Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

Chui, De-Hua, Tanahashi, Hiroshi, Ozawa, Kazuharu, Ikeda, Sachiya, Checler, Frédéric, Ueda, Otoya, Suzuki, Hiroshi, Araki, Wataru +5 more·1999·Nature Medicine

DOI 10.1038/8438

Cited by (364)

Items 201–300 of 364

Age-related plaque morphology and C-terminal heterogeneity of amyloid β in Dutch-type hereditary cerebral hemorrhage with amyloidosis
Marion L. C. Maat–Schieman, Hirokazu YAMAGUCHI, Sjoerd G. van Duinen, Remco Natté, Raymund A.C. Roos · 2000 · Acta Neuropathologica
Time Course of Glucose Metabolism in Relation to Cognitive Performance and Postmortem Neuropathology in Met146Val PSEN1 Mutation Carriers
Michael Schöll, Ove Almkvist, Nenad Bogdanović, Anders E. Wall, Bengt Långström, Matti H. Viitanen, Agneta K. Nordberg · 2011 · Journal of Alzheimer s Disease
An Alzheimer's disease hypothesis based on transcriptional dysregulation
Nikolaos K. R K Robakis · 2003 · Amyloid
Early changes in neurons of the hippocampus and neocortex in transgenic rats expressing intracellular human a-β
Emilio M. Serrano-López, Karen F. S. Bell, Alfredo Ribeiro‐da‐Silva, A. Claudio Cuello · 2004 · Journal of Alzheimer s Disease
Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid
Yasumasa Ohyagi, Yuko Tsuruta, Kyoko Motomura, Katsue Miyoshi, Hitoshi Kikuchi, Toru Iwaki, Takayuki Taniwaki, Jun‐ichi Kira · 2006 · Journal of Neuroscience Methods
Intraneuronal advanced glycation endproducts in presenilin-1 Alzheimer??s disease
Gerald M nch, Claire E. Shepherd, Heather McCann, William S. Brooks, John B. Kwok, Thomas Arendt, Marianne Hallupp, Peter R. Schofield, Ralph Nigel Martins, Glenda Margaret Halliday · 2002 · Neuroreport
Why therapies for Alzheimer’s disease do not work: Do we have consensus over the path to follow?
Zareen Amtul · 2015 · Ageing Research Reviews
Dysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosis
Rachael L. Neve, Donna L. McPhie · 2006 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Caenorhabditis elegans as a model organism to study APP function
Collin Y. Ewald, Chris Li · 2011 · Experimental Brain Research
Overview on Rodent Models of Alzheimer's Disease
Jean‐Cosme Dodart, Patrick C. May · 2005 · Current Protocols in Neuroscience
Secreted Aβ Does Not Mediate Neurotoxicity by Antibody-Stimulated Amyloid Precursor Protein
Haruka Sudo, Yuichi Hashimoto, Takako Niikura, Zongjun Shao, Takashi Yasukawa, Yuko Ito, Marina Yamada, Michihiro Hata, Takako Hiraki, Masaoki Kawasumi et al. · 2001 · Biochemical and Biophysical Research Communications
What Can Rodent Models Tell Us About Cognitive Decline in Alzheimer's Disease?
