Amplification of a gene encoding a p53-associated protein in human sarcomas
Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L., Vogelstein, B.·1992·Nature
DOI 10.1038/358080a0
Cited by (1,001)
Items 801–900 of 1,001
- The MDM2 RING Domain and Central Acidic Domain Play Distinct Roles in MDM2 Protein Homodimerization and MDM2-MDMX Protein HeterodimerizationPatrick L. Leslie, Hengming Ke, Yanping Zhang · 2015 · Journal of Biological Chemistry
- Organocatalytic, Diastereo- and Enantioselective Synthesis of Nonsymmetric cis -Stilbene Diamines: A Platform for the Preparation of Single-Enantiomer cis -Imidazolines for Protein–Protein InhibitionBrandon Vara, Anand Mayasundari, John C. Tellis, Michael W. Danneman, Vanessa Arredondo, Tyler A. Davis, Jaeki Min, Kristin E. Finch, Rodney Kiplin Guy, Jeffrey N. Johnston · 2014 · The Journal of Organic Chemistry
- A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loopLei Xiong, Fei Kou, Ying Yang, Jiarui Wu · 2007 · The Journal of Cell Biology
- GLI gene expression in bone and soft tissue sarcomas of adult patients correlates with tumor grade.Ulrike Stein, Christiane Eder, Uwe R. Karsten, Wolfgang Haensch, Wolfgang Walther, Peter M. Schlag · 1999 · PubMed
- Merkel cells in the human oesophagusJ. L. Harmse, Francis A. Carey, A. Baird, S. Craig, K. N. Christie, D. Hopwood, John M. Lucocq · 1999 · Journal of Pathology
- Distinct Angiogenic patterns are associated with high-gradein situ ductal carcinomas of the breastKnut Engels, Stephen B. Fox, Ruth M. Whitehouse, Kevin C. Gatter, Adrian Llewellyn Harris · 1997 · The Journal of Pathology
- Transfection of Rat Embryo Cells with Mutant p53 Increases the Intrinsic Radiation ResistanceFrancisco S. Pardo, Mei Su, Carmia G. Borek, F I Preffer, David Dombkowski, Leo E. Gerweck, Emmett V. Schmidt · 1994 · Radiation Research
- Association of overexpression of p53 oncoprotein with the state of cell proliferation in oral carcinomaSaman Warnakulasuriya, Newell Walter Johnson · 1994 · Journal of Oral Pathology and Medicine
- p53: DNA damage, DNA repair, and apoptosisClaudia Götz, Mathias Montenarh · 1995 · Reviews of physiology, biochemistry and pharmacology
- A Small-Molecule p53 Activator Induces Apoptosis through Inhibiting MDMX Expression in Breast Cancer CellsHongbo Wang, Chunhong Yan · 2011 · Neoplasia
- Aciculatin Induces p53-Dependent Apoptosis via MDM2 Depletion in Human Cancer Cells In Vitro and In VivoChin-Yu Lai, An-Chi Tsai, Mei-Chuan Chen, Li-Hsun Chang, Hui‐Lung Sun, Ya-Ling Chang, Chien-Chih Chen, Che‐Ming Teng, Shiow‐Lin Pan · 2012 · PLoS ONE
- The Ubiquitin-interacting Motif Protein, S5a, Is Ubiquitinated by All Types of Ubiquitin Ligases by a Mechanism Different from Typical Substrate RecognitionTomoaki Uchiki, Hyoung Tae Kim, Bo Zhai, Steven P. Gygi, Jennifer A. Johnston, John P. O’Bryan, Alfred Lewis Goldberg · 2009 · Journal of Biological Chemistry
- SNP285C modulates oestrogen receptor/Sp1 binding to the MDM2 promoter and reduces the risk of endometrial but not prostatic cancerStian Knappskog, Jone Trovik, Janusz Marcickiewicz, Solveig Tingulstad, Annetine Staff, Pål Romundstad, Kristian Hveem, LARS JOHAN VATTEN, Helga Birgitte Salvesen, Per Eystein Lønning · 2011 · European Journal of Cancer
