Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells

Tai, W-T, Shiau, C-W, Chen, H-L, Liu, C-Y, Lin, C-S, Cheng, A-L, Chen, P-J, Chen, K-F·2013·Cell Death & Disease
DOI 10.1038/cddis.2013.18

Cited by (202)

Items 101–200 of 202

  1. Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation
    Chunxiao Li, Liting Xiong, Yuhan Yang, Ping Jiang, Junjie Wang, Mengyuan Li, Shuhua Wei, Suqing Tian, Yuexuan Wang, Mi Zhang et al. · 2025 · Molecular Cancer
  2. The role and mechanism of autophagy in sorafenib targeted cancer therapy
    Heqing Yi, Long Bin, Ye Xuemei, Linfa Li · 2016 · Critical Reviews in Oncology/Hematology
  3. Sorafenib effect on liver neoplastic changes in rats: more than a kinase inhibitor
    Nahla E. El‐Ashmawy, Eman G. Khedr, Hoda A. El‐Bahrawy, Eslam E. Abd El-Fattah · 2016 · Clinical and Experimental Medicine
  4. Targeting autophagy in liver cancer
    Pietro Di Fazio, Sami Matrood · 2018 · Translational Gastroenterology and Hepatology
  5. Nephrotoxicity of Anti-Angiogenic Therapies
    Margaux Van Wynsberghe, Joanne Flejeo, Hamza Sakhi, Mario Ollero, Dil Sahali, Hassan Izzedine, Carole Hénique · 2021 · Diagnostics
  6. Small Molecule Inhibitors for Hepatocellular Carcinoma: Advances and Challenges
    Monica A. Kamal, Yasmine M. Mandour, Mostafa K. Abd El‐Aziz, Ulrike Stein, Hend Mohamed El Tayebi · 2022 · Molecules
  7. Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells
    Tingting Shi, Hisakazu Iwama, Koji Fujita, Hideki Kobara, Noriko Nishiyama, Shintaro Fujihara, Yasuhiro Goda, Hirohito Yoneyama, Asahiro Morishita, Joji Tani et al. · 2021 · International Journal of Molecular Sciences
  8. Mechanisms of EGFR-TKI-Induced Apoptosis and Strategies Targeting Apoptosis in EGFR-Mutated Non-Small Cell Lung Cancer
    Shigetoshi Nishihara, Toshimitsu Yamaoka, Fumihiro Ishikawa, Kensuke Higuchi, Yuki Hasebe, Ryo Manabe, Yasunari Kishino, Sojiro Kusumoto, Koichi Andō, Yusuke Kuroda et al. · 2022 · Genes
  9. Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells.
    Consuelo Amantini, Maria Beatrice Morelli, Matteo Santoni, Alessandra Soriani, Claudio Cardinali, Valério Farfariello, Anna Maria Eleuteri, Laura Bonfili, Matteo Mozzicafreddo, Massimo Nabissi et al. · 2015 · Oncoscience
  10. STAT3 regulates 5‐Fu resistance in human colorectal cancer cells by promoting Mcl‐1–dependent cytoprotective autophagy
    Yuanyi Yue, Qiang Zhang, Xueqing Wang, Zhengrong Sun · 2023 · Cancer Science
  11. Autophagy controls mesenchymal stem cell therapy in psychological stress colitis mice
    Jun Tian, Xiaoxing Kou, Runci Wang, Huan Jing, Chider Chen, Jianxia Tang, Xueli Mao, Bingjiao Zhao, Xi Wei, Songtao Shi · 2020 · Autophagy
  12. Treatment with metformin and sorafenib alleviates endometrial hyperplasia in polycystic ovary syndrome by promoting apoptosis via synergically regulating autophagy
    Qianqing Wang, Xiangcui Guo, Li Li, Zhi‐hui Gao, Mei Ji · 2019 · Journal of Cellular Physiology
  13. Vanillic Acid Improves Comorbidity of Cancer and Obesity through STAT3 Regulation in High-Fat-Diet-Induced Obese and B16BL6 Melanoma-Injected Mice
