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Cited by 261

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Rate and Predictors of Early/Missed Colorectal Cancers After Colonoscopy in Manitoba: A Population-Based Study

Singh, Harminder, Nugent, Zoann, Demers, Alain A, Bernstein, Charles N·2010·American Journal of Gastroenterology

Abstract

OBJECTIVES: Many of the colorectal cancers (CRCs) diagnosed within 3 years after a colonoscopy are likely because of lesions missed on the initial colonoscopy. In this population-based study, we investigated the rate and predictors of CRCs diagnosed within 3 years of a colonoscopy. METHODS: We identified individuals 50-80 years of age diagnosed with CRC between 1992 and 2008 from the provincewide Manitoba Cancer Registry. Performance of colonoscopy and history of co-morbidities was determined by linkage to the provincial universal health care insurance provider's physician billing claims and hospital discharges databases. CRCs diagnosed within 6 months of a colonoscopy were categorized as detected CRCs and those 6-36 months after a colonoscopy as early/missed CRCs. Logistic regression analysis was performed to identify the patient, endoscopist, colonoscopy, and CRC factors associated with early/missed CRCs. RESULTS: Of the 4,883 CRCs included in the study, 388 (7.9%) were early/missed CRCs, with a range of 4.5% of rectum/rectosigmoid cancers in men to 14.4% of transverse colon/splenic flexure cancers in women. Independent risk factors associated with early/missed CRCs included prior colonoscopy, performance of index colonoscopy by family physicians, recent year of CRC diagnosis, and proximal site of CRC. CONCLUSIONS: This study suggests that approximately 1 in 13 CRCs may be an early/missed CRC, diagnosed after an index colonoscopy in usual clinical practice. Women are more likely to have early/missed CRC. It is unclear if this relates to differences in procedure difficulty, bowel preparation issues, or tumor biology between men and women.

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Metadata

Authors
Singh, H., Nugent, Z., Demers, A. A., & Bernstein, C. N.
Venue
American Journal of Gastroenterology
Published
2010-12
Volume
105
Issue
12
Pages
2588-2596
ISSN
0002-9270 (ISSN-L)
OpenAlex
W2066639061
Cited by
261
References
25
FWCI
9.40
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Rate and Predictors of Early/Missed Colorectal Cancers After Colonoscopy in Manitoba: A Population-Based Study. https://app.cochat.ai/papers/10.1038/ajg.2010.390
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Singh, H., Nugent, Z., Demers, A. A., & Bernstein, C. N. (2010). Rate and Predictors of Early/Missed Colorectal Cancers After Colonoscopy in Manitoba: A Population-Based Study. American Journal of Gastroenterology. https://doi.org/10.1038/ajg.2010.390

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