Cited by 8

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Drug development: Through the barrier

DeWeerdt, Sarah·2016·Nature

Overview

Integrity signals

Registry

Crossref · 10.1038/537s154a

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • TPT-172 crosses the blood-brain barrier in mice, inferred from similarity to other small pharmacological chaperones.

    “Although we do not have data showing that the pharmacological chaperone we used in our study has crossed the blood-brain barrier in our mice, we are confident that this is the case based on the similarity with other small pharmacological chaperones, most of which are predicted to have a good brain permeability [18, 19].”

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Metadata

Authors
DeWeerdt, S.
Venue
Nature
Published
2016-09-21
Volume
537
Issue
7621
Pages
S154-S157
ISSN
  • 0028-0836
  • 1476-4687
Cited by
8
References
1
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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