    Jinbong Park, Seon Yeon Cho, JongWook Kang, Woo Yong Park, Sujin Lee, Yunu Jung, Min-Woo Kang, Hyun Jeong Kwak, Jae‐Young Um · 2020 · Biomolecules
  14. Autophagy: A novel therapeutic target for hepatocarcinoma (Review)
    Zhanggui Wang, Weidong Han, Xinbing Sui, Yong Fang, Hongming Pan · 2014 · Oncology Letters
  15. Toxoplasma gondii induces autophagy and apoptosis in human umbilical cord mesenchymal stem cells via downregulation of Mcl−1
    Jiaqi Chu, Kaipeng Jing, Xiang Gao, Peng Li, Rui Huang, Yanru Niu, Shouquan Yan, Junchao Kong, Caiyuan Yu, Ge Shi et al. · 2017 · Cell Cycle
  16. Stat3‐Atg5 signal axis inducing autophagy to alleviate hepatic ischemia‐reperfusion injury
    Yu‐fang Han, Yanbing Zhao, Jun Li, Li Li, Yong‐gan Li, Shipeng Li, Zhong‐dong Li · 2017 · Journal of Cellular Biochemistry
  17. Autophagic cell death associated to Sorafenib in renal cell carcinoma is mediated through Akt inhibition in an ERK1/2 independent fashion
    Leticia Serrano‐Oviedo, Marta Ortega‐Muelas, Jesús García‐Cano, María Llanos Valero, Francisco J. Cimas, Raquel Pascual‐Serra, Diego M. Fernández‐Aroca, Olga Roche, María José Ruiz‐Hidalgo, Borja Belandia et al. · 2018 · PLoS ONE
  18. The MicroRNA-Based Strategies to Combat Cancer Chemoresistance via Regulating Autophagy
    Yuhe Lei, Lei Chen, Junshan Liu, Yinqin Zhong, Lijuan Deng · 2022 · Frontiers in Oncology
  19. Fibrinogen-Like Protein 1 Modulates Sorafenib Resistance in Human Hepatocellular Carcinoma Cells
    Yeonghoon Son, Na‐Rae Shin, Sung‐Ho Kim, Su-Cheol Park, Hae‐June Lee · 2021 · International Journal of Molecular Sciences
  20. New Insights into Therapy-Induced Progression of Cancer
    Polina V. Shnaider, Olga M. Ivanova, Irina K. Malyants, Ksenia S. Anufrieva, Ilya A. Semenov, Marat S. Pavlyukov, Maria A. Lagarkova, Vadim Markovich Govorun, Victoria О. Shender · 2020 · International Journal of Molecular Sciences
  21. MiR-21-5p promotes sorafenib resistance and hepatocellular carcinoma progression by regulating SIRT7 ubiquitination through USP24
    Zongqiang Hu, Yingpeng Zhao, Yuanyi Mang, Jiashun Zhu, Lu Yu, Li Li, Jianghua Ran · 2023 · Life Sciences
  22. RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells
    Jung-Chen Su, Ping‐Hui Tseng, Cheng-Yi Hsu, Wei‐Tien Tai, Jui‐Wen Huang, Ching-Huai Ko, Mai-Wei Lin, Chun‐Yu Liu, Kuen‐Feng Chen, Chung‐Wai Shiau · 2014 · Oncotarget
  23. Synergy with interferon-lambda 3 and sorafenib suppresses hepatocellular carcinoma proliferation
    Yuke Yan, Liang Wang, Jingjing He, Pengcheng Liu, Xi Lv, Yawu Zhang, Xiaodong Xu, Lingyi Zhang, Youcheng Zhang · 2017 · Biomedicine & Pharmacotherapy
  24. A comprehensive review of the relationship between autophagy and sorafenib-resistance in hepatocellular carcinoma: ferroptosis is noteworthy
    Kangnan Zhang, Qinghui Zhang, Rongrong Jia, Shihao Xiang, Ling Xu · 2023 · Frontiers in Cell and Developmental Biology
  25. Cytochrome B5 type A alleviates HCC metastasis via regulating STOML2 related autophagy and promoting sensitivity to ruxolitinib
    Hongrui Guo, Shuhang Liang, Yan Wang, Shuo Zhou, Dalong Yin, Shugeng Zhang, Jizhou Wang, Dehai Wu, Kun Ma, Yufeng Liu et al. · 2022 · Cell Death and Disease
