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Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A

Daaka, Yehia, Luttrell, Louis M., Lefkowitz, Robert J.·1997·Nature
DOI 10.1038/36362
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Research works printed but not linked: 28

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  2. Xiao, R., Ji, X. & Lakatta, E. G. Functional coupling of the β2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes. Mol. Pharmacol. 47, 322–329 (1995).
  3. Laugwitz, K.-L. et al. The human thyrotropin receptor: A heptahelical receptor capable of stimulating members of all four G protein families. Proc. Natl Acad. Sci. USA 93, 116–120 (1996). · DOI · Paper page
  4. Herrlich, A. et al. Involvement of Gsand Giproteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C. J. Biol. Chem. 271, 16764–16772 (1996). · doi:10.1074/jbc.271.28.16764
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  10. Luttrell, L. M. et al. Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gβγ subunit-mediated activation of mitogen-activated protein kinases. J. Biol. Chem. 271, 19443–19450 (1996). · DOI · Paper page
  11. Luttrell, L. M., Della Rocca, G. J., van Biesen, T., Luttrell, D. K. & Lefkowitz, R. J. Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor: A scaffold for G protein-coupled receptor-mediated Ras activation. J. Biol. Chem. 272, 4637–4644 (1997). · DOI · Paper page
  12. Chen, Y., Pouysségur, J., Courtneidge, S. A. & van Obberghen-Schilling, E. Activation of Src family kinase activity by G protein-coupled thrombin receptor in growth-responsive fibroblasts. J. Biol. Chem. 269, 27372–27377 (1994). · DOI · Paper page
  13. Boguski, M. S. & McCormick, F. Proteins regulating Ras and its relatives. Nature 336, 643–653 (1993). · DOI · Paper page
  14. Hordijk, P. L., Verlaan, I., van Corven, E. J. & Moolenaar, W. H. Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts: Evidence that phosphorylation of MAP kinase is mediated by the Gi-p21ras pathway. J. Biol. Chem. 269, 645–651 (1994). · DOI
  15. van Biesen, T. et al. Receptor-tyrosine kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway. Nature 376, 781–784 (1995). · DOI · Paper page
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  18. Okamoto, T. et al. Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation. Cell 67, 723–730 (1991). · DOI · Paper page
  19. Chambard, J. C., Paris, L., L'Allemain, G. & Pouysségur, J. Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin. Nature 326, 800–803 (1987). · DOI
  20. van Corven, E. J., Groenink, A., Jalik, K., Eichholtz, T. & Moolenaar, W. H. Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins. Cell 59, 45–54 (1989). · DOI · Paper page
  21. Cowley, S., Paterson, H., Kemp, P. & Marshall, C. J. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and transformation of NIH3T3 cells. Cell 77, 841–852 (1994). · DOI · Paper page
  22. Yarwood, S. J., Kilgour, E. & Anderson, N. G. Cyclic AMP stimulates the phosphorylation and activation of p42 and p44 mitogen-activated protein kinases in 3T3-F442A preadipocytes. Biochem. Biophys. Res. Comm. 224, 734–739 (1996). · doi:10.1006/bbrc.1996.1092
  23. McKenzie, F. R. & Pouysségur, J. cAMP-mediated growth inhibition in fibroblasts is not mediated via mitogen-activated protein (MAP) kinase (Erk) inhibition: cAMP-dependent protein kinase induces a temporal shift in growth factor-stimualted MAP kinases. J. Biol. Chem. 271, 13476–13483 (1996). · DOI
  24. Cook, S. J. & McCormick, F. Inhibition by cAMP of Ras-dependent activation of Raf. Science 262, 1069–1072 (1993). · DOI · Paper page
  25. Hordijk, P. L., Verlaan, I., Jalnik, K., van Corven, E. J. & Moolenaar, W. H. cAMP abrogates the p21ras -mitogen-activated protein kinase pathway in fibroblasts. J. Biol. Chem. 269, 3534–3538 (1994). · DOI · Paper page
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  27. Daaka, Y. et al. Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases. Proc. Natl Acad. Sci. USA 94, 2180–2185 (1997). · doi:10.1073/pnas.94.6.2180
  28. Krueger, K. M., Daaka, Y., Pitcher, J. A. & Lefkowitz, R. J. The role of sequestration in G protein-coupled receptor resensitization: Regulation of β2-adrenergic receptor dephosphorylation by vesicular acidification. J. Biol. Chem. 272, 5–8 (1997). · DOI · Paper page

Cited by

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Metadata

Authors
Daaka, Y., Luttrell, L. M., & Lefkowitz, R. J.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
1997-11
Volume
390
Issue
6655
Pages
88-91
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
DOI
10.1038/36362
OpenAlex
W1769585641
Cited by
1,270
References
0
FWCI
19.69
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (unspecified)

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Daaka, Y., Luttrell, L. M., & Lefkowitz, R. J. (1997). Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A. Nature. https://doi.org/10.1038/36362

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