The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The DNA sequence of human chromosome 22
Open accessAbstract
Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to defining its genetic components. The genomic sequence provides access to the complete structures of all genes, including those without known function, their control elements, and, by inference, the proteins they encode, as well as all other biologically important sequences. Furthermore, the sequence is a rich and permanent source of information for the design of further biological studies of the organism and for the study of evolution through cross-species sequence comparison. The power of this approach has been amply demonstrated by the determination of the sequences of a number of microbial and model organisms. The next step is to obtain the complete sequence of the entire human genome. Here we report the sequence of the euchromatic part of human chromosome 22. The sequence obtained consists of 12 contiguous segments spanning 33.4 megabases, contains at least 545 genes and 134 pseudogenes, and provides the first view of the complex chromosomal landscapes that will be found in the rest of the genome.
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Cites
Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669
Cited by
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
Self-citationThe sequence of the human genome
Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
The Human Genome Browser at UCSC
Kent, W. J., Sugnet, C. W., Furey, T. S., Roskin, K. M., Pringle, T. H., Zahler, A. M., & Haussler, A. D. (2002) · Genome Research · doi:10.1101/gr.229102 · Cited by 10,400
<tt>BLAT</tt> —The <tt>BLAST</tt> -Like Alignment Tool
Kent, W. J. (2002) · Genome Research · doi:10.1101/gr.229202 · Cited by 8,480
Initial sequencing and comparative analysis of the mouse genome
Mouse Genome Sequencing Consortium (2002) · Nature · doi:10.1038/nature01262 · Cited by 7,187
Metadata
- Authors
- Dunham, I., Hunt, A. R., Collins, J. E., Bruskiewich, R., Beare, D. M., Clamp, M., Smink, L. J., Ainscough, R., Almeida, J. P., Babbage, A., Bagguley, C., Bailey, J., Barlow, K., Bates, K. N., Beasley, O., Bird, C. P., Blakey, S., Bridgeman, A. M., Buck, D., Burgess, J., Burrill, W. D., Burton, J., Carder, C., Carter, N. P., Chen, Y., Clark, G., Clegg, S. M., Cobley, V., Cole, C. G., Collier, R. E., Connor, R. E., Conroy, D., Corby, N., Coville, G. J., Cox, A. V., Davis, J., Dawson, E., Dhami, P. D., Dockree, C., Dodsworth, S. J., Durbin, R. M., Ellington, A., Evans, K. L., Fey, J. M., Fleming, K., French, L., Garner, A. A., Gilbert, J. G. R., Goward, M. E., Grafham, D., Griffiths, M. N., Hall, C., Hall, R., Hall-Tamlyn, G., Heathcott, R. W., Ho, S., Holmes, S., Hunt, S. E., Jones, M. C., Kershaw, J., Kimberley, A., King, A., Laird, G. K., Langford, C. F., Leversha, M. A., Lloyd, C., Lloyd, D. M., Martyn, I. D., Mashreghi-Mohammadi, M., Matthews, L., McCann, O. T., McClay, J., McLaren, S., McMurray, A. A., Milne, S. A., Mortimore, B. J., Odell, C. N., Pavitt, R., Pearce, A. V., Pearson, D., Phillimore, B. J., Phillips, S. H., Plumb, R. W., Ramsay, H., Ramsey, Y., Rogers, L., Ross, M. T., Scott, C. E., Sehra, H. K., Skuce, C. D., Smalley, S., Smith, M. L., Soderlund, C., Spragon, L., Steward, C. A., Sulston, J. E., Swann, R. M., Vaudin, M., Wall, M., Wallis, J. M., Whiteley, M. N., Willey, D., Williams, L., Williams, S., Williamson, H., Wilmer, T. E., Wilming, L., Wright, C. L., Hubbard, T., Bentley, D. R., Beck, S., Rogers, J., Shimizu, N., Minoshima, S., Kawasaki, K., Sasaki, T., Asakawa, S., Kudoh, J., Shintani, A., Shibuya, K., Yoshizaki, Y., Aoki, N., Mitsuyama, S., Roe, B. A., Chen, F., Chu, L., Crabtree, J., Deschamps, S., Do, A., Do, T., Dorman, A., Fang, F., Fu, Y., Hu, P., Hua, A., Kenton, S., Lai, H., Lao, H. I., Lewis, J., Lewis, S., Lin, S.-P., Loh, P., Malaj, E., Nguyen, T., Pan, H., Phan, S., Qi, S., Qian, Y., Ray, L., Ren, Q., Shaull, S., Sloan, D., Song, L., Wang, Q., Wang, Y., Wang, Z., White, J., Willingham, D., Wu, H., Yao, Z., Zhan, M., Zhang, G., Chissoe, S., Murray, J., Miller, N., Minx, P., Fulton, R., Johnson, D., Bemis, G., Bentley, D., Bradshaw, H., Bourne, S., Cordes, M., Du, Z., Fulton, L., Goela, D., Graves, T., Hawkins, J., Hinds, K., Kemp, K., Latreille, P., Layman, D., Ozersky, P., Rohlfing, T., Scheet, P., Walker, C., Wamsley, A., Wohldmann, P., Pepin, K., Nelson, J., Korf, I., Bedell, J. A., Hillier, L., Mardis, E., Waterston, R., Wilson, R., Emanuel, B. S., Shaikh, T., Kurahashi, H., Saitta, S., Budarf, M. L., McDermid, H. E., Johnson, A., Wong, A. C. C., Morrow, B. E., Edelmann, L., Kim, U. J., Shizuya, H., Simon, M. I., Dumanski, J. P., Peyrard, M., Kedra, D., Seroussi, E., Fransson, I., Tapia, I., Bruder, C. E., & O'Brien, K. P.
- Venue
- Nature
- Published
- 1999-12-02
- Volume
- 402
- Issue
- 6761
- Pages
- 489-495
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2949977409
- Cited by
- 1,157
- References
- 1
- FWCI
- 103.68
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: The DNA sequence of human chromosome 22. https://app.cochat.ai/papers/10.1038/990031
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- Dunham, I., Hunt, A. R., Collins, J. E., Bruskiewich, R., Beare, D. M., Clamp, M., Smink, L. J., Ainscough, R., Almeida, J. P., Babbage, A., Bagguley, C., Bailey, J., Barlow, K., Bates, K. N., Beasley, O., Bird, C. P., Blakey, S., Bridgeman, A. M., Buck, D., . . . O'Brien, K. P. (1999). The DNA sequence of human chromosome 22. Nature. https://doi.org/10.1038/990031
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