Sabrina Davis, Serge Laroche · 2003 · Molecular Neurobiology
Intracellularly generated amyloid‐β peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells
Luke Esposito, Li Gan, Gui-Qiu Yu, Christian Essrich, Lennart Mucke · 2004 · Journal of Neurochemistry
Presenilin-1 Protects against Neuronal Apoptosis Caused by Its Interacting Protein PAG
Yan Zhou, Wanjiang Zhang, Rachael Easton, James W. Ray, Patricia A. Lampe, Zhi‐Hong Jiang, Anne L. Brunkan, Alison Goate, Eugene M. Johnson, Jane Y. Wu · 2002 · Neurobiology of Disease
Intracellular Aβ is increased by okadaic acid exposure in transfected neuronal and non-neuronal cell lines
Xiaoyan Sun, Gregory M. Cole, Teresa Chu, Weiming Xia, Douglas Galasko, Haruyasu Yamaguchi, Kentaro Tanemura, Sally Ann Frautschy, Akihiko Takashima · 2002 · Neurobiology of Aging
Targeting STAT3 signaling pathway in the treatment of Alzheimer’s disease with compounds from natural products
Xiyue Wen, Jinyue Hu · 2024 · International Immunopharmacology
Gene-Environment Interaction Research and Transgenic Mouse Models of Alzheimer's Disease
Leonidas Chouliaras, Annerieke S. R. Sierksma, Günter Kenis, Jos Prickaerts, Marijke A.M. Lemmens, Ivona Brasnjevic, Eva L. van Donkelaar, Pilar Martínez‐Martínez, Mario H. Losen, Marc H. De Baets et al. · 2010 · International Journal of Alzheimer s Disease
Possible mechanisms of APP-mediated oxidative stress in Alzheimer’s disease1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.
Gerd Multhaup, Stefan Scheuermann, Andrea Schlicksupp, Andreas Simons, Markus Strauss, André Kemmling, Christian Oehler, Roberto Cappai, Rüdiger Pipkorn, Thomas A. Bayer · 2002 · Free Radical Biology and Medicine
Mechanisms of Aβ Clearance and Catabolism
Suzanne Y. Guénette · 2003 · NeuroMolecular Medicine
Loss of nicastrin elicits an apoptotic phenotype in mouse embryos
Van Nguyen, Cynthia E Hawkins, Catherine Bergeron, Agnes Supala, Jean Huang, David A. Westaway, Peter St George‐Hyslop, Richard F. Rozmahel · 2006 · Brain Research
Modulatory effect of methylsulfonylmethane against BPA/γ-radiation induced neurodegenerative alterations in rats: Influence of TREM-2/DAP-12/Syk pathway
Mohamed Khairy Abdel-Rafei, Noura Magdy Thabet · 2020 · Life Sciences
Autophagy is involved in oral rAAV/Aβ vaccine-induced Aβ clearance in APP/PS1 transgenic mice
He-Cheng Wang, Tao Zhang, Bolati Kuerban, Ying-Lan Jin, Weidong Le, Hideo Hara, Dong-Sheng Fan, Yan‐Jiang Wang, Takeshi Tabira, De-Hua Chui · 2015 · Neuroscience Bulletin
Intracellular Calcium Deficits in Drosophila Cholinergic Neurons Expressing Wild Type or FAD-Mutant Presenilin
Kinga Michno, David Knight, Jorge M. Campusano, Diana L. van de Hoef, Gabrielle L. Boulianne · 2009 · PLoS ONE
Presenilin 1 and Cadherins: Stabilization of Cell-Cell Adhesion and Proteolysis-Dependent Regulation of Transcription
Loukia Parisiadou, Angeliki Fassa, Angeliki Fotinopoulou, Ioanna Bethani, Spiros Efthimiopoulos · 2004 · Neurodegenerative Diseases
Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1
Y. Gerakis, J. Dunys, Charlotte Bauer, F. Checler · 2016 · Scientific Reports
Increased Tau Phosphorylation and Impaired Presynaptic Function in Hypertriglyceridemic ApoB-100 Transgenic Mice
Nikolett Lénárt, Viktor Szegedi, Gábor Juhász, Aniko Kasztner, János Horváth, Erika Bereczki, Melinda E. Tóth, Botond Penke, Miklós Sántha · 2012 · PLoS ONE
Caspase-3-mediated cleavage of PHF-1 tau during apoptosis irrespective of excitotoxicity and oxidative stress: an implication to Alzheimer's disease
Hyo Jung Kang, Won Joo Yoon, Gyeong Joon Moon, Doo Yeon Kim, Seonghyang Sohn, Hyuk Jae Kwon, Byoung Joo Gwag · 2005 · Neurobiology of Disease
Intraneuronally injected amyloid beta inhibits long-term potentiation in rat hippocampal slices
Izumi Nomura, Hajime Takechi, Nobuo Kato · 2012 · Journal of Neurophysiology
β-Amyloid and α-Synuclein Cooperate To Block SNARE-Dependent Vesicle Fusion
Bong-Kyu Choi, Jae-Yeol Kim, Moon-Yong Cha, Inhee Mook‐Jung, Yeon-Kyun Shin, Nam Ki Lee · 2015 · Biochemistry · Retracted
The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb
Sun, Miao, Asghar, Suwaiba Z., Zhang, Huaye · 2016 · Neurobiology of Disease
Phospholipid transfer protein (PLTP) deficiency accelerates memory dysfunction through altering amyloid precursor protein (APP) processing in a mouse model of Alzheimer's disease
Yawei Tong, Yang Sun, Xiaosheng Tian, Ting Zhou, Hecheng Wang, Tao Zhang, Rui Zhan, Lei Zhao, Bolati Kuerban, Zhengqian Li et al. · 2015 · Human Molecular Genetics
A Direct Interaction between Transforming Growth Factor (TGF)-βs and Amyloid-β Protein Affects Fibrillogenesis in a TGF-βReceptor-independent Manner
Darrell D. Mousseau, Sarah Chapelsky, Grégory De Crescenzo, Marina D. Kirkitadze, Joanne Magoon, Sadayuki Inoué, David B. Teplow, Maureen D. O'Connor‐McCourt · 2003 · Journal of Biological Chemistry
Ambrosin, a potent NF-κβ inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin
Khalil, Mohammed N. A., Choucry, Mouchira A., El Senousy, Amira S., Hassan, Azza, El-Marasy, Salma A., El Awdan, Sally A., Omar, Farghaly A. · 2019 · PLOS ONE
Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer's disease
Gary L. Odero, K. Oikawa, Kathryn A. C. Glazner, Jason Schapansky, Denise Grossman, Jonathan Dale Thiessen, Anna Motnenko, N. Ge, Melanie Martin, Gordon W. Glazner et al. · 2010 · Neuroscience
Galanin Protects Against Intracellular Amyloid Toxicity in Human Primary Neurons
Jia Cui, Qiuyue Chen, Xiaojing Yue, Xuejun Jiang, George F. Gao, Long‐Chuan Yu, Yan Zhang · 2010 · Journal of Alzheimer s Disease
Review: Omega-3 and Memory Function: To Eat or Not To Eat
Imose Itua, Ebrahim Khalil Naderali · 2010 · American Journal of Alzheimer s Disease & Other Dementias®
HH Domain of Alzheimer’s Disease Aβ Provides Structural Basis for Neuronal Binding in PC12 and Mouse Cortical/Hippocampal Neurons
Joseph F. Poduslo, Emily J. Gilles, Muthu Ramakrishnan, Kyle G. Howell, Thomas M. Wengenack, Geoffry L. Curran, Karunya K. Kandimalla · 2010 · PLoS ONE
Protein Aggregation and Polyasparagine-Mediated Cellular Toxicity inSaccharomyces cerevisiae
Theodore W. Peters, Mingxia Huang · 2007 · Prion
Protective Role Of Apigenin Against Aβ25-35 Toxicity Via Inhibition Of Mitochondrial Cytochrome C Release