  26. Global research status and frontiers on autophagy in hepatocellular carcinoma: a comprehensive bibliometric and visualized analysis
    Tao He, Jieyu Zou, Ke Sun, Juan Yang · 2024 · International Journal of Surgery
  27. Sorafenib Action in Hepatitis B Virus X–Activated Oncogenic Androgen Pathway in Liver through SHP-1
    Sheng-Han Wang, Shiou‐Hwei Yeh, Chung‐Wai Shiau, Kuen‐Feng Chen, Wei-Hsiang Lin, Ting‐Fen Tsai, Yuan‐Chi Teng, Ding‐Shinn Chen, Pei‐Jer Chen · 2015 · JNCI Journal of the National Cancer Institute
  28. Nonsteroidal Anti-inflammatory Drugs Sensitize CD44-Overexpressing Cancer Cells to Hsp90 Inhibitor Through Autophagy Activation
    Hyun‐Jung Moon, So‐Young Park, Su-Hoon Lee, Chi‐Dug Kang, Sun‐Hee Kim · 2019 · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  29. Autophagy and microRNA dysregulation in liver diseases
    Kyu Min Kim, Sang Geon Kim · 2014 · Archives of Pharmacal Research
  30. Molecular mechanisms of autophagy and implications in liver diseases
    Yuankai Wu, Hayden Weng Siong Tan, Jin-Yi Lin, Han‐Ming Shen, Haihe Wang, Guang Xiu Lu · 2023 · Liver Research
  31. FTY 720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib‐mediated cytotoxicity
    Dilruba Ahmed, Petra J. de Verdier, Charlotta Ryk, Oscar Lunqe, Per I Stal, Jenny Flygare · 2015 · Pharmacology Research & Perspectives
  32. Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
    R. Santarelli, M. Granato, A. Faggioni, M. Cirone · 2015 · Journal of Immunological Research
  33. Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
    Sucharat Tungsukruthai, Onrapak Reamtong, Sittiruk Roytrakul, Suchada Sukrong, Chanida Vinayanwattikun, Pithi Chanvorachote B · 2021 · Antioxidants
  34. Amygdalin promotes the activity of T cells to suppress the progression of HBV-related hepatocellular carcinoma via the JAK2/STAT3 signaling pathway
    Ruoyu Wang, Dong Zhang, Kewei Sun, Jianping Peng, Wenfang Zhu, Sihan Yin, Dan Tang, Yunan Wu · 2021 · BMC Infectious Diseases
  35. Phosphorylation of STAT3 at Tyr705 contributes to TFEB-mediated autophagy-lysosomal pathway dysfunction and leads to ischemic injury in rats
    Yueyang Liu, Xiaohang Che, Xiang‐Nan Yu, Hanxiao Shang, Peirui Cui, Xiaoxiao Fu, Xianda Lu, Yuhuan Liu, Chunfu Wu, Jingyu Yang · 2023 · Cellular and Molecular Life Sciences
  36. Dual Targeting of Sorafenib-Resistant HCC-Derived Cancer Stem Cells
    Ritu Shrestha, Kim R. Bridle, Lu Cao, Dorothy H. Crawford, Aparna Jayachandran · 2021 · Current Oncology
  37. Modulation of the Autophagy-Lysosomal Pathway in Hepatocellular Carcinoma Using Small Molecules
    Yu Geon Lee, Tae–Il Jeon · 2020 · Molecules
  38. VDAC2 and Bak scarcity in liver mitochondria enables targeting hepatocarcinoma while sparing hepatocytes
    Shamim Naghdi, Piyush Mishra, Soumya Sinha Roy, David Weaver, Ludivine Walter, Erika Davies, Anil Noronha Antony, Xuena Lin, Gisela Moehren, Mark A. Feitelson et al. · 2025 · Nature Communications
  39. Sorafenib prevents the proliferation and induces the apoptosis of liver cancer cells by regulating autophagy and hypoxia-inducible factor-1
