Oral Squamous Cell Carcinoma
    Xingming Chen, Erich M. Sturgis, Dapeng Lei, Kristina R. Dahlstrom, Qingyi Wei, Guojun Li · 2010 · Cancer Research
  30. Redirection of T Cells by Delivering a Transgenic Mouse-Derived MDM2 Tumor Antigen-Specific TCR and its Humanized Derviative Is Governed by the CD8 Coreceptor and Affects Natural Human TCR Expression
    Ralf-Holger Voss, Jurgen H. E. Kuball, Renate Engel, Philippe Guillaume, Pedro J. Romero, Christoph Huber, Matthias Theobald · 2006 · Immunologic Research
  31. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis
    Cen Zhang, Juan Liu, Chunwen Tan, Xuetian Yue, Yuhan Zhao, Jiaping Peng, Xiaolong Wang, Saurabh V. Laddha, Chang S. Chan, Shu Sen Zheng et al. · 2016 · Oncotarget
  32. Induction of 18A2/mts1 Gene Expression and Its Effects on Metastasis and Cell Cycle Control
    C. Parker, P.A. WHITTAKER, Badar A. Usmani, M.S. Lakshmi, Gajanan V. Sherbet · 1994 · DNA and Cell Biology
  33. IFN Regulatory Factor 8 Regulates MDM2 in Germinal Center B Cells
    Zhou, Jeff X, Lee, Chang Hoon, Qi, Chen Feng, Wang, Hongsheng, Naghashfar, Zohreh, Abbasi, Sadia, Morse, Herbert C · 2009 · The Journal of Immunology
  34. MDM2-p53 protein–protein interaction inhibitors: A-ring substituted isoindolinones
    Anna F. Watson, Junfeng Liu, Karim Bennaceur, Catherine J. Drummond, Jane Endicott, Bernard T. Golding, Roger J. Griffin, Karen Haggerty, Xiaohong Lü, James M. McDonnell et al. · 2011 · Bioorganic & Medicinal Chemistry Letters
  35. Mdm2 and the p53 pathway in human pituitary adenomas
    Mohamed Suliman, Janice A. Royds, D. R. Cullen, WALTER R. TIMPERLEY, Tom Powell, Robert D. E. Battersby, T. Hugh Jones · 2001 · Clinical Endocrinology
  36. Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites
    Cristina Bartocci, Eros Lazzerini Denchi · 2013 · Frontiers in Genetics
  37. CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies
    Long Jiang, Katrine Ingelshed, Yunbing Shen, Sanjaykumar V. Boddul, Vaishnavi Srinivasan Iyer, Zsolt Kasza, Saikiran K. Sedimbi, David Philip Lane, Fredrik Wermeling · 2021 · Cancer Research
  38. Involvement ofINK4A gene products in the pathogenesis and development of human osteosarcoma
    M. S. Benassi, Lara Molendini, Gabriella Gamberi, Giovanna Magagnoli, Paola Ragazzini, Giuliana Gobbi, Luca Sangiorgi, Laura Pazzaglia, Julia Asp, Camilla Brantsing et al. · 2001 · Cancer
  39. Myxoinflammatory fibroblastic sarcoma with complex supernumerary ring chromosomes composed of chromosome 3 segments
    Atiya Mansoor, Nisreen Fidda, Eleanor Himoe, Misty Payne, Helen J. Lawce, R. Ellen Magenis · 2004 · Cancer Genetics and Cytogenetics