- Recent Advances in Validating MDM2 as a Cancer TargetElizabeth R. Rayburn, Scharri J. Ezell, Ruiwen Zhang · 2009 · Anti-Cancer Agents in Medicinal Chemistry
- Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate ProteinsHirotaka Takahashi, Atsushi Uematsu, Satoshi Yamanaka, Mei Imamura, Tatsuro Nakajima, Kousuke Doi, Saki Yasuoka, Chikako Takahashi, Hiroyuki Takeda, Tatsuya Sawasaki · 2016 · PLoS ONE
- MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNAAnna Phillips, Jeremy P. Blaydes · 2007 · Oncogene
- Amplification of multiple regions of chromosome 12, including 12q13–15, in chronic lymphocytic leukaemiaMats Merup, Gunnar Juliusson, Xiushan Wu, Monika Jansson, Birgitta Stellan, Omid Rasool, Eva Röijer, Göran Stenman, Gösta Gahrton, Stefan Einhorn · 1997 · European Journal Of Haematology
- Interphase Cytogenetic Analysis of Solid Tumors by Non-Isotopic DNA in situ HybridizationJanneke C. Alers, Herman van Dekken · 1996 · Progress in Histochemistry and Cytochemistry
- Linkage studies in a Li-Fraumeni family with increased expression of p53 protein but no germline mutation in p53Jillian M. Birch, Jim Heighway, M. Dawn Teare, Anna M. Kelsey, Ann L. Hartley, Karen J Tricker, Derek Crowther, David Philip Lane, Mauro Santibanez‐Koref · 1994 · British Journal of Cancer
- Supramolecular Complex Formation between Rad6 and Proteins of the p53 Pathway during DNA Damage-Induced ResponseAlex Lyakhovich, Malathy P.V. Shekhar · 2003 · Molecular and Cellular Biology
- Conditionally Replicating Adenoviruses for Cancer TreatmentYoussef Jounaïdi, Joshua C. Doloff, David J. Waxman · 2007 · Current Cancer Drug Targets
- Association of Polymorphism in MDM-2 and p53 Genes with Breast Cancer Risk in Indian WomenVirendra Kumar Singh, Neeraj Rastogi, Neeraj Mathur, Kalpana Singh, Mahendra Pratap Singh · 2007 · Annals of Epidemiology
- Metal and RNA Binding Properties of the hdm2 RING Finger DomainZhihong Lai, Deborah A. Freedman, Arnold J. Levine, George L McLendon · 1998 · Biochemistry
- Analysis of p53 mutational events and MDM2 amplification in canine soft-tissue sarcomasL. Nasir, Gerard R. Rutteman, S. W. J. Reid, Ch. Schulze, D. J. Argyle · 2001 · Cancer Letters
- Combined Targeting of Epidermal Growth Factor Receptor and MDM2 by Gefitinib and Antisense MDM2 Cooperatively Inhibit Hormone-Independent Prostate CancerRoberto Bianco, Roberta Caputo, Rosa Caputo, Vincenzo Damiano, Sabino De Placido, Corrado Ficorella, Sudhir Agrawal, A R Bianco, Fortunato Ciardiello, Giampaolo Tortora · 2004 · Clinical Cancer Research
- Geldanamycin Prevents Nuclear Translocation of Mutant p53Gargi Dasgupta, Jamil Antonio Momand · 1997 · Experimental Cell Research
- Exploring the Genetic Orchestra of Cancer: The Interplay Between Oncogenes and Tumor-Suppressor GenesS. P. Singh, Rakesh Bhaskar, Shampa Ghosh, Bhuvaneshwar Yarlagadda, Dr. Krishna Kumar Singh, Prashant Verma, Sonali Sengupta, Mitko I. Mladenov, Nikola Hadzi‐Petrushev, Radoslav Stojchevski et al. · 2025 · Cancers