    Qingzhuang Yang, Lianghui Gao, Xiaolong Huang, Jie Weng, Youke Chen, Shibu Lin, Qiushi Yin · 2021 · Experimental and Therapeutic Medicine
  40. miR-23b-3p Modulating Cytoprotective Autophagy and Glutamine Addiction in Sorafenib Resistant HepG2, a Hepatocellular Carcinoma Cell Line
    Ramanpreet Kaur, Shruthi Kanthaje, Sunil Taneja, Radha Krishan Dhiman, Anuradha Chakraborti · 2022 · Genes
  41. Sensitization of multidrug-resistant cancer cells to Hsp90 inhibitors by NSAIDs-induced apoptotic and autophagic cell death
    Hyun‐Jung Moon, Hak-Bong Kim, Su-Hoon Lee, So Eun Jeun, Chi‐Dug Kang, Sun‐Hee Kim · 2018 · Oncotarget
  42. Pharmacological Targeting of Ferroptosis in Cancer Treatment
    Amaneh Mohammadi Roushandeh, Mehryar Habibi Roudkenar, Mehdi Rabiee Valashedi, Amirsadegh Nikoo, Nima Najafi-Ghalehlou, Kazuo Tomita, Yoshikazu Kuwahara, Tomoaki Sato · 2021 · Current Cancer Drug Targets
  43. Sam68 promotes osteogenic differentiation of aortic valvular interstitial cells by TNF-α/STAT3/autophagy axis
    Xing Liu, Q. Zheng, Kan Wang, Jin Luo, Zhijie Wang, Hua-Dong Li, Zong-Tao Liu, Nianguo Dong, Jia-Wei Shi · 2023 · Journal of cell communication and signaling
  44. CircRNA LOC729852 promotes bladder cancer progression by regulating macrophage polarization and recruitment via the miR ‐769‐5p/ IL ‐10 axis
    Changming Dong, Pengyu Hui, Zhengqi Wu, Jianfeng Li, Xiaojun Man · 2024 · Journal of Cellular and Molecular Medicine
  45. Aberrant expression of p-STAT3 in peripheral blood CD4+ and CD8+ T cells related to hepatocellular carcinoma development
    Xu Wang, WENBIN XIN, Hua Zhang, Fengmei Zhang, MEILAN GAO, Lingling Yuan, Xiaoyan Xu, Xuemei Hu, Mingdong Zhao · 2014 · Molecular Medicine Reports
  46. Autophagy activity in cholangiocarcinoma is associated with anatomical localization of the tumor
    Gábor Lendvai, Tímea Szekerczés, Ildikó Illyés, Milán Csengeri, Krisztina Schlachter, Erzsébet Szabó, Gábor Lotz, András Kiss, Katalin Borka, Zsuzsa Schaff · 2021 · PLoS ONE
  47. RASSF6-mediated inhibition of Mcl-1 through JNK activation improves the anti-tumor effects of sorafenib in renal cell carcinoma
    Yingying Liang, Xubin Deng, Li-Si Zeng, Xiantao Lin, Xunfan Shao, Bin Wang, Zhi-Wen Mo, Yawei Yuan · 2018 · Cancer Letters
  48. Natural 2′,4-Dihydroxy-4′,6′-dimethoxy Chalcone Isolated from Chromolaena tacotana Inhibits Breast Cancer Cell Growth through Autophagy and Mitochondrial Apoptosis
    Gina Méndez-Callejas, Marco Piñeros-Avila, Crispín Astolfo Celis, Rubén Torrenegra, Anderson Espinosa-Benitez, Roberto Pestana-Nobles, Juvenal Yosa-Reyes · 2024 · Plants
  49. Pan-class I PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53
    Anja Müller, Bernhard F. Gillissen, Antje Richter, Anja M. Richter, Cindrilla Chumduri, Peter T. Daniel, Christian Wilfried Scholz · 2018 · Cell Death and Disease
  50. Hepatocellular Carcinoma
    Bubu A. Banini, Lewis Rowland Roberts · 2015 · Springer eBooks
  51. Nintedanib Induces the Autophagy-Dependent Death of Gastric Cancer Cells by Inhibiting the STAT3/Beclin1 Pathway
    Hui Zhu, Min-Ming Xia, Ke-Hui Tong, Wenbiao Duan · 2022 · Digestive Diseases and Sciences
