Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gpl60

Hallenberger, Sabine, Bosch, Valerie, Angliker, Herbert, Shaw, Elliott, Klenk, Hans-Dieter, Garten, Wolfgang·1992·Nature

Cited by (586)

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  2. Virus-like particle and DNA-based candidate AIDS vaccines
    Qizhi Cathy Yao · 2003 · Vaccine
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  7. Molecular mechanisms of interspecies transmission and pathogenicity of influenza viruses: Lessons from the 2009 pandemic
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  19. How Do Enveloped Viruses Exploit the Secretory Proprotein Convertases to Regulate Infectivity and Spread?
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  20. Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered α2-macroglobulin containing a furin recognition sequence in the bait region
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    Dominik Hotter, Daniel Sauter, Frank Kirchhoff · 2016 · Small GTPases
  22. Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
    Maxime Veillette, Mathieu Coutu, Jonathan Richard, Laurie-Anne Batraville, Anik Désormeaux, Michel Roger, Andrés Finzi · 2014 · Journal of Visualized Experiments
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    Arne Fischoeder, Heike Meýborg, Dietger Stibenz, Eckart Fleck, Kristof Graf, Philipp Stawowy · 2006 · Cardiovascular Research
  24. Polyarginine Inhibits gp160 Processing by Furin and Suppresses Productive Human Immunodeficiency Virus Type 1 Infection
    Karen V. Kibler, Akiko Miyazato, Venkat S. R. K. Yedavalli, Andrew I. Dayton, Bertram L. Jacobs, George Dapolito, Seong‐Jin Kim, Kuan‐Teh Jeang · 2004 · Journal of Biological Chemistry
  25. Processing and major histocompatibility complex binding of the MTV7 superantigen
    Gary M. Winslow, Philippa Marrack, John W. Kappler · 1994 · Immunity
  26. Characterization of Proprotein Convertases and Their Involvement in Virus Propagation
    Wolfgang Garten · 2018 · Springer eBooks
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    Geetanjali Negi, Anurag Sharma, Manorama Dey, Garvita Dhanawat, Nagma Parveen · 2022 · Biophysical Reviews
  28. Cleavage at the Furin Consensus Sequence RAR/KR 109 and Presence of the Intervening Peptide of the Respiratory Syncytial Virus Fusion Protein Are Dispensable for Virus Replication in Cell Culture
    Gert Zimmer, Karl‐Klaus Conzelmann, Georg Herrler · 2002 · Journal of Virology
  29. Host virus interactions and the molecular regulation of HIV-1: Role in the pathogenesis of HIV-associated nephropathy
    Jay Rappaport, Jeffrey B. Kopp, Paul E. Klotman · 1994 · Kidney International
  30. Furin is important but not essential for the proteolytic maturation of gp160 of HIV‐1
    Mili Gu, Jay Rappapor, Stephen Howard Leppla · 1995 · FEBS Letters
  31. Endoprotease Activities Other Than Furin and PACE4 with a Role in Processing of HIV-I gp160 Glycoproteins in CHO-K1 Cells
    Noel M. Inocencio, Joseph F. Sucic, Joan M. Moehring, Michael J. Spence, Thomas J. Moehring · 1997 · Journal of Biological Chemistry
  32. DDX17 promotes the production of infectious HIV-1 particles through modulating viral RNA packaging and translation frameshift
    René-Pierre Lorgeoux, Qinghua Pan, Yann Le Duff, Liang Chen · 2013 · Virology
  33. Emerging Infections: A Tribute to the One Medicine, One Health Concept
    R. E. Kahn, Deborah F. Clouser, Jüergen A. Richt · 2009 · Zoonoses and Public Health
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    Michel Chrétien, Nabil Georges Seidah, Ajoy Basak, Majambu Mbikay · 2008 · Expert Opinion on Therapeutic Targets
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  44. Analysis of mutations in alleles of thefur gene from an endoprotease-deficient chinese hamster ovary cell strain
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  51. Serpin‐like properties of α1‐antitrypsin Portland towards furin convertase
    Erick K. Dufour, Jean‐Bernard Denault, Paul C.R. Hopkins, Richard Leduc · 1998 · FEBS Letters
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  71. Biochemical and Genetic Definition of the Cellular Protease Required for HIV-1 gp160 Processing
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  73. Endoproteolytic cleavage of HIV-1 gp160 envelope precursor occurs after exit from the trans-Golgi network (TGN)
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  78. The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1
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  83. HIV-1 proprotein processing as a target for gene therapy
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  84. Proteolytic processing is required for viral superantigen activity.
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  85. HIV-1 gp120 dimers decrease the overall affinity of gp120 preparations for CD4-induced ligands
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  86. Retroviral Env Glycoprotein Trafficking and Incorporation into Virions
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  92. Furin-mediated proprotein processing activity: Involvement of negatively charged amino acid residues in the substrate binding region
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