- Molecular analysis of p53, MDM2 and H-ras genes in low-grade central osteosarcomaHye‐Rim Park, Woon Won Jung, Franco Bertoni, Patrizia Bacchini, Jae Hoon Park, Youn-Wha Kim, Yong-Koo Park · 2004 · Pathology - Research and Practice
- Human Papillomavirus Seropositivity Synergizes withMDM2Variants to Increase the Risk of Oral Squamous Cell CarcinomaXingming Chen, Erich M. Sturgis, Dapeng Lei, Kristina R. Dahlstrom, Qingyi Wei, Guojun Li · 2010 · Cancer Research
- Redirection of T Cells by Delivering a Transgenic Mouse-Derived MDM2 Tumor Antigen-Specific TCR and its Humanized Derviative Is Governed by the CD8 Coreceptor and Affects Natural Human TCR ExpressionRalf-Holger Voss, Jurgen H. E. Kuball, Renate Engel, Philippe Guillaume, Pedro J. Romero, Christoph Huber, Matthias Theobald · 2006 · Immunologic Research
- microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesisCen Zhang, Juan Liu, Chunwen Tan, Xuetian Yue, Yuhan Zhao, Jiaping Peng, Xiaolong Wang, Saurabh V. Laddha, Chang S. Chan, Shu Sen Zheng et al. · 2016 · Oncotarget
- Induction of 18A2/mts1 Gene Expression and Its Effects on Metastasis and Cell Cycle ControlC. Parker, P.A. WHITTAKER, Badar A. Usmani, M.S. Lakshmi, Gajanan V. Sherbet · 1994 · DNA and Cell Biology
- IFN Regulatory Factor 8 Regulates MDM2 in Germinal Center B CellsZhou, Jeff X, Lee, Chang Hoon, Qi, Chen Feng, Wang, Hongsheng, Naghashfar, Zohreh, Abbasi, Sadia, Morse, Herbert C · 2009 · The Journal of Immunology
- MDM2-p53 protein–protein interaction inhibitors: A-ring substituted isoindolinonesAnna F. Watson, Junfeng Liu, Karim Bennaceur, Catherine J. Drummond, Jane Endicott, Bernard T. Golding, Roger J. Griffin, Karen Haggerty, Xiaohong Lü, James M. McDonnell et al. · 2011 · Bioorganic & Medicinal Chemistry Letters
- Mdm2 and the p53 pathway in human pituitary adenomasMohamed Suliman, Janice A. Royds, D. R. Cullen, WALTER R. TIMPERLEY, Tom Powell, Robert D. E. Battersby, T. Hugh Jones · 2001 · Clinical Endocrinology
- Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sitesCristina Bartocci, Eros Lazzerini Denchi · 2013 · Frontiers in Genetics
- CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based TherapiesLong Jiang, Katrine Ingelshed, Yunbing Shen, Sanjaykumar V. Boddul, Vaishnavi Srinivasan Iyer, Zsolt Kasza, Saikiran K. Sedimbi, David Philip Lane, Fredrik Wermeling · 2021 · Cancer Research
- Involvement ofINK4A gene products in the pathogenesis and development of human osteosarcomaM. S. Benassi, Lara Molendini, Gabriella Gamberi, Giovanna Magagnoli, Paola Ragazzini, Giuliana Gobbi, Luca Sangiorgi, Laura Pazzaglia, Julia Asp, Camilla Brantsing et al. · 2001 · Cancer
- Myxoinflammatory fibroblastic sarcoma with complex supernumerary ring chromosomes composed of chromosome 3 segmentsAtiya Mansoor, Nisreen Fidda, Eleanor Himoe, Misty Payne, Helen J. Lawce, R. Ellen Magenis · 2004 · Cancer Genetics and Cytogenetics
- p53 and MDM2 expression in odontogenic cysts and tumoursJúnia Noronha Carvalhais, MCF. Aguiar, Vera Cavalcanti de Araújo, NS de Araújo, Ricardo Santiago Gomez · 1999 · Oral Diseases
- Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGPNadine Van Roy, Anne Forus, Ola Myklebost, Ngan Ching Cheng, Rogier Versteeg, Frank Speleman · 1995 · Cancer Genetics and Cytogenetics
- On the expression of the p53 protein in human cancerDavid Philip Lane · 1994 · Molecular Biology Reports
- NOLC1, an Enhancer of Nasopharyngeal Carcinoma Progression, Is Essential for TP53 to Regulate MDM2 ExpressionYu-Chyi Hwang, Tung‐Ying Lu, Dah‐Yeou Huang, Yuan‐Sung Kuo, Cheng-Fu Kao, Ning-Hsing Yeh, Han‐Chung Wu, Chin‐Tarng Lin · 2009 · American Journal Of Pathology
- Analysis of the molecular species generated by mdm2 gene amplification in liposarcomasElena Tamborini, Gabriella Della Torre, Cinzia Emilia Lavarino, Alberto Azzarelli, Patrizia Carpinelli, Marco Alessandro Pierotti, Silvana Pilotti · 2001 · International Journal of Cancer
- Mdm2 and Tumorigenesis: Evolving Theories and Unsolved MysteriesE. Senturk, James J. Manfredi · 2012 · Genes & Cancer
- A p53 dose-response relationship for sensitivity to DNA damage in isogenic teratocarcinoma cellsStuart G. Lutzker, Robin Mathew, Derek R Taller · 2001 · Oncogene
- NO and transcriptional regulation: from signaling to deathJie Zhou, Bernhard Brüne · 2004 · Toxicology
- On the regulation of the p53 tumour suppressor, and its role in the cellular response to DNA damageDavid Philip Lane, Carol Midgley, Ted R. Hupp, Xin Lü, Bořivoj Vojtěšek, Steven M. Picksley · 1995 · Philosophical Transactions of the Royal Society B Biological Sciences
- Expression of p53, MDM2 protein and Ki-67 antigen in recurrent meningiomasMitsuaki Ohkoudo, Hiroki Sawa, Mitsuhiro Hara, Kazuhiko Saruta, Toshiko Aiso, Reiko Ohki, Hiroshi Yamamoto, Eiji Maemura, Yoshio SHIINA, Masahiko Fujii et al. · 1998 · Journal of Neuro-Oncology
- REVIEW ARTICLE. p53: GUARDIAN OF CELLULAR SENESCENCEDavid Wynford‐Thomas · 1996 · The Journal of Pathology
- Establishment of a cell line with variantBCR/ABL breakpoint expressing P180BCR/ABL from late-appearing Philadelphia-positive acute biphenotypic leukemiaKoiti Inokuchi, Tamiko Shinohara, Makoto Futaki, Hideki Hanawa, Sakae Tanosaki, Hiroki Yamaguchi, Takeo Nomura, Kazuo Dan · 1998 · Genes Chromosomes and Cancer
- Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cellsS Singh, Mahesh Ramamoorthy, Catherine A. Vaughan, William Andrew Yeudall, Sumitra Deb, Sumitra Deb · 2012 · Cell Death and Differentiation
- Gene abnormalities in multiple myeloma; the relevance of TP53, MDM2, and CDKN2A.Manal O. Elnenaei, Alicja Gruszka, Roger A'Hernt, Estella Matutes, Bhawna Sirohi, R Powles, Daniel Catovsky · 2003 · PubMed
- Amplification and Overexpression of mdm2 Gene in EpendymomasSatoshi O. Suzuki, Toru Iwaki · 2000 · Modern Pathology
- Overexpression of MDM2 oncoprotein correlates with possession of estrogen receptor alpha and lack of MDM2 mRNA splice variants in human breast cancerMasao Hori, Jiro Shimazaki, Satoshi Inagawa, Masayuki Itabashi, Mitsuo Hori · 2002 · Breast Cancer Research and Treatment
- (R)-Roscovitine (CYC202, Seliciclib) sensitizes SH-SY5Y neuroblastoma cells to nutlin-3-induced apoptosisJudit Ribas, Jacint Boix, Laurent Meijer · 2006 · Experimental Cell Research
