The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Symptoms at presentation for treatment in patients with lung cancer: implications for the evaluation of palliative treatment
Open accessAbstract
The ten most frequently reported pretreatment symptoms on the Rotterdam Symptom Checklist, which was completed by more than 650 patients entering two MRC Lung Cancer Working Party multicentre randomised trials, included general symptoms (tiredness, lack of appetite) and psychological distress (worry, anxiety) in addition to disease-related chest symptoms (cough, shortness of breath). Although the number and severity of symptoms increased with worsening performance status, the commonest symptoms were found to be virtually the same for patients with small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC), and for different grades of performance status. Women with NSCLC reported more psychological symptoms than males, but this difference was much less evident in patients with SCLC. Thus, in order to assess fully the benefit of palliative treatments in patients with lung cancer, account must be taken of all symptoms at presentation, in addition to the traditionally recognised chest symptoms.
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“especially lung and gastrointestinal cancers which have a poor prognosis and high symptom profile (12, 13).”
From Coping in Patients With Incurable Lung and Gastrointestinal Cancers: A Validation Study of the Brief COPE (2017) · cites this paper as [12]
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Metadata
- Authors
- on behalf of the Medical Research Council (MRC) Lung Cancer Working Party, Hopwood, P., & Stephens, R.
- Affiliations
- The Christie Hospital (GB)
- ORCID
- Hopwood, P
- Venue
- British Journal of Cancer
- Published
- 1995-03
- Volume
- 71
- Issue
- 3
- Pages
- 633-636
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- PMC
- PMC2033650
- OpenAlex
- W81256119
- Cited by
- 192
- References
- 23
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 4 · 2018: 5 · 2017: 3 · 2016: 7 · 2015: 10 · 2014: 11 · 2013: 9 · 2012: 8
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- British Journal of Cancer (publishedVersion)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Lung Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Keywords
- lung cancer, palliative care, Rotterdam Symptom Checklist, performance status, small cell lung cancer, non-small cell lung cancer, psychological distress, fatigue, cough, dyspnea, sex differences, symptom assessment
- MeSH terms
- Adult, Aged, Aged, 80 and over, Carcinoma, Non-Small-Cell Lung, Evaluation Studies as Topic, Female, Humans, Lung Neoplasms, Male, Middle Aged, Palliative Care, Quality of Life, Sex Factors, Multicenter Studies as Topic, Randomized Controlled Trials as Topic, Carcinoma, Small Cell
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