The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

Ye, Yihong, Meyer, Hemmo H., Rapoport, Tom A.·2001·Nature

DOI 10.1038/414652a

Cited by (1,000)

Items 801–900 of 1,000

Negative feedback and modern anti‐cancer strategies targeting the ER stress response
Yaofu Liu, Zhenzhi Tan, Yili Yang · 2020 · FEBS Letters
A channel for protein waste
Randy W. Schekman · 2004 · Nature
Ricin B Chain Targeted to the Endoplasmic Reticulum of Tobacco Protoplasts Is Degraded by a CDC48- and Vacuole-independent Mechanism*
Kerry L. Chamberlain, Richard Scott Marshall, Nicholas A. Jolliffe, Lorenzo Frigerio, Aldo Ceriotti, Janet M. Lord, Lynne M. Roberts · 2008 · Journal of Biological Chemistry
Pathomechanisms of Inherited Retinal Degeneration and Perspectives for Neuroprotection
Arianna Tolone, Merve Sen, Yiyi Chen, Marius Ueffing, Blanca Arango‐González, François Paquet‐Durand · 2022 · Cold Spring Harbor Perspectives in Medicine
CRISPR-Cas-mediated unfolded protein response control for enhancing plant stress resistance
Bich Ngoc Vu, Tien Van Vu, Jae Yong Yoo, Ngan Thi Nguyen, Ki Seong Ko, Jae‐Yean Kim, Kyun Oh Lee · 2023 · Frontiers in Plant Science
Forced interaction of cell surface proteins with Derlin-1 in the endoplasmic reticulum is sufficient to induce their dislocation into the cytosol for degradation
Sunglim Cho, Miriam Lee, Youngsoo Jun · 2012 · Biochemical and Biophysical Research Communications
Human ASPL/TUG interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the ER-associated degradation defect
Louise Madsen, Karen Molbæk, Ida B Larsen, Sofie Vincents Nielsen, Esben G. Poulsen, Peter S. Walmod, Kay Hofmann, Michael Seeger, Chen-Ying Chien, Rey‐Huei Chen et al. · 2014 · BMC Cell Biology
Upregulation of NPL4 promotes bladder cancer cell proliferation by inhibiting DXO destabilization of cyclin D1 mRNA
Bao‐Sai Lu, Yue-Wei Yin, Yanping Zhang, Ping‐Ying Guo, Wei Li, Kai-Long Liu · 2019 · Cancer Cell International
Derlin-1 and TER94/VCP/p97 are required for intestinal homeostasis
Fuli Liu, Hang Zhao, Ruiyan Kong, Lin Shi, Zhengran Li, Rui Ma, Huiqing Zhao, Zhouhua Li · 2021 · Journal of genetics and genomics/Journal of Genetics and Genomics
Targeted degradation of ABC transporters in health and disease
Daphne Nikles, Robert Tampé · 2007 · Journal of Bioenergetics and Biomembranes
The C-Terminal Amino Acid of the MHC-I Heavy Chain Is Critical for Binding to Derlin-1 in Human Cytomegalovirus US11-Induced MHC-I Degradation
Sunglim Cho, Bo Young Kim, Kwangseog Ahn, Youngsoo Jun · 2013 · PLoS ONE
ER-stress-inducible Herp, facilitates the degradation of immature nicastrin
Toshihiro Marutani, Tomoji Maeda, Chiaki Tanabe, Kun Zou, Wataru Araki, Koichi Kokame, Makoto Michikawa, Hiroto Komano · 2011 · Biochimica et Biophysica Acta (BBA) - General Subjects
Valosin‐containing protein/p97 interacts with sperm‐activating and sperm‐attracting factor (SAAF) in the ascidian egg and modulates sperm‐attracting activity
Eri Kondoh, Aru Konno, Kazuo Inaba, Tohru Oishi, Michio Murata, Manabu Yoshida · 2008 · Development Growth & Differentiation
Atypical ubiquitination of proteins
О.А. Бунеева, A. E. Medvedev · 2016 · Biomeditsinskaya Khimiya
VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation
Philip L. Bailin, Yu Cui, Jun Wei, Chao Liu, Yuhan Chen, Chun‐Ping Cui, Lei Li, Xueli Zhang, Lingqiang Zhang · 2018 · The FASEB Journal