- Amplification of 12q13 and 12q15 Sequences in a Sclerosing Epithelioid FibrosarcomaDavid Gisselsson, Patrik Andreasson, Jeanne M. Meis‐Kindblom, Lars‐Gunnar Kindblom, Fredrik Mertens, Nils Mandahl · 1998 · Cancer Genetics and Cytogenetics
- Immunocytochemical analysis of the tumour suppressor protein (p53) in feline neoplasiaLubna Nasir, Hilary Krasner, David J. Argyle, Alun Williams · 2000 · Cancer Letters
- Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene clusterChengzhen Ren, Cheng Hui Ren, Likun Li, Alexei A. Goltsov, Timothy C. Thompson · 2006 · Genomics
- Function and dysfunction of the human oncoprotein MDM2Swati Palit Deb · 2002 · Frontiers in bioscience
- Worrying about p53David Philip Lane · 1992 · Current Biology
- Abnormal expression of the p53-binding protein MDM2 in Hodgkin's diseaseMarco Chilosi, Claudio Doglioni, Fabio Menestrina, Licia Montagna, Antonella Rigo, Maurizio Lestani, Mattia Barbareschi, Aldo Scarpa, GM Mariuzzi, Giovanni Pizzolo · 1994 · Blood
- p53 Protein Detected By Immunohistochemical Staining is Not Always MutantCatriona MacGeoch, Diana M. Barnes, Julia A. Newton, Shehla N. Mohammed, Shirley Victoria Hodgson, Mun Hon Ng, David Timothy Bishop, Nigel K. Spurr · 1993 · Disease Markers
- Activation of the human immunodeficiency virus type 1 long terminal repeat by transforming mutants of human p53Mark A. Subler, Daniel W. Martin, Sumitra Deb · 1994 · Journal of Virology
- Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.Jeffrey M. Jones, Laura Donatella Attardi, Lucy A. Godley, Rodolfo Laucirica, Daniel Medina, Tyler Jacks, HAROLD E. VARMUS, Lawrence A. Donehower · 1997 · PubMed
- Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylationZheng-Cheng Yu, Yi‐Fu Huang, Sheau-Yann Shieh · 2015 · Nucleic Acids Research
- Overexpression of MDM2 protein in intrahepatic cholangiocarcinoma: relationship with p53 overexpression, Ki-67 labeling, and clinicopathological featuresSatoshi Horie, Kanenori Endo, Hironaka Kawasaki, Tadashi Terada · 2000 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
- Lysine methylation represses p53 activity in teratocarcinoma cancer cellsJiajun Zhu, Zhixun Dou, Morgan A. Sammons, Arnold J. Levine, Shelley L. Berger · 2016 · Proceedings of the National Academy of Sciences
- Molecular biology of gliomasAndrew B. Lassman · 2004 · Current Neurology and Neuroscience Reports
- Malignant fibrous histiocytoma of bone: Analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistryMaija Tarkkanen, Marcelo Luis Larramendy, Tom Böhling, Massimo Serra, Claudia Maria Hattinger, Aarne Kivioja, Inkeri Elomaa, Piero Picci, Sakari Knuutila · 2006 · European Journal of Cancer
- Stabilization and Activation of p53 by the Coactivator Protein TAFII31Thomas Buschmann, Yahong Lin, Nadia Aithmitti, Serge Yu. Fuchs, Hua Lu, Lois Resnick‐Silverman, James J. Manfredi, Ze’ev A. Ronai, Xiangwei Wu · 2001 · Journal of Biological Chemistry
- DisruptingTP53 in mouse models of human cancersJohn M. Parant, Guillermina Lozano · 2003 · Human Mutation
- Amplification and protein expression of chromosome 12q13-15 genes in osteosarcomas of the jawsMárcio Ajudarte Lopes, Nikolaos G. Nikitakis, R.A. Ord, John J. Sauk · 2001 · Oral Oncology
