Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gpl60
Hallenberger, Sabine, Bosch, Valerie, Angliker, Herbert, Shaw, Elliott, Klenk, Hans-Dieter, Garten, Wolfgang·1992·Nature
DOI 10.1038/360358a0
Cited by (586)
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- Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered α2-macroglobulin containing a furin recognition sequence in the bait regionLuc Van Rompaey, Torik Ayoubi, Wim Van de Ven, Peter Marynen · 1997 · Biochemical Journal
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- Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA AssayMaxime Veillette, Mathieu Coutu, Jonathan Richard, Laurie-Anne Batraville, Anik Désormeaux, Michel Roger, Andrés Finzi · 2014 · Journal of Visualized Experiments
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- Processing and major histocompatibility complex binding of the MTV7 superantigenGary M. Winslow, Philippa Marrack, John W. Kappler · 1994 · Immunity
- Characterization of Proprotein Convertases and Their Involvement in Virus PropagationWolfgang Garten · 2018 · Springer eBooks
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- Furin is important but not essential for the proteolytic maturation of gp160 of HIV‐1Mili Gu, Jay Rappapor, Stephen Howard Leppla · 1995 · FEBS Letters
- Endoprotease Activities Other Than Furin and PACE4 with a Role in Processing of HIV-I gp160 Glycoproteins in CHO-K1 CellsNoel M. Inocencio, Joseph F. Sucic, Joan M. Moehring, Michael J. Spence, Thomas J. Moehring · 1997 · Journal of Biological Chemistry
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- Analysis of mutations in alleles of thefur gene from an endoprotease-deficient chinese hamster ovary cell strainMichael J. Spence, Joseph F. Sucic, Brian Thomas Foley, Thomas J. Moehring · 1995 · Somatic Cell and Molecular Genetics
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- Serpin‐like properties of α1‐antitrypsin Portland towards furin convertaseErick K. Dufour, Jean‐Bernard Denault, Paul C.R. Hopkins, Richard Leduc · 1998 · FEBS Letters
- Role of gp41 Glycosylation Sites in the Biological Activity of Human Immunodeficiency Virus Type 1 Envelope GlycoproteinClaire Perrin, Emmanuel Fenouillet, Ian Martin Jones · 1998 · Virology
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- Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cellsYinghui Lu, Kornelia Hardes, Sven O. Dahms, Eva Böttcher‐Friebertshäuser, Torsten Steinmetzer, Manuel E. Than, Hans‐Dieter Klenk, Wolfgang Garten · 2015 · Antiviral Research
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- Generation and characterization of non-competitive furin-inhibiting nanobodiesJingjing Zhu, Jeroen Declercq, Bart Roucourt, Gholamreza Hassanzadeh Ghassabeh, Sandra M.P. Meulemans, Jörg Kinne, Guido David, Alphons J.M. Vermorken, Wim J.M. Van de Ven, Iris Lindberg et al. · 2012 · Biochemical Journal
- The Enzymology of PC1 and PC2A. Cameron, Ekaterina V. Apletalina, Iris Lindberg · 2002 · The Enzymes
- Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in miceTie‐Gang Meng, Mengwen Hu, Xue‐Shan Ma, Lin Huang, Qiuxia Liang, Yue Yuan, Yi Hou, Hongmei Wang, Heide Schatten, Zhen‐Bo Wang et al. · 2017 · Cell Death and Disease
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- Design and synthesis of novel inhibitors of prohormone convertasesAjoy Basak, François Jean, Nabil Georges Seidah, Claude Lazure · 1994 · International journal of peptide & protein research
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- Domain Flexibility Modulates the Heterogeneous Assembly Mechanism of Anthrax Toxin Protective AntigenGeoffrey K. Feld, Alexander F. Kintzer, Iok I. Tang, Katie L. Thoren, Bryan A. Krantz · 2011 · Journal of Molecular Biology
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- Immunohistochemical localization of subtilisin/kexin-like proprotein convertases in human atherosclerosisPhilipp Stawowy, Heike Kallisch, Núbia Borges Pereira Stawowy, Dietger Stibenz, John P. Veinot, Michael Gräfe, Nabil Georges Seidah, Michel Chrétien, Eckart Fleck, Kristof Graf · 2005 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