Distinguishing between retention signals and degrons acting in ERAD
Ilana Shapira, Dana Charuvi, Yechiel Elkabetz, Koret Hirschberg, Shoshana Bar‐Nun · 2007 · Journal of Cell Science
Emerging Mechanistic Insights into AAA Complexes Regulating Proteasomal Degradation
Friedrich G. Förster, Jan M. Schuller, Pia Unverdorben, Antje Aufderheide · 2014 · Biomolecules
New Regulators of Clathrin-Mediated Endocytosis Identified in Saccharomyces cerevisiae by Systematic Quantitative Fluorescence Microscopy
Kristen B. Farrell, Caitlin Grossman, Santiago M. Di Pietro · 2015 · Genetics
Endoplasmic Reticulum-associated Protein Degradation in Plant Cells
Aldo Ceriotti, Lynne M. Roberts · 2006 · Plant cell monographs
Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules
Daniel C. Chapman, Paweł Stocki, David B. Williams · 2015 · PLoS ONE
Folding and Quality Control of Glycoproteins
Tadashi Suzuki, K. Tanabe, Y. Funakoshi · 2007 · Elsevier eBooks
Methodologies to monitor protein turnover at the inner nuclear membrane
Pei-Ling Tsai, Chenguang Zhao, Christian D. Schlieker · 2019 · Methods in enzymology on CD-ROM/Methods in enzymology
A small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis
Wenjing Yan, Daniel C. Talley, Antara Syam, Carina Danchik, Yongwang Zhong, Xianzheng Zhang, Xiaoying Liu, Bolormaa Baljinnyam, Stephen C. Kales, Matthew G. Cyr et al. · 2026 · Nature Communications
p97/VCP Promotes the Recycling of Endocytic Cargo
Mona Kawan, Maria Körner, Andreas Schlösser, Alexander Buchberger · 2023 · Molecular Biology of the Cell
Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules
Ines Forrest, Louis Patrick Conway, Clara Gathmann, Appaso Mahadev Jadhav, Tzu-Yuan Chiu, Christian M. Chaheine, Michelle A. Estrada, Anurupa Shrestha, Kathy Sarris, Justin M. Reitsma et al. · 2025 · ACS Central Science
Viruses Hijack ERAD to Regulate Their Replication and Propagation
Linke Zou, Xinyan Wang, Feifan Zhao, Keke Wu, Xiaowen Li, Zhaoyao Li, Yuwan Li, Wenxian Chen, Sen Zeng, Xiaodi Liu et al. · 2022 · International Journal of Molecular Sciences
Yeast derlin Dfm1 employs a chaperone-like function to resolve misfolded membrane protein stress
Rachel Kandel, Jasmine Jung, Della Syau, Tiffany Kuo, Livia D. Songster, Casey Horn, Claire Chapman, Analine Aguayo, Sascha H. C. Duttke, Christopher W. Benner et al. · 2023 · PLoS Biology
A ubiquitin–proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis
Toan Khanh Le, Yasuhiro Hirano, Haruhiko Asakawa, Koji Okamoto, Tatsuo Fukagawa, Tokuko Haraguchi, Yasushi Hiraoka · 2023 · Journal of Cell Science
An autosomal-dominant childhood-onset disorder associated with pathogenic variants in VCP
Annelise Y. Mah-Som, Jil Daw, Diana Huynh, Mengcheng Wu, Benjamin C. Creekmore, William Burns, Steven A. Skinner, Øystein L. Holla, Marie Falkenberg Smeland, Marc Planes et al. · 2023 · The American Journal of Human Genetics
MHC Class I Antigen Presentation of DRiP-Derived Peptides from a Model Antigen Is Not Dependent on the AAA ATPase p97
Amy L. Palmer, Brian P. Dolan · 2013 · PLoS ONE
Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane
Nathan Smith, David J. Adle, Miaoyun Zhao, Xiaojuan Qin, Heejeong Kim, Jaekwon Lee · 2016 · Journal of Biological Chemistry
Thrombospondin-1 counteracts the p97 inhibitor CB-5083 in colon carcinoma cells
Nam-Gu Her, Santosh Kesari, Elmar Nurmemmedov · 2020 · Cell Cycle
Roles of Ubiquitin in Endoplasmic Reticulum-Associated Protein Degradation (ERAD)
Veit Goder · 2012 · Current Protein and Peptide Science
Small Molecule Targets Env for Endoplasmic Reticulum-Associated Protein Degradation and Inhibits Human Immunodeficiency Virus Type 1 Propagation
Alenka Jejcic, Robert Daniels, Laura Goobar-Larsson, Daniel N. Hebert, Anders G. Vahlne · 2009 · Journal of Virology
Mouse Mammary Tumor Virus Signal Peptide Uses a Novel p97-Dependent and Derlin-Independent Retrotranslocation Mechanism To Escape Proteasomal Degradation
Hyewon Byun, P.K. Das, Houqing Yu, Alejandro Alemán, Mary M. Lozano, Andreas T. Matouschek, Jaquelin P. Dudley · 2017 · mBio
Disruption of p97/VCP induces autophagosome accumulation, cell cycle arrest and apoptosis in human choriocarcinoma cells
Raziye Desdicioğlu, Cansu Sahin, Ayşe Filiz YAVUZ, Sevil Çaylı · 2021 · Molecular Biology Reports
Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1
Thang Quyet Nguyen, Le Thi My Le, Do Hyeon Kim, Kyung Soo Ko, Hee Taek Lee, Yen Thi Kim Nguyen, Hyoun Sook Kim, Byung Woo Han, Wonchull Kang, Jin Kuk Yang · 2022 · Structure
The role of RNF149 in the pre-emptive quality control substrate ubiquitination
Aster Legesse, Nathali Kaushansky, Ilana Braunstein, Haddas Saad, Gerardo Zelmar Lederkremer, Ami Navon, Ariel Stanhill · 2023 · Communications Biology
Electronic behaviors of calcined materials obtained from samarium-O-aryl moiety hybrid copolymers
Hiroshi Matsui, T. Kawahara, R. Kudo, M. Uda, S. Karuppuchamy, Masakuni Yoshihara · 2007 · Journal of Alloys and Compounds
Cdc48 Chaperone and Adaptor Ubx4 Distribute the Proteasome in the Nucleus for Anaphase Proteolysis
Chen-Ying Chien, Rey‐Huei Chen · 2013 · Journal of Biological Chemistry
Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation
Joel H. Otero, Jinfeng Suo, Colin Gordon, Eric C. Chang · 2010 · Cell Cycle
Characterization of the Drosophila Atlastin Interactome Reveals VCP as a Functionally Related Interactor
Niamh C. O’Sullivan, Nina M. Dräger, Cahir J. O’Kane · 2013 · Journal of genetics and genomics/Journal of Genetics and Genomics
The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Proteostasis Factors
Benjamin C. Creekmore, Yi‐Wei Chang, Edward B. Lee · 2021 · Journal of Neuropathology & Experimental Neurology
Complement yourself: transcomplementation rescues partially folded mutant proteins
Liudmila Cebotaru, William B. Guggino · 2014 · Biophysical Reviews
AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts
Masaru Kato, Caroline Ospelt, Christoph Kolling, Tomohiro Shimizu, Michihito Kono, Shinsuke Yasuda, Beat A. Michel, Renate E. Gay, Steffen Gay, Kerstin Klein et al. · 2016 · Oncotarget
An engineered, quantifiable in vitro model for analysing the effect of proteostasis-targeting drugs on tissue physical properties
Sandra Loaiza, Sílvia A. Ferreira, Tamara M. Chinn, Alexander C. Kirby, Elena Tsolaki, Camilla Dondi, Katarzyna Parzych, Adam Patrick Strange, Laurent Bozec, Sérgio Bertazzo et al. · 2018 · Biomaterials
VCP myopathy: A family with unusual clinical manifestations
Xuan Guo, Zhe Zhao, Hongrui Shen, Bing Qi, Nan Li, Jing Hu · 2018 · Muscle & Nerve
N-Linked Carbohydrates Act as Lumenal Maturation and Quality Control Protein Tags
Robert Daniels, Sherri Svedine, Daniel N. Hebert · 2004 · Cell Biochemistry and Biophysics
The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP
Maria Körner, Susanne Meyer, G. Marincola, Maximilian J Kern, Clemens Grimm, Christina Schuelein-Voelk, Utz Fischer, Kay Hofmann, Alexander Buchberger · 2023 · eLife
Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response
Yaofu Liu, Yuexi Gu, Ying Chen, Xuan Wang, Guangfeng Zhou, Jing Li, Haoxin Zhao, Mu Wang, Yili Yang, Yili Yang · 2024 · Cell Reports
Exercise mitigates reductive stress-induced cardiac remodeling in mice
Arun Jyothidasan, Sini Sunny, Asokan Devarajan, Aniqa Sayed, John Kofi Afortude, Brian K. Dalley, Vivek Nanda, Steven M. Pogwizd, Silvio Hector Litovsky, Joel Douglas Trinity et al. · 2024 · Redox Biology
Cryo-EM structure of the human Derlin-1/p97 complex reveals a hexameric channel in ERAD
Qian Wang, Deqiang Yao, Bing Rao, Ying Xia, Wenguo Li, Shaobai Li, Cao Mi, Yafeng Shen, An Qin, Yu Cao · 2025 · Communications Biology
Unraveling the regulatory role of endoplasmic-reticulum-associated degradation in tumor immunity
Xiaodan Qin, William D Denton, Leah N. Huiting, Kaylee S. Smith, Hui Feng · 2020 · Critical Reviews in Biochemistry and Molecular Biology
ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine
Varsha Venkatarangan, Weichao Zhang, Xi Yang, Jess G. Thoene, Si Houn Hahn, Ming Li · 2023 · Journal of Clinical Investigation
Expression of CLAVATA3 fusions indicates rapid intracellular processing and a role of ERAD
Francesca De Marchis, Sara Colanero, Eva M. Klein, Davide Mainieri, Viviana M. Prota, Michele Bellucci, Giampiero Pagliuca, Elisa Zironi, Teresa Gazzotti, Alessandro Vitale et al. · 2018 · Plant Science
A novel function of AAA-ATPase p97/VCP in the regulation of cell motility
Zi-Jia Khong, Soak-Kuan Lai, Cheng-Gee Koh, Susana Geifman Shochat, HY Li · 2020 · Oncotarget
p97 Inhibitor CB-5083 Blocks ERAD in Trypanosoma brucei
Paige Garrison, James D. Bangs · 2020 · Molecular and Biochemical Parasitology
Physical and Genetic Associations of the Irc20 Ubiquitin Ligase with Cdc48 and SUMO
Aaron D. Richardson, Richard G. Gardner, Gregory Prelich · 2013 · PLoS ONE
Various plus unique: Viral protein U as a plurifunctional protein for HIV-1 replication
Andrew Soper, Guillermo Juárez-Fernández, Hirofumi Aso, Miyu Moriwaki, Eri Yamada, Yusuke Nakano, Yoshio Koyanagi, Kei Sato · 2017 · Experimental Biology and Medicine
Ubiquitylation in the ERAD Pathway
Frederik Eisele, Antje Schäfer, Dieter H. Wolf · 2010 · Sub-cellular biochemistry/Subcellular biochemistry
Advances in the study of protein folding and endoplasmic reticulum-associated degradation in mammal cells
Hong Cao, Xuchang Zhou, Bowen Xu, Han Hu, Jianming Guo, Yuwei Ma, Miao Wang, Nan Li, Jun Zou · 2024 · Journal of Zhejiang University SCIENCE B
Characterization of a new AAA+ protein from archaea
Heike Summer, Roland Bruderer, Eilika U. Weber-Ban · 2006 · Journal of Structural Biology
Genome-wide identification and characterization of grapevine UFD1 genes during berry development and salt stress response
Lingzhu Wei, Jianhui Cheng, Xiang Wu Jiang, Jiang Wu · 2022 · Journal of Plant Biochemistry and Biotechnology
A Decade of Discovery—Eukaryotic Replisome Disassembly at Replication Termination
Rebecca M Jones, Alicja Reynolds-Winczura, Agnieszka Gambus · 2024 · Biology
Symmetry in normal modes and its strong dependence on symmetry in structure
Guang Song · 2017 · Journal of Molecular Graphics and Modelling
Unconventional p97/VCP-Mediated Endoplasmic Reticulum-to-Endosome Trafficking of a Retroviral Protein
Wendy Kaichun Xu, Yongqiang Gou, Mary M. Lozano, Jaquelin P. Dudley · 2021 · Journal of Virology
The AAA+ ATPase p97 as a novel parasite and tuberculosis drug target
George Kobakhidze, Ashish Sethi, Sepideh Valimehr, Stuart A. Ralph, Isabelle Rouiller · 2022 · Trends in Parasitology
Rescue of growth defects of yeast cdc48 mutants by pathogenic IBMPFD-VCPs
Takahiro Takata, Yoko Kimura, Yohei Ohnuma, Junko Kawawaki, Yukie Kakiyama, Keiji Tanaka, Akira Kakizuka · 2012 · Journal of Structural Biology
Analysis of Ubiquitin-Dependent Proteolysis in Caenorhabditis elegans
Alexandra Segref, Thorsten Hoppe · 2012 · Methods in molecular biology
Inhibition of p97/VCP function leads to defective autophagosome maturation, cell cycle arrest and apoptosis in mouse Sertoli cells
Sevil Çaylı, Cansu Sahin, Tuba Özdemir Sancı, Hilal Nakkaş · 2020 · Theriogenology
Non-permissive human conventional CD1c+ dendritic cells enable trans-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization
Mathieu Sikorski, Flora Coulon, Cécile Peltier, Cécile Braudeau, Alexandra Garcia, Matthieu Giraud, Karine Renaudin, Christine Kandel-Aznar, Steven Nédellec, Philippe Hulin et al. · 2021 · PLoS Pathogens
Probing Proteostatic Stress in Degenerating Photoreceptors Using Two ComplementaryIn VivoReporters of Proteasomal Activity
Paige M. Dexter, Ekaterina S. Lobanova, Stella Finkelstein, Vadim Y. Arshavsky · 2019 · eNeuro
Quality control of proteins in the mitochondrion
Mark Nolden, Brigitte Kisters–Woike, Thomas Langer, Martin Graef · 2006 · Springer eBooks
The derlin Dfm1 couples retrotranslocation of a folded protein domain to its proteasomal degradation
Daniela G. Vitali, Daniel Fonseca, Pedro Carvalho · 2024 · The Journal of Cell Biology
Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins
Amber M. Cheatham, Nishi Raj Sharma, Prasanna Satpute‐Krishnan · 2023 · The Journal of Cell Biology
Genome mining yields putative disease-associated ROMK variants with distinct defects
2023
Carbon disulfide induces accumulation of TDP-43 in the cytoplasm and mitochondrial dysfunction in rat spinal cords
Zhidan Liu, Yalong Qiang, Shulin Shan, Shuai Wang, Fuyong Song · 2024 · Cerebral Cortex
Mutant dominant-negative rhodopsin∆I256 causes protein aggregates degraded via ERAD and prevents normal rhodopsin from proper membrane trafficking
Bowen Cao, Johanna Valentina Dahlen, Merve Sen, Tina Beyer, Tobias Leonhard, Ellen Kilger, Blanca Arango‐González, Marius Ueffing · 2024 · Frontiers in Molecular Biosciences
The Role of the Ubiquitination Machinery in Dislocation and Degradation of Endoplasmic Reticulum Proteins
Marjolein Kikkert, Gerco C. Hassink, Emmanuel J. H. J. Wiertz · 2006 · Springer eBooks
Discovery of novel pyrimidine molecules containing boronic acid as VCP/p97 Inhibitors
Yonglei Zhang, Xiaomin Xie, Xueyuan Wang, Tiantian Wen, Chi Zhao, Hailong Liu, Bing Zhao, Yongqiang Zhu · 2021 · Bioorganic & Medicinal Chemistry
The role of atypical ubiquitination in cell regulation
О.А. Бунеева, A. E. Medvedev · 2017 · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry
Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors
Prabhakar Bastola, Rabeya Bilkis, Cristabelle De Souza, Kay T. Minn, JEREMY R. CHIEN · 2019 · Scientific Reports
VCP – the missing link in protein degradation?