  52. Is Autophagy Targeting a Valid Adjuvant Strategy in Conjunction with Tyrosine Kinase Inhibitors?
    Ahmed M. Elshazly, Jingwen Xu, Nebras Y. Melhem, Alsayed Abdulnaby, Aya A. Elzahed, Tareq Saleh, David A. Gewirtz · 2024 · Cancers
  53. St. John’s Wort Suppresses Growth in Triple-Negative Breast Cancer Cell Line MDA-MB-231 by Inducing Prodeath Autophagy and Apoptosis
    Mikyoung You, Young-Hyun Lee, Hwa-Jin Kim, Ji Hyun Kook, Hyeon‐A Kim · 2020 · Nutrients
  54. Autophagy Modulation and Its Implications on Glioblastoma Treatment
    Johnny Chen, Andrea Salinas, Maximiliano Arath Morales, Xiaoqian Fang · 2023 · Current Issues in Molecular Biology
  55. Beclin-1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK-ES-1 cells via inhibition of MMP-9
    Conglin Ye, Xiaolong Yu, Xuqiang Liu, Ping Zhan, Tao Nie, Runsheng Guo, Hucheng Liu, Min Dai, Bin Zhang · 2017 · Oncology Letters
  56. Opportunities and challenges of co‑targeting epidermal growth factor receptor and autophagy signaling in non‑small cell lung cancer (Review)
    Xiaoju Wang, Wenxin Li, Ni Zhang, Xiaoli Zheng, Jing Zhao · 2019 · Oncology Letters
  57. Mechanistic Insights about Sorafenib-, Valproic Acid- and Metformin-Induced Cell Death in Hepatocellular Carcinoma
    Edgar Xchel Franco-Juárez, Vianey González-Villasana, María Elena Camacho-Moll, Luisa Rendón-Garlant, Patricia Nefertari Ramírez-Flores, Beatriz Silva-Ramírez, Katia Peñuelas-Urquides, Ethel Daniela Cabello-Ruiz, Fabiola Castorena‐Torres, Mario Bermúdez de León · 2024 · International Journal of Molecular Sciences
  58. RETRACTED: Furowanin A-induced autophagy alleviates apoptosis and promotes cell cycle arrest via inactivation STAT3/Mcl-1 axis in colorectal cancer
    Zhao Ma, Xuebin Bao, Junbao Gu · 2018 · Life Sciences · Retracted
  59. The up-regulation of P62 levels is associated with resistance of sorafenib in hepatocarcinoma cells.
    Junping Pan, Chenglin Lu, Jun Wang, Yafu Wu, Xiaolei Shi, Yitao Ding · 2019 · Europe PMC (PubMed Central)
  60. Identification of a prognostic signature of nine metabolism-related genes for hepatocellular carcinoma
    Chaozhi Tang, Jiakang Ma, Xiuli Liu, Zhengchun Liu · 2020 · PeerJ
  61. In desmoid-type fibromatosis cells sorafenib induces ferroptosis and apoptosis, which are enhanced by autophagy inhibition
    Anne‐Rose W. Schut, Anne L. M. Vriends, Andrea Sacchetti, Milea J. M. Timbergen, Benjamin Aaron Alman, Mushriq Al‐Jazrawe, Dirk Jan Grünhagen, Cornelis Kees Verhoef, Stefan Sleijfer, Erik A.C. Wiemer · 2022 · European Journal of Surgical Oncology
  62. The combination of lonafarnib and sorafenib induces cyclin D1 degradation via ATG3-mediated autophagic flux in hepatocellular carcinoma cells
    Jialiang Wang, Huan Jun Wei, Yanlin Huