Mutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 mice

Liu, Xinran, Ondek, Brian, Williams, David S.·1998·Nature Genetics
DOI 10.1038/470

Cited by (167)

Items 101–167 of 167

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  2. Identification of a Rat Model for Usher Syndrome Type 1B by N-Ethyl-N-nitrosourea Mutagenesis-Driven Forward Genetics
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  4. Identification and localization of myosin superfamily members in fish retina and retinal pigmented epithelium
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  5. Myrip uses distinct domains in the cellular activation of myosin VA and myosin VIIA in melanosome transport
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  6. Usher syndrome: a review of the clinical phenotype, genes and therapeutic strategies
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  7. Association of kinesin and myosin with pigment granules in crustacean chromatophores
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  8. Molecular genetics of Usher syndrome
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  9. The contribution of exogenous and endogenous mutagens to in vivo mutations
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  10. Myosin VIIA is a Marker for the Cone Accessory Outer Segment in Zebrafish
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  11. Actin-dependent motility of melanosomes from fish retinal pigment epithelial (RPE) cells investigated using in vitro motility assays
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  12. Gene therapy approaches for prevention of retinal degeneration in Usher syndrome
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  13. Actin-Binding Proteins and Disease
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  14. Hypomelanosis, immunity, central nervous system: No more “and”, not the end
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  15. Functional and morphological analysis of the subretinal injection of retinal pigment epithelium cells
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  16. Mice as Models for Human Hereditary Deafness
    Karen P. Steel, Alexandra Erven, Amy E. Kiernan · 2006 · Springer eBooks
  17. Impacts of Usher Syndrome Type IB Mutations on Human Myosin VIIa Motor Function
    Shinya Watanabe, Nobuhisa Umeki, Reiko Ikebe, Mitsuo Ikebe · 2008 · Biochemistry
  18. Genotype–phenotype correlation in patients with Usher syndrome and pathogenic variants in MYO7A: implications for future clinical trials
    Lilián Galbis‐Martínez, Fiona Blanco‐Kelly, Gema García‐García, Almudena Ávila‐Fernández, Teresa Jaijo, Carla Fuster‐García, Irene Perea‐Romero, Olga Zurita, Belén Jimenez‐Rolando, Ester Carreño et al. · 2021 · Acta Ophthalmologica
  19. The Cellular Function of the Usher Gene Product Myosin VIIa is Specified by Its Ligands
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  20. Expression profiling of the retina of pde6c, a zebrafish model of retinal degeneration
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  21. Orientation of actin filaments in teleost retinal pigment epithelial cells, and the effect of the lectin, Concanavalin A, on melanosome motility
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  22. Animal Models, in “The Quest to Decipher RPE Phagocytosis”
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  23. Expression of two major isoforms of MYO7A in the retina: Considerations for gene therapy of Usher syndrome type 1B
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  24. Autosomal and X-Linked Auditory Disorders
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  26. Coincident Onset of Expression of Myosin VIIa and Opsin in the Cilium of the Developing Photoreceptor Cell
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  28. Microtubule Motor Transport of Organelles in a Specialized Epithelium: The RPE
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  29. Expression of constructs of the neuronal isoform of myosin‐Va interferes with the distribution of melanosomes and other vesicles in melanoma cells
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  31. CRISPR-Cas9 Engineered Extracellular Vesicles for the Treatment of Dominant Progressive Hearing Loss
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  32. Extracellular vesicle–mediated gene editing for the treatment of nonsyndromic progressive hearing loss in adult mice
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  36. Mammalian Cochlear Genes and Hereditary Deafness
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  38. Unconventional myosins at the crossroad of signal transduction and cytoskeleton remodeling
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  41. Detailed Clinical, Ophthalmic, and Genetic Characterization of MYO7A -Associated Usher Syndrome
    Juan Carlos Romo-Aguas, Thales A. C. de Guimarães, Angelos A. Kalitzeos, Nancy Aychoua, Chrysanthi Tsika, Anthony G. Robson, Yu Fujinami‐Yokokawa, Kaoru Fujinami, Omar A. Mahroo, Andrew R. Webster et al. · 2025 · Investigative Ophthalmology & Visual Science
  42. Modeling Retinal Diseases Using Genetic Approaches in Mice
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  43. Myosin VII
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  44. Transport and Distribution of Melanosomes
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  46. Identifying and Overcoming Challenges in Developing Effective Treatments for Usher 1B: A Workshop Report
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  47. Sequence Alignment-Based Prediction of Myosin 7A: Structural Implications and Protein Interactions
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  48. Retinal Degeneration in Usher Syndrome
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  57. MERTK-mediated Signaling in the Retinal Pigment Epithelium: Insights into the Mechanism of RPE Phagocytosis.
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  58. Genetyczne podłoże zespołu Ushera w kontekście patologii molekularnej narządu słuchu i wzroku
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  59. 22 Hereditary Hearing Impairment
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  61. Investigating auditory transduction functions of myosin VII in Drosophila melanogaster
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  62. References
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