Tubulin acetylation and cell motility
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MT acetylation by itself does not confer nocodazole resistance (stability) to microtubules.
“These data demonstrate that while nocodazole-resistant, stable MTs are acetylated, MT acetylation by itself does not confer nocodazole resistance (i.e., stability) to MTs, which is in agreement with earlier work (Palazzo et al., 2003; Fig. 2, A and B).”
From A live-cell marker to visualize the dynamics of stable microtubules throughout the cell cycle (2023) · cites this paper as Palazzo et al., 2003
Cites
HDAC6 is a microtubule-associated deacetylase
Hubbert, C., Guardiola, A., Shao, R., Kawaguchi, Y., Ito, A., Nixon, A., Yoshida, M., Wang, X.-F., & Yao, T.-P. (2002) · Nature · doi:10.1038/417455a · Cited by 2,403 · see citing works
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Haggarty, S. J., Koeller, K. M., Wong, J. C., Grozinger, C. M., & Schreiber, S. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0430973100 · Cited by 1,066 · see citing works
A live-cell marker to visualize the dynamics of stable microtubules throughout the cell cycle
Jansen, K. I., Iwanski, M. K., Burute, M., & Kapitein, L. C. (2023) · Journal of Cell Biology · doi:10.1083/jcb.202106105 · Cited by 39 · see citing works
Bohonowych, J. E., Peng, S., Gopal, U., Hance, M. W., Wing, S. B., Argraves, K. M., Lundgren, K., & Isaacs, J. S. (2011) · BMC Cancer · doi:10.1186/1471-2407-11-520 · Cited by 32 · see citing works
- Authors
- Palazzo, A., Ackerman, B., & Gundersen, G. G.
- Affiliations
- Columbia University (US)
- Corresponding author
- Gundersen, Gregg G.
- Venue
- Nature
- Published
- 2003-01-16
- Volume
- 421
- Issue
- 6920
- Pages
- 230-230
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2486272530
- Cited by
- 256
- References
- 1
- Citations by year
- 2026: 6 · 2025: 15 · 2024: 5 · 2023: 6 · 2022: 8 · 2021: 11 · 2020: 7 · 2019: 7 · 2018: 14 · 2017: 15 · 2016: 11 · 2015: 13 · 2014: 11 · 2013: 16 · 2012: 6
- FWCI
- 4.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Histone Deacetylase Inhibitors Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Keywords
- tubulin acetylation, cell motility, HDAC6, microtubule stability, post-translational modification, microtubules
- MeSH terms
- Histone Deacetylase 6, Acetylation, Animals, Cell Movement, Half-Life, Histone Deacetylases, Hydroxamic Acids, Lysophospholipids, Microtubules, Tubulin, Nocodazole, 3T3 Cells, Mice, Histone Deacetylase Inhibitors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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