- Multiple Murine Double Minute Gene 2 (MDM2) Proteins Are Induced by Ultraviolet LightLeslie J. Saucedo, Cena D. Myers, Mary Ellen Perry · 1999 · Journal of Biological Chemistry
- Molecular characterization of CD30+ anaplastic large-cell lymphoma: high frequency of c-myc proto-oncogene activationGiorgio Inghirami, L Macri, Ethel Cesarman, Amy Chadburn, J Zhong, DM Knowles · 1994 · Blood
- A Novel Functional Polymorphism C1797G in the MDM2 Promoter Is Associated with Risk of Bladder Cancer in a Chinese PopulationMeilin Wang, Zhizhong Zhang, Haixia Zhu, Guangbo Fu, Shouyu Wang, Dongmei Wu, Jianwei Zhou, Qingyi Wei, Zhengdong Zhang · 2008 · Clinical Cancer Research
- Future of Clinical Genomics in Pediatric OncologyKatherine A. Janeway, Andrew E. Place, Mark W. Kieran, Marian H. Harris · 2013 · Journal of Clinical Oncology
- Prevalence of MDM2 amplification and coalterations in 523 advanced cancer patients in the MD Anderson phase 1 clinicVikas Dembla, Neeta Somaiah, Pedro Coelho Barata, Kenneth R. Hess, Siqing Fu, Filip Jankú, Daniel D. Karp, Aung Naing, Sarina Anne Piha-Paul, Vivek Subbiah et al. · 2018 · Oncotarget
- Role of MDM2 Overexpression in Doxorubicin Resistance of Breast CarcinomaAkio Suzuki, Masakazu Toi, Yutaka Yamamoto, Shigehira Saji, Mariko Muta, Takeshi Tominaga · 1998 · Japanese Journal of Cancer Research
- p53 protein expression in nephroblastomas: a predictor of poor prognosisDhirendra Govender, P Harilal, G. P. Hadley, Runjan Chetty · 1998 · British Journal of Cancer
- Cellular adhesion regulates p53 protein levels in primary human keratinocytes.Janice M. Nigro, Kenneth Aldape, Suzanne M. Hess, Thea Dorothy Tlsty · 1997 · PubMed
- Posttransplant skin cancer: A possible role for p53 gene mutation but not for oncogenic human papillomavirusesJane McGregor, Alan Farthing, Tim Crook, Carmen C. -W. Yu, Edwin A. Dublin, David A. Levison, D.M. MACDONALD · 1994 · Journal of the American Academy of Dermatology
- t(12;22)(q13;q13) and trisomy 8 are nonrandom aberrations in clear-cell sarcomaEduardo Rodrı́guez, Chandrika Sreekantaiah, Victor E. Reuter, Robert John Motzer, Raju S. K. Chaganti · 1992 · Cancer Genetics and Cytogenetics
- Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridizationAgnès Marchio, Mounira Meddeb, Pascal Pineau, Gisèle Danglot, Pierre Tiollais, Alain Bernheim, Anne Dejean · 1997 · Genes Chromosomes and Cancer
- Transfection of wild-type but not mutant p53 induces early monocytic differentiation in HL60 cells and increases their sensitivity to stress.Debashmita Banerjee, H.J. Lenz, Barbara Schnieders, D J Manno, Jingfang Ju, Colin Paul Spears, Daniel Hochhauser, Kathleen D. Danenberg, P. V. Danenberg, J R Bertino · 1995 · PubMed
- Discovery of DS-5272 as a promising candidate: A potent and orally active p53–MDM2 interaction inhibitorMasaki Miyazaki, Kouichi Uoto, Yuuichi Sugimoto, Hiroyuki Naito, Keisuke Yoshida, Tooru Okayama, Haruko C. Kawato, Masaya Miyazaki, Mayumi Kitagawa, Takahiko Seki et al. · 2015 · Bioorganic & Medicinal Chemistry
- Correlation of TP53 and MDM2 genotypes with response to therapy in sarcomaHege Oma Ohnstad, Russell Castro, Jinchang Sun, Karen‐Marie Heintz, Lyubomir T. Vassilev, Bodil Bjerkehagen, Stine H. Kresse, Leonardo A. Meza‐Zepeda, Ola Myklebost · 2012 · Cancer
- Improvement of the synthesis and pharmacokinetic properties of chromenotriazolopyrimidine MDM2-p53 protein-protein inhibitorsHilary P. Beck, Michael R. DeGraffenreid, Brian M. Fox, John G. Allen, Yosup Rew, Stephen Schneider, Anne Y. Saiki, Dongyin Yu, Jonathan D. Oliner, Kevin L. Salyers et al. · 2010 · Bioorganic & Medicinal Chemistry Letters
- Design, Synthesis, Chemical and Biochemical Insights Into Novel Hybrid Spirooxindole-Based p53-MDM2 Inhibitors With Potential Bcl2 Signaling AttenuationYasmine M. Abdel Aziz, Gehad Lotfy, Mohamed M. Said, El Sayed H. El Ashry, El Sayed H. El Tamany, Saied M. Soliman, Marwa Muhammad Abu-Serie, Mohamed Teleb, Sammer Yousuf B, Alexander S. S. Dömling et al. · 2021 · Frontiers in Chemistry
- Localization of the Human Stat6 Gene to Chromosome 12q13.3–q14.1, a Region Implicated in Multiple Solid TumorsBharvin K.R. Patel, Catherine L. Keck, Ryan S. O'Leary, Nicholas C. Popescu, William J. LaRochelle · 1998 · Genomics
- Suppression of hypoxia inducible factor-1α (HIF-1α) by YC-1 is dependent on murine double minute 2 (Mdm2)Chi Keung Lau, Zhen Fan Yang, Chi Tat Lam, Ka Ho Tam, Ronnie T. P. Poon, Sheung Tat Fan · 2006 · Biochemical and Biophysical Research Communications
- TP53 Mutations in Canine Brain TumorsDaniel S. York, R. J. Higgins, Richard A. LeCouteur, ALLAN WOLFE, Robert A. Grahn, Natasha J. Olby, M. Campbell, Peter J. Dickinson · 2011 · Veterinary Pathology
- p53 alterations in recurrent squamous cell cancer of the head and neck refractory to radiotherapyIan Ganly, David S. Soutar, Robert Eldon Brown, Stuart B. Kaye · 2000 · British Journal of Cancer
- Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriersE. Copson, H. White, J. Blaydes, D. Robinson, Peter W. M. Johnson, D. Eccles · 2006 · BMC Cancer
- MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8+ autologous T lymphocytesChristine Mayr, Dagmar Bund, Martin Schlee, Martina Bamberger, David M. Kofler, Michael J. Hallek, Clemens‐Martin Wendtner · 2006 · Experimental Hematology
- Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrationsΒ. Michael Ghadimi, Dan L. Sackett, Michael J. Difilippantonio, Evelin Schr�ck, Thomas Neumann, Annukka Jauho, Gert Auer, Thomas Ried · 2000 · Genes Chromosomes and Cancer
- Low grade fibromyxoid sarcomaAlessandra Mezzelani, Gabriella Sozzi, Michelle Neßling, Carla Riva, Gabriella Della Torre, M. Testi, Alberto Azzarelli, Marco Alessandro Pierotti, Peter Lichter, Silvana Pilotti · 2000 · Cancer Genetics and Cytogenetics
- Phosphorylation Studies on Rat p53 Using the Baculovirus Expression SystemBergund Fuchs, Doris Hecker, Karl Heinz Scheidtmann · 1995 · European Journal of Biochemistry
- Analysis of the p16INK4 and TP53 tumor suppressor genes in bone sarcoma pediatric patientsAna Patiño‐García, Luis Sierrasesúmaga · 1997 · Cancer Genetics and Cytogenetics
- The Tumor Suppressor ING1: Structure and FunctionK.-John Cheung, Gang Li · 2001 · Experimental Cell Research