- Biochemical and Genetic Definition of the Cellular Protease Required for HIV-1 gp160 ProcessingAlex Franzusoff, Alison M. Volpe, Denise Josse, Sergio E. Pichuantes, Joseph R. Wolf · 1995 · Journal of Biological Chemistry
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- Endoproteolytic cleavage of HIV-1 gp160 envelope precursor occurs after exit from the trans-Golgi network (TGN)M.-L. Kantanen, Pauli Leinikki, Esa Kuismanen · 1995 · Archives of Virology
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- The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1Kevin C. Olivieri, Robert M. Scoggins, Yeou-Cherng Bor, Aprille L. Matthews, David Mark, James R. Taylor, D Chernauskas, Marie‐Louise Hammarskjöld, David M. Rekosh, David Camerini · 2006 · Virology
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- Role of Human Immunodeficiency Virus Type 1 Envelope Structure in the Induction of Broadly Neutralizing AntibodiesFahd Benjelloun, Philip Lawrence, Bernard Verrier, Christian Genin, Stéphane Paul · 2012 · Journal of Virology
- HIV-1 proprotein processing as a target for gene therapyPierre Cordelier, Mark Α. Zern, D S Strayer · 2003 · Gene Therapy
- Proteolytic processing is required for viral superantigen activity.Chae Gyu Park, M Y Jung, Yongwon Choi, Gary M. Winslow · 1995 · The Journal of Experimental Medicine
- HIV-1 gp120 dimers decrease the overall affinity of gp120 preparations for CD4-induced ligandsMathieu Coutu, Andrés Finzi · 2015 · Journal of Virological Methods
- Retroviral Env Glycoprotein Trafficking and Incorporation into VirionsTsutomu Murakami · 2012 · Molecular Biology International
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- Cellular Entry of RetrovirusesDirk Lindemann, Imke Steffen, Stefan Pöhlmann · 2013 · Advances in experimental medicine and biology
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- Carboxy-Terminal Proteolytic Processing at a Consensus Furin Cleavage Site Is a Prerequisite Event for Quail ZPC Secretion1Tomohiro Sasanami, Masaru Toriyama, Makoto Mori · 2003 · Biology of Reproduction
- Design, Expression, and Immunogenicity of a Soluble HIV Trimeric Envelope Fragment Adopting a Prefusion gp41 ConfigurationZhi‐Song Qiao, Mikyung Kim, Bruce B. Reinhold, David C. Montefiori, Jia‐Huai Wang, Ellis L. Reinherz · 2005 · Journal of Biological Chemistry
- Furin-mediated proprotein processing activity: Involvement of negatively charged amino acid residues in the substrate binding regionAnton Roebroek, John W.M. Creemers, Torik Ayoubi, Wim J.M. Van de Ven · 1994 · Biochimie
- Three-Dimensional Structure of Chymotrypsin Inactivated with (2S)-N-Acetyl-L-alanyl-L-phenylalanyl .alpha.-chloroethane: Implications for the Mechanism of Inactivation of Serine Proteases by ChloroketonesKevin D. Kreutter, Anke C. U. Steinmetz, Tzyy Chyau Liang, Maryfrances Prorok, Robert H. Abeles, Dagmar Ringe · 1994 · Biochemistry
- Transfer of endoplasmic reticulum and Golgi retention signals to human immunodeficiency virus type 1 gp160 inhibits intracellular transport and proteolytic processing of viral glycoprotein but does not influence the cellular site of virus particle budding.Tanya Pfeiffer, H. Zentgraf, Bettina Freyaldenhoven, V. Bosch · 1997 · Journal of General Virology
- Synthesis and Characterization of Heteroarotinoids Demonstrate Structure Specificity RelationshipsDoris M. Benbrook, Shankar Subramanian, Jonathan B. Gale, Shengquan Liu, Chad W. Brown, Marcus F. Boehm, Kenneth Darrell Berlin · 1998 · Journal of Medicinal Chemistry
- Viral envelope glycoprotein processing by proprotein convertasesAntonella Pasquato, Joel Ramos da Palma, Clara Galan-Navarro, Nabil Georges Seidah, Stefan Kunz · 2013 · Antiviral Research
- Circulating furin, IL-6, and presepsin levels and disease severity in SARS-CoV-2–infected patientsAbdürrahim Koçyiğit, Özgür Söğüt, Ezgi Durmuş, Ebru Kanımdan, Eray Metin Güler, Onur Kaplan, Vildan Betül Yenigun, Canan Eren, Zeynep Özman, Oznur Yasar · 2021 · Science Progress
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- Mutations in Envelope gp120 Can Impact Proteolytic Processing of the gp160 Precursor and Thereby Affect Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 PseudovirusesW. Blay, Theresa Kasprzyk, L. Misher, B. Richardson, N. Haigwood · 2007 · Journal of Virology