Farnaz Nikbakht, Yasaman Khadem, Sobhan Haghani, Hadiseh Hoseininia, Moein Sadat Alireza, Paria Hashemi, Nida Jamali · 2019 · Basic and Clinical Neuroscience Journal
Platelet as a physiological model to investigate apoptotic mechanisms in Alzheimer β-amyloid peptide production
Tiziana Casoli, Giuseppina Di Stefano, Belinda Giorgetti, Marta Balietti, Rina Recchioni, Fausto Moroni, Fiorella Marcheselli, Gianni Bernardini, Patrizia Fattoretti, Carlo Bertoni–Freddari · 2007 · Mechanisms of Ageing and Development
Zinc Enhances Synthesis of Presenilin 1 in Mouse Primary Cortical Culture
In-Ho Park, Min Whan Jung, Hiroshi Mori, Inhee Mook‐Jung · 2001 · Biochemical and Biophysical Research Communications
Omi is a mammalian heat-shock protein that selectively binds and detoxifies oligomeric amyloid-β
Meng-Lu Liu, Ming-Jie Liu, Yan-Fei Shen, Hoon Ryu, Hyeon‐Jin Kim, Kristina Klupsch, Julian Downward, Seong‐Tshool Hong · 2009 · Journal of Cell Science
Cellular FLICE-like Inhibitory Protein (c-FLIP) and PS1-associated Protein (PSAP) Mediate Presenilin 1-induced γ-Secretase-dependent and -independent Apoptosis, Respectively
Linlin Zeng, Hu Chen, Fuqiang Zhang, Daniel C. Xu, Mei‐Zhen Cui, Xuemin Xu · 2015 · Journal of Biological Chemistry
Patient-Derived Fibroblasts With Presenilin-1 Mutations, That Model Aspects of Alzheimer’s Disease Pathology, Constitute a Potential Object for Early Diagnosis
Gustavo López-Toledo, Maria‐del‐Carmen Silva‐Lucero, Jorge Herrera‐Díaz, David-Erasmo García, José‐Antonio Arias‐Montaño, María del Carmen Cárdenas‐Aguayo · 2022 · Frontiers in Aging Neuroscience
Reduction in CHT1-mediated choline uptake in primary neurons from presenilin-1 M146V mutant knock-in mice
Daniel J. Payette, Jun Xie, Qing Guo · 2006 · Brain Research
Animal models of cognitive dysfunction
Seyed Khosrow Tayebati · 2005 · Mechanisms of Ageing and Development
Early molecular events of autosomal‐dominant Alzheimer's disease in marmosets with PSEN1 mutations
Gregg E. Homanics, Jung Eun Park, Lauren S. Bailey, David J. Schaeffer, Lauren K Hayrynen Schaeffer, Jie He, Shuoran Li, Tingting Zhang, Annat Haber, Catrina A. Spruce et al. · 2024 · Alzheimer s & Dementia
Transgenic Models of Alzheimer's Disease
Michael C. Sugarman, Steven F. Hinton, Frank M. LaFerla · 2001 · Humana Press eBooks
Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis
Eric Cruz, Sushil Kumar K, Li Yuan, Jyothi Arikkath, Surinder K. Batra · 2018 · PLoS ONE
Effects of Huperzin-A on the Beta-amyloid accumulation in the brain and skeletal muscle cells of a rat model for Alzheimer's disease
Çağatay Han Türkseven, Belgin Buyukakilli, Ebru Ballı, Derya Yetkin, Mehmet Emin Erdal, Şenay Görücü Yılmaz, Leyla Şahin · 2017 · Life Sciences
Animal Models of Dementia
Dong‐Hee Choi, Jongmin Lee · 2011 · Brain & Neurorehabilitation
Markers of apoptosis and models of programmed cell death in Alzheimer’s disease
Jacques Hugon, Faraj Terro, F. Esclaire, Catherine Yardin · 2000 · Springer eBooks
Specific downregulation of presenilin 2 gene expression is prominent during early stages of sporadic late-onset Alzheimer’s disease
Pamela J. McMillan, James B. Leverenz, Daniel M. Dorsa · 2000 · Molecular Brain Research
