Increasing incidence of adenocarcinoma of the gastric cardia and adjacent sites
Open accessAbstract
Data in a regional cancer registry covering a population of 5 million and with an efficiency of registration of over 95% have been used to examine incidence trends in oesophageal and gastric carcinoma. In the West Midlands Region of the UK, during the period 1962 to 1981 the age standardised incidence of gastric carcinoma decreased by 20%. However, an analysis by both histological type and detailed site reveals that while the incidence of distal lesions is diminishing, the incidence of adenocarcinoma of the oesophagus and cardia is increasing. The proximal and distal lesions also exhibit marked differences in social class distribution and sex ratio. The results strongly suggest that the aetiological factors involved for cardia and adjoining sites are different from those for pyloric antrum.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Incidence rates in cancers of the gastric cardia rose from the 1960s in the United Kingdom and the United States but appear to have leveled off in recent decades in the United States, Sweden, and the Netherlands.
“Incidence rates in cancers of the gastric cardia rose from the 1960s in the United Kingdom 114 and the United States 115 but appear to have leveled off in recent decades in the United States, 116 Sweden, 117 and the Netherlands.118”
From Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. (2024) · cites this paper as [114]
The Results (p. 441) report a significant increase in gastric-cardia cancer incidence from 1962–66 through 1977–81. The Methods describe data from the West Midlands Regional Cancer Registry, so the paper supports a rise in a UK region, not necessarily across the United Kingdom. Citation 114 is attached to the UK trend; the later claims about other countries are attributed to other citations. (LLM, conf=0.82)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 6 · Cited by 381
- Authors
- Powell, J., & McConkey, C.
- Affiliations
- Queen Elizabeth Hospital Birmingham (GB)
- ORCID
- Powell, J
- Venue
- British Journal of Cancer
- Published
- 1990-09
- Volume
- 62
- Issue
- 3
- Pages
- 440-443
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- PMC
- PMC1971432
- OpenAlex
- W1974541194
- Cited by
- 381
- References
- 6
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 5 · 2022: 5 · 2021: 5 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 7 · 2016: 5 · 2015: 4 · 2014: 12 · 2013: 5 · 2012: 8
- FWCI
- 14.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- British Journal of Cancer (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Gastric Cancer Management and Outcomes
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Health Sciences › Medicine › Surgery › Esophageal Cancer Research and Treatment
- Keywords
- gastric cardia cancer, esophageal adenocarcinoma, gastric adenocarcinoma, incidence trends, regional cancer registry, histological subtypes, sex ratio, etiology, West Midlands
- MeSH terms
- Adenocarcinoma, Carcinoma, Squamous Cell, Cardia, Deglutition Disorders, England, Esophageal Neoplasms, Female, Humans, Male, Pyloric Antrum, Social Class, Stomach Neoplasms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