  40. p53 and MDM2 expression in odontogenic cysts and tumours
    Júnia Noronha Carvalhais, MCF. Aguiar, Vera Cavalcanti de Araújo, NS de Araújo, Ricardo Santiago Gomez · 1999 · Oral Diseases
  41. Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP
    Nadine Van Roy, Anne Forus, Ola Myklebost, Ngan Ching Cheng, Rogier Versteeg, Frank Speleman · 1995 · Cancer Genetics and Cytogenetics
  42. On the expression of the p53 protein in human cancer
    David Philip Lane · 1994 · Molecular Biology Reports
  43. NOLC1, an Enhancer of Nasopharyngeal Carcinoma Progression, Is Essential for TP53 to Regulate MDM2 Expression
    Yu-Chyi Hwang, Tung‐Ying Lu, Dah‐Yeou Huang, Yuan‐Sung Kuo, Cheng-Fu Kao, Ning-Hsing Yeh, Han‐Chung Wu, Chin‐Tarng Lin · 2009 · American Journal Of Pathology
  44. Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
    Elena Tamborini, Gabriella Della Torre, Cinzia Emilia Lavarino, Alberto Azzarelli, Patrizia Carpinelli, Marco Alessandro Pierotti, Silvana Pilotti · 2001 · International Journal of Cancer
  45. Mdm2 and Tumorigenesis: Evolving Theories and Unsolved Mysteries
    E. Senturk, James J. Manfredi · 2012 · Genes & Cancer
  46. A p53 dose-response relationship for sensitivity to DNA damage in isogenic teratocarcinoma cells
    Stuart G. Lutzker, Robin Mathew, Derek R Taller · 2001 · Oncogene
  47. NO and transcriptional regulation: from signaling to death
    Jie Zhou, Bernhard Brüne · 2004 · Toxicology
  48. On the regulation of the p53 tumour suppressor, and its role in the cellular response to DNA damage
    David Philip Lane, Carol Midgley, Ted R. Hupp, Xin Lü, Bořivoj Vojtěšek, Steven M. Picksley · 1995 · Philosophical Transactions of the Royal Society B Biological Sciences
  49. Expression of p53, MDM2 protein and Ki-67 antigen in recurrent meningiomas
    Mitsuaki Ohkoudo, Hiroki Sawa, Mitsuhiro Hara, Kazuhiko Saruta, Toshiko Aiso, Reiko Ohki, Hiroshi Yamamoto, Eiji Maemura, Yoshio SHIINA, Masahiko Fujii et al. · 1998 · Journal of Neuro-Oncology
  50. REVIEW ARTICLE. p53: GUARDIAN OF CELLULAR SENESCENCE
    David Wynford‐Thomas · 1996 · The Journal of Pathology
  51. Establishment of a cell line with variantBCR/ABL breakpoint expressing P180BCR/ABL from late-appearing Philadelphia-positive acute biphenotypic leukemia
    Koiti Inokuchi, Tamiko Shinohara, Makoto Futaki, Hideki Hanawa, Sakae Tanosaki, Hiroki Yamaguchi, Takeo Nomura, Kazuo Dan · 1998 · Genes Chromosomes and Cancer
  52. Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells
    S Singh, Mahesh Ramamoorthy, Catherine A. Vaughan, William Andrew Yeudall, Sumitra Deb, Sumitra Deb · 2012 · Cell Death and Differentiation