Chronic stress-mutated presenilin 1 gene interaction perturbs neurogenesis and accelerates neurodegeneration
Shohko Kunimoto, Shun Nakamura, Keiji Wada, Takayoshi Inoue · 2009 · Experimental Neurology
Regional brain evaluation of acetylcholinesterase activity in PS1/A246E transgenic mice
Rozat Jazi, Robert Lalonde, Sue Qian, C. Strazielle · 2008 · Neuroscience Research
The Emerging Role of Proteolysis in Mitochondrial Quality Control and the Etiology of Parkinson’s Disease
Riya Shanbhag, Guang Shi, Jarungjit Rujiviphat, G. Angus McQuibban · 2012 · Parkinson s Disease
The Amyloid β Protein
Noel D. Lazo, Samir Kumar Maji, Erica A. Fradinger, Gal Bitan, David B. Teplow · 2005 · Wiley eBooks
In-Depth Characterization of Endo-Lysosomal Aβ in Intact Neurons
Alec K. McKendell, Mei CQ Houser, Shane P. C. Mitchell, Michael S. Wolfe, Oksana Berezovska, Masato Maesako · 2022 · Biosensors
The application of patient-derived induced pluripotent stem cells for modeling and treatment of Alzheimer’s disease
Fabin Han, Chuanguo Liu, Jin Huang, Juanli Chen, Chuanfei Wei, Xiwen Geng, Yanming Liu, Dong Han, Mengpeng Li · 2019 · Brain Science Advances
Molecular dynamics studies of α-helix stability in fibril-forming peptides
Erik Nordling, Yvonne Kallberg, Jan Johansson, Bengt Persson · 2007 · Journal of Computer-Aided Molecular Design
Increase in p53 Protein Levels by Presenilin 1 Gene Mutations and its Inhibition by Secretase Inhibitors
Linqing Ma, Yasumasa Ohyagi, Katsue Miyoshi, Nobutaka Sakae, Kyoko Motomura, Takayuki Taniwaki, Hirokazu Furuya, Kazuya Takeda, Takeshi Tabira, Jun‐ichi Kira · 2009 · Journal of Alzheimer s Disease
Correlation between β-amyloid peptide production and human APP-induced neuronal death
Pascal Kienlen‐Campard, Jean‐Noël Octave · 2002 · Peptides
The Nuclear Inclusion a (NIa) Protease of Turnip Mosaic Virus (TuMV) Cleaves Amyloid-β
Hye-Eun Han, Saravanan Sellamuthu, Bae Hyun Shin, Yong‐Jae Lee, Sungmin Song, Ji-Seon Seo, In‐Sun Baek, Jeomil Bae, Hannah Kim, Yung Joon Yoo et al. · 2010 · PLoS ONE
Shengmai Formula Ameliorates Pathological Characteristics in AD C. elegans
Weimin Zhang, Dejuan Zhi, Hui Jun Ren, Dong Wang, Xin Wang, Zhan‐Xin Zhang, Dong‐Qing Fei, Hongmei Zhu, Hongyu Li · 2016 · Cellular and Molecular Neurobiology
Comparing the Efficacy of Anodal, Cathodal, and Sham Transcranial Direct Current Stimulation on Brain-derived Neurotrophic Factor and Psychological Symptoms in Opioid-addicted Patients
Zakaria Eskandari, Mohsen Dadashi, Hossein Mostafavi, Alireza Armani Kia, Reza Pirzeh · 2019 · Basic and Clinical Neuroscience Journal
Increased Phosphorylation of Tau and Synaptic Protein Loss in the Aged Transgenic Mice Expressing Familiar Alzheimer’s Disease-Linked Presenilin 1 Mutation
Xifei Yang, Ying Yang, Jianjun Liu, Geng Li, Edward S. Yang · 2011 · Neurochemical Research
Cellular strategies to cope with protein aggregation
Annika Scior, Katrin Juenemann, Janine Kirstein · 2016 · Essays in Biochemistry
The neuroprotective mechanism of cinnamaldehyde against amyloid-β in neuronal SHSY5Y cell line: The role of N-methyl-D-aspartate, ryanodine, and adenosine receptors and glycogen synthase kinase-3β.
