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Photodynamic destruction of human bladder carcinoma
Open accessAbstract
Eleven human bladder carcinomata of different degrees of differentiation were implanted in mice immunosuppressed by thymectomy, anti-thymocyte serum and x-rays. Seven carcinomata grew well and one poorly and 3 produced mainly fibrous nodules in the mice. Normal human bladder tissues were grown from 4 other patients. The administration of a haematoporphyrin derivative (HpD), followed 24 h later by exposure to white light, caused marked destruction of tumours but little or none of normal bladder tissues. HpD or light alone caused no damage to tumours or normal tissues. It is suggested that photodynamic therapy may be applicable in the treatment of superficial transitional cell carcinoma of the bladder.
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Cited by
5‐Aminolevulinic Acid Derivatives in Photomedicine: Characteristics, Application and Perspectives
Fotinos, N., Campo, M. A., Popowycz, F., Gurny, R., & Lange, N. (2006) · Photochemistry and Photobiology · doi:10.1562/2006-02-03-ir-794 · Cited by 238
Metadata
- Authors
- Kelly, J. F., Snell, M. E., & Berenbaum, M. C.
- Venue
- British Journal of Cancer
- Published
- 1975-02
- Volume
- 31
- Issue
- 2
- Pages
- 237-244
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- OpenAlex
- W2018385435
- Cited by
- 246
- References
- 0
- FWCI
- 12.97
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kelly, J. F., Snell, M. E., & Berenbaum, M. C. (1975). Photodynamic destruction of human bladder carcinoma. British Journal of Cancer. https://doi.org/10.1038/bjc.1975.30
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