  53. Gene abnormalities in multiple myeloma; the relevance of TP53, MDM2, and CDKN2A.
    Manal O. Elnenaei, Alicja Gruszka, Roger A'Hernt, Estella Matutes, Bhawna Sirohi, R Powles, Daniel Catovsky · 2003 · PubMed
  54. Amplification and Overexpression of mdm2 Gene in Ependymomas
    Satoshi O. Suzuki, Toru Iwaki · 2000 · Modern Pathology
  55. Overexpression of MDM2 oncoprotein correlates with possession of estrogen receptor alpha and lack of MDM2 mRNA splice variants in human breast cancer
    Masao Hori, Jiro Shimazaki, Satoshi Inagawa, Masayuki Itabashi, Mitsuo Hori · 2002 · Breast Cancer Research and Treatment
  56. (R)-Roscovitine (CYC202, Seliciclib) sensitizes SH-SY5Y neuroblastoma cells to nutlin-3-induced apoptosis
    Judit Ribas, Jacint Boix, Laurent Meijer · 2006 · Experimental Cell Research
  57. Amplification of 12q13 and 12q15 Sequences in a Sclerosing Epithelioid Fibrosarcoma
    David Gisselsson, Patrik Andreasson, Jeanne M. Meis‐Kindblom, Lars‐Gunnar Kindblom, Fredrik Mertens, Nils Mandahl · 1998 · Cancer Genetics and Cytogenetics
  58. Immunocytochemical analysis of the tumour suppressor protein (p53) in feline neoplasia
    Lubna Nasir, Hilary Krasner, David J. Argyle, Alun Williams · 2000 · Cancer Letters
  59. Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster
    Chengzhen Ren, Cheng Hui Ren, Likun Li, Alexei A. Goltsov, Timothy C. Thompson · 2006 · Genomics
  60. Function and dysfunction of the human oncoprotein MDM2
    Swati Palit Deb · 2002 · Frontiers in bioscience
  61. Worrying about p53
    David Philip Lane · 1992 · Current Biology
  62. Abnormal expression of the p53-binding protein MDM2 in Hodgkin's disease
    Marco Chilosi, Claudio Doglioni, Fabio Menestrina, Licia Montagna, Antonella Rigo, Maurizio Lestani, Mattia Barbareschi, Aldo Scarpa, GM Mariuzzi, Giovanni Pizzolo · 1994 · Blood
  63. p53 Protein Detected By Immunohistochemical Staining is Not Always Mutant
    Catriona MacGeoch, Diana M. Barnes, Julia A. Newton, Shehla N. Mohammed, Shirley Victoria Hodgson, Mun Hon Ng, David Timothy Bishop, Nigel K. Spurr · 1993 · Disease Markers
  64. Activation of the human immunodeficiency virus type 1 long terminal repeat by transforming mutants of human p53
    Mark A. Subler, Daniel W. Martin, Sumitra Deb · 1994 · Journal of Virology
  65. Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.
    Jeffrey M. Jones, Laura Donatella Attardi, Lucy A. Godley, Rodolfo Laucirica, Daniel Medina, Tyler Jacks, HAROLD E. VARMUS, Lawrence A. Donehower · 1997 · PubMed
  66. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation
    Zheng-Cheng Yu, Yi‐Fu Huang, Sheau-Yann Shieh · 2015 · Nucleic Acids Research
  67. Overexpression of MDM2 protein in intrahepatic cholangiocarcinoma: relationship with p53 overexpression, Ki-67 labeling, and clinicopathological features
    Satoshi Horie, Kanenori Endo, Hironaka Kawasaki, Tadashi Terada · 2000 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  68. Lysine methylation represses p53 activity in teratocarcinoma cancer cells
    Jiajun Zhu, Zhixun Dou, Morgan A. Sammons, Arnold J. Levine, Shelley L. Berger · 2016 · Proceedings of the National Academy of Sciences
  69. Molecular biology of gliomas
    Andrew B. Lassman · 2004 · Current Neurology and Neuroscience Reports
  70. Malignant fibrous histiocytoma of bone: Analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry
    Maija Tarkkanen, Marcelo Luis Larramendy, Tom Böhling, Massimo Serra, Claudia Maria Hattinger, Aarne Kivioja, Inkeri Elomaa, Piero Picci, Sakari Knuutila · 2006 · European Journal of Cancer
  71. Stabilization and Activation of p53 by the Coactivator Protein TAFII31
    Thomas Buschmann, Yahong Lin, Nadia Aithmitti, Serge Yu. Fuchs, Hua Lu, Lois Resnick‐Silverman, James J. Manfredi, Ze’ev A. Ronai, Xiangwei Wu · 2001 · Journal of Biological Chemistry
  72. DisruptingTP53 in mouse models of human cancers
    John M. Parant, Guillermina Lozano · 2003 · Human Mutation
  73. Amplification and protein expression of chromosome 12q13-15 genes in osteosarcomas of the jaws
    Márcio Ajudarte Lopes, Nikolaos G. Nikitakis, R.A. Ord, John J. Sauk · 2001 · Oral Oncology
  74. Multiple Murine Double Minute Gene 2 (MDM2) Proteins Are Induced by Ultraviolet Light
    Leslie J. Saucedo, Cena D. Myers, Mary Ellen Perry · 1999 · Journal of Biological Chemistry
  75. Molecular characterization of CD30+ anaplastic large-cell lymphoma: high frequency of c-myc proto-oncogene activation
    Giorgio Inghirami, L Macri, Ethel Cesarman, Amy Chadburn, J Zhong, DM Knowles · 1994 · Blood
  76. A Novel Functional Polymorphism C1797G in the MDM2 Promoter Is Associated with Risk of Bladder Cancer in a Chinese Population
    Meilin Wang, Zhizhong Zhang, Haixia Zhu, Guangbo Fu, Shouyu Wang, Dongmei Wu, Jianwei Zhou, Qingyi Wei, Zhengdong Zhang · 2008 · Clinical Cancer Research
  77. Future of Clinical Genomics in Pediatric Oncology
    Katherine A. Janeway, Andrew E. Place, Mark W. Kieran, Marian H. Harris · 2013 · Journal of Clinical Oncology
  78. Prevalence of MDM2 amplification and coalterations in 523 advanced cancer patients in the MD Anderson phase 1 clinic
    Vikas Dembla, Neeta Somaiah, Pedro Coelho Barata, Kenneth R. Hess, Siqing Fu, Filip Jankú, Daniel D. Karp, Aung Naing, Sarina Anne Piha-Paul, Vivek Subbiah et al. · 2018 · Oncotarget
  79. Role of MDM2 Overexpression in Doxorubicin Resistance of Breast Carcinoma
    Akio Suzuki, Masakazu Toi, Yutaka Yamamoto, Shigehira Saji, Mariko Muta, Takeshi Tominaga · 1998 · Japanese Journal of Cancer Research
  80. p53 protein expression in nephroblastomas: a predictor of poor prognosis
    Dhirendra Govender, P Harilal, G. P. Hadley, Runjan Chetty · 1998 · British Journal of Cancer
  81. Cellular adhesion regulates p53 protein levels in primary human keratinocytes.
    Janice M. Nigro, Kenneth Aldape, Suzanne M. Hess, Thea Dorothy Tlsty · 1997 · PubMed
  82. Posttransplant skin cancer: A possible role for p53 gene mutation but not for oncogenic human papillomaviruses
    Jane McGregor, Alan Farthing, Tim Crook, Carmen C. -W. Yu, Edwin A. Dublin, David A. Levison, D.M. MACDONALD · 1994 · Journal of the American Academy of Dermatology
  83. t(12;22)(q13;q13) and trisomy 8 are nonrandom aberrations in clear-cell sarcoma
    Eduardo Rodrı́guez, Chandrika Sreekantaiah, Victor E. Reuter, Robert John Motzer, Raju S. K. Chaganti · 1992 · Cancer Genetics and Cytogenetics
  84. Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization
    Agnès Marchio, Mounira Meddeb, Pascal Pineau, Gisèle Danglot, Pierre Tiollais, Alain Bernheim, Anne Dejean · 1997 · Genes Chromosomes and Cancer
  85. Transfection of wild-type but not mutant p53 induces early monocytic differentiation in HL60 cells and increases their sensitivity to stress.
    Debashmita Banerjee, H.J. Lenz, Barbara Schnieders, D J Manno, Jingfang Ju, Colin Paul Spears, Daniel Hochhauser, Kathleen D. Danenberg, P. V. Danenberg, J R Bertino · 1995 · PubMed
  86. Discovery of DS-5272 as a promising candidate: A potent and orally active p53–MDM2 interaction inhibitor
    Masaki Miyazaki, Kouichi Uoto, Yuuichi Sugimoto, Hiroyuki Naito, Keisuke Yoshida, Tooru Okayama, Haruko C. Kawato, Masaya Miyazaki, Mayumi Kitagawa, Takahiko Seki et al. · 2015 · Bioorganic & Medicinal Chemistry
  87. Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma
    Hege Oma Ohnstad, Russell Castro, Jinchang Sun, Karen‐Marie Heintz, Lyubomir T. Vassilev, Bodil Bjerkehagen, Stine H. Kresse, Leonardo A. Meza‐Zepeda, Ola Myklebost · 2012 · Cancer
  88. Improvement of the synthesis and pharmacokinetic properties of chromenotriazolopyrimidine MDM2-p53 protein-protein inhibitors
    Hilary P. Beck, Michael R. DeGraffenreid, Brian M. Fox, John G. Allen, Yosup Rew, Stephen Schneider, Anne Y. Saiki, Dongyin Yu, Jonathan D. Oliner, Kevin L. Salyers et al. · 2010 · Bioorganic & Medicinal Chemistry Letters
  89. Design, Synthesis, Chemical and Biochemical Insights Into Novel Hybrid Spirooxindole-Based p53-MDM2 Inhibitors With Potential Bcl2 Signaling Attenuation
    Yasmine M. Abdel Aziz, Gehad Lotfy, Mohamed M. Said, El Sayed H. El Ashry, El Sayed H. El Tamany, Saied M. Soliman, Marwa Muhammad Abu-Serie, Mohamed Teleb, Sammer Yousuf B, Alexander S. S. Dömling et al. · 2021 · Frontiers in Chemistry
  90. Localization of the Human Stat6 Gene to Chromosome 12q13.3–q14.1, a Region Implicated in Multiple Solid Tumors
    Bharvin K.R. Patel, Catherine L. Keck, Ryan S. O'Leary, Nicholas C. Popescu, William J. LaRochelle · 1998 · Genomics
  91. Suppression of hypoxia inducible factor-1α (HIF-1α) by YC-1 is dependent on murine double minute 2 (Mdm2)
    Chi Keung Lau, Zhen Fan Yang, Chi Tat Lam, Ka Ho Tam, Ronnie T. P. Poon, Sheung Tat Fan · 2006 · Biochemical and Biophysical Research Communications
  92. TP53 Mutations in Canine Brain Tumors
    Daniel S. York, R. J. Higgins, Richard A. LeCouteur, ALLAN WOLFE, Robert A. Grahn, Natasha J. Olby, M. Campbell, Peter J. Dickinson · 2011 · Veterinary Pathology
  93. p53 alterations in recurrent squamous cell cancer of the head and neck refractory to radiotherapy
    Ian Ganly, David S. Soutar, Robert Eldon Brown, Stuart B. Kaye · 2000 · British Journal of Cancer
  94. Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers
    E. Copson, H. White, J. Blaydes, D. Robinson, Peter W. M. Johnson, D. Eccles · 2006 · BMC Cancer
  95. MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8+ autologous T lymphocytes
    Christine Mayr, Dagmar Bund, Martin Schlee, Martina Bamberger, David M. Kofler, Michael J. Hallek, Clemens‐Martin Wendtner · 2006 · Experimental Hematology
  96. Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations
    Β. Michael Ghadimi, Dan L. Sackett, Michael J. Difilippantonio, Evelin Schr�ck, Thomas Neumann, Annukka Jauho, Gert Auer, Thomas Ried · 2000 · Genes Chromosomes and Cancer
  97. Low grade fibromyxoid sarcoma
    Alessandra Mezzelani, Gabriella Sozzi, Michelle Neßling, Carla Riva, Gabriella Della Torre, M. Testi, Alberto Azzarelli, Marco Alessandro Pierotti, Peter Lichter, Silvana Pilotti · 2000 · Cancer Genetics and Cytogenetics
  98. Phosphorylation Studies on Rat p53 Using the Baculovirus Expression System
    Bergund Fuchs, Doris Hecker, Karl Heinz Scheidtmann · 1995 · European Journal of Biochemistry
  99. Analysis of the p16INK4 and TP53 tumor suppressor genes in bone sarcoma pediatric patients
    Ana Patiño‐García, Luis Sierrasesúmaga · 1997 · Cancer Genetics and Cytogenetics
  100. The Tumor Suppressor ING1: Structure and Function
    K.-John Cheung, Gang Li · 2001 · Experimental Cell Research