Masoumeh Emamghoreishi, Majid Reza Farrokhi, Atena Amiri, Mojtaba Keshavarz · 2019 · PubMed Central
Targeting antigen-specific receptors on B lymphocytes to generate high yields of specific monoclonal antibodies directed against biologically active lower antigenic peptides within presenilin 1
Masahiro Tomita, Hiroyuki Sugi, Kazuharu Ozawa, Tian Yow Tsong, Tetsuro Yoshimura · 2001 · Journal of Immunological Methods
Acquired expression of mutant Mitofusin 2 causes progressive neurodegeneration and abnormal behavior
Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada · 2019 · Journal of Neuroscience
Evidence for the accumulation of Abeta immunoreactive material in the human brain and in transgenic animal models
A. Claudio Cuello, Simon Allard, Maria Teresa Ferretti · 2012 · Life Sciences
Production of β-amyloid by primary human foetal mixed brain cell cultures and its modulation by exogenous soluble β-amyloid
G.M Hayes, David R Howlett, George Edward Griffin · 2002 · Neuroscience
When the DREAM is gone: from basic science to future prospectives in pain management and beyond
Hai‐Ying Mary Cheng, Josef Martin Penninger · 2003 · Expert Opinion on Therapeutic Targets
Caffeine Neuroprotective Mechanism Against β-Amyloid Neurotoxicity in SHSY5Y Cell Line: Involvement of Adenosine, Ryanodine, and N-Methyl-D-Aspartate Receptors
Mojtaba Keshavarz, Majid Reza Farrokhi, Atena Amiri · 2017 · Advanced Pharmaceutical Bulletin
The three sisters of fate: Genetics, pathophysiology and outcomes of animal models of neurodegenerative diseases
Michael Klonarakis, Maya De Vos, Emma K. Woo, Liam T. Ralph, Jonathan S. Thacker, Joana Gil‐Mohapel · 2022 · Neuroscience & Biobehavioral Reviews
Role of insulin in Alzheimer's disease:approaches emerging from basic animal research and neurocognitive studies in humans
Werner Kern, Jan Born A, Horst Lorenz Fehm · 2002 · Drug Development Research
Type-specific evolution of amyloid plaque and angiopathy in APPsw mice
Yasuo Harigaya, Yasushi Tomidokoro, Masaki Ikeda, Atsushi Sasaki, Takeshi Kawarabayashi, Etsuro Matsubara, Mitsuyasu Kanai, Takaomi C. Saido, Steven G. Younkin, Mikio Shoji · 2005 · Neuroscience Letters
Precocious emergence of cognitive and synaptic dysfunction in 3xTg-AD mice exposed prenatally to ethanol
Adelaide R. Tousley, Pamela W. L. Yeh, Hermes H. Yeh · 2022 · Alcohol
Establishment of experimental models for Alzheimer's disease research
Yunlong Li · 2013 · International Journal of Neuroscience
Alzheimer’s Disease and Its Possible Evolutionary Origin: Hypothesis
James F. Whitfield, Kerry Rennie, Balu Chakravarthy · 2023 · Cells
Antidepressants Modulate Intracellular Amyloid Peptide Species in N2a Neuroblastoma Cells
Marwa A. Aboukhatwa, Yuan Luo · 2011 · Journal of Alzheimer s Disease
Fighting the Cause of Alzheimer’s and GNE Myopathy
Shreedarshanee Devi, Rashmi Yadav, Pratibha Chanana, Ranjana Arya · 2018 · Frontiers in Neuroscience
Trans-Differentiation of Human Dental Pulp Stem Cells Into Cholinergic-Like Neurons Via Nerve Growth Factor
Shahram Darabi, Taki Tiraihi, Maryam Nazm Bojnordi, Hatef Ghasemi Hamidabadi, Nourollah Rezaei, Maria Zahiri, Rafieh Alizadeh · 2019 · Basic and Clinical Neuroscience Journal
Molecular and cell biological aspects of Alzheimer disease