Cezary Wójcik · 2002 · Trends in Cell Biology
Liver injury in α1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury
David H. Perlmutter · 2002 · Journal of Clinical Investigation
Introduction to the Proteasome and its Inhibitors
Alfred Lewis Goldberg · 2004 · Humana Press eBooks
Cdc48 (p97) and Its Cofactors
Alexander Buchberger · 2006
The SARS-CoV-2 accessory factor ORF7a downregulates MHC class I surface expression
Shuxuan Zheng, Hendrik de Buhr, Patrique Praest, Anouk Evers, Ingrid G. J. Boer, Mariëlle M.P. van Grinsven, Ylenia Longo, Liset de Vries, Wilco Nijenhuis, Lukas C. Kapitein et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen
Rachel Sharninghausen, Jiwon Hwang, Devon D. Dennison, Ryan D. Baldridge · 2023 · eLife
VCP controls KCC2 degradation through FAF1 recruitment and accelerates emergence from anesthesia
Peng Chen, Jiang-Jian Hu, Yuexin Liu, Boxu Cao, Xue‐Jun Song · 2024 · Proceedings of the National Academy of Sciences
2024 VCP International Conference: Exploring multi-disciplinary approaches from basic science of valosin containing protein, an AAA+ ATPase protein, to the therapeutic advancement for VCP-associated multisystem proteinopathy
A. Peck, Amal Dadi, Zollie Yavarow, Lindsay N. Alfano, Daniel J. Anderson, Michelle R. Arkin, Tsui‐Fen Chou, E.S. D'Ambrosio, Jordi Díaz‐Manera, Joseph P. Dudley et al. · 2025 · Neurobiology of Disease
Function and regulation of the mitochondrial stress response
Joshua B. Sheetz, Srividya Chandrasekhar, Michael Rapé · 2026 · Nature Structural & Molecular Biology
Single Site Suppressors of a Fission Yeast Temperature-Sensitive Mutant in cdc48 Identified by Whole Genome Sequencing
Irina N. Marinova, Jacob Engelbrecht, David Adrian Ewald, Lasse Løcke Langholm, Christian Holmberg, Birthe Brandt Kragelund, Colin Gordon, Olaf Nielsen, Rasmus Hartmann‐Petersen · 2015 · PLoS ONE
Proteomic analysis on Aspergillus strains that are useful for industrial enzyme production
Shinobu Takagi, Kaihei Kojima, Shinichi Ohashi · 2020 · Bioscience Biotechnology and Biochemistry
Valosin-containing protein-regulated endoplasmic reticulum stress causes NOD2-dependent inflammatory responses
Maryam Ghalandary, Yue Li, Thomas Fröhlich, Thomas Magg, Yanshan Liu, Meino Rohlfs, Sebastian Hollizeck, Raffaele Conca, Tobias Schwerd, Holm H. Uhlig et al. · 2022 · Scientific Reports
Aberrant DNA Polymerase α Is Excluded from the Nucleus by Defective Import and Degradation in the Nucleus
Christian S. Eichinger, Takeshi Mizuno, Keiko Mizuno, Y. Miyake, Ken‐ichiro Yanagi, Naoko Imamoto, Fumio Hanaoka · 2009 · Journal of Biological Chemistry
Characterization of WDR20: A new regulator of the ERAD machinery
Lingao Ju, Xiang Lin, Dong Yan, Qinglan Li, Min Wu, Lianyun Li · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction
Halley B. Rycenga, Kelly B. Wolfe, Elizabeth Shinmay Yeh, David T. Long · 2019 · Scientific Reports
Inner-nuclear-membrane–associated degradation employs Dfm1-independent retrotranslocation and alleviates misfolded transmembrane-protein toxicity
Matthew P. Flagg, Margaret A. Wangeline, Sarah R. Holland, Sascha H. C. Duttke, Christopher W. Benner, Sonya E. Neal, Randolph Y. Hampton · 2021 · Molecular Biology of the Cell
Viral Transport and Interaction with the Host Cytoskeleton
Manfred Heinlein · 2016 · Springer eBooks
Autophagy-Lysosome Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
Peter M. Sullivan, Xiaolai Zhou, Fenghua Hu · 2017 · InTech eBooks