B.S. Shastry · 2001 · Journal of Human Genetics
Consequence of Dementia and Cognitive Impairment by Primary Nucleation Pathway
Aditya Singh, Valeed Ahmad Ansari, Tarique Mahmood Ansari, Syed Misabah Hasan, Farogh Ahsan, Kuldeep Singh, Rufaida Wasim, Shubhrat Maheshwari, Asad Ahmad · 2023 · Hormone and Metabolic Research
Research progress in animal models and stem cell therapy for Alzheimer’s disease
Fabin Han, Wei Wang, Chao Chen · 2014 · Journal of Neurorestoratology
Untangling Alzheimer's disease from fibrous lesions of neurofibrillary tangles and senile plaques
Hiroshi Mori · 2000 · Neuropathology
Biomarker identification in neurologic diseases: improving diagnostics and therapeutics
Keith D. Coon, Travis L. Dunckley, Dietrich A. Stephan · 2004 · Expert Review of Molecular Diagnostics
PS1 knockin mice with the Japanese I213T mutation: Effects on exploratory activity, motor coordination, and spatial learning
Robert Lalonde, C. Strazielle · 2005 · Behavioural Brain Research
Heat Shock Proteins and Neurodegenerative Diseases
Ian R. Brown · 2007 · Springer eBooks
Detection of the Presenilin 1 COOH-Terminal Fragment in the Extracellular Compartment: A Release Enhanced by Apoptosis
Luisa Benussi, Antonella Alberici, Manuel Mayhaus, Uwe Langer, Roberta Ghidoni, Federica Mazzoli, Francesca M. Nicosia, Laura Barbiero, Giovanni Battista Frisoni, Orazio Oz. Zanetti et al. · 2001 · Experimental Cell Research
Abnormal cross‐talk between mutant presenilin 1 ( I143T, G384A ) and glycosphingolipid biosynthesis
Tatsuro Mutoh, Naoki Kawamura, Yoshio Hirabayashi, Sayuri Shima, Tadayuki Miyashita, Shinji Ito, Kunihiko Asakura, Wataru Araki, Emanuela Cazzaniga, Eri Muto et al. · 2012 · The FASEB Journal
Animal Models in Biomedical Research
Fred William Quimby · 2002 · Elsevier eBooks
Ethanol Effects on the Cytoskeleton of Nerve Tissue Cells
Sergio Gustavo Evrard, Alicia Brusco · 2010 · Advances in neurobiology
Pathological Calcium Signaling in Traumatic Brain Injury and Alzheimer’s Disease: From Acute Neuronal Injury to Chronic Neurodegeneration
Stephan Neuschmid, Carla Schallerer, Barbara E. Ehrlich, Declan McGuone · 2025 · International Journal of Molecular Sciences
Comparing the Effectiveness of Neurofeedback and Transcranial Direct Current Stimulation on Sleep Quality of Patients With Migraine
Zahra Kosari, Mohsen Dadashi, Mahdi Maghbouli, Hossein Mostafavi · 2019 · Basic and Clinical Neuroscience Journal
Fe3+ Facilitates Endocytic Internalization of Extracellular Aβ1–42 and Enhances Aβ1–42-Induced Caspase-3/Caspase-4 Activation and Neuronal Cell Death
Tomoyuki Nishizaki · 2018 · Molecular Neurobiology
Resolution of Carvedilol's Conformational Surface via Gas and Solvent Phase Density Functional Theory Optimizations and NMR Spectroscopy
David R. P. Almeida, Donna M. Gasparro, Tamás A. Martinek, Ferenc Fülöp, Imre G. Csizmadia · 2004 · The Journal of Physical Chemistry A
Amyloid β peptide binds a novel death‐inducing protein, AB‐DIP
Madepalli Krishnappa Lakshmana, Wataru Araki, Takeshi Tabira · 2005 · The FASEB Journal
Correction: Intracellular Calcium Deficits in Drosophila Cholinergic Neurons Expressing Wild Type or FAD-Mutant Presenilin
Kinga Michno, David Knight, Jorge M. Campusano, Diana L. van de Hoef, Gabrielle L. Boulianne · 2009 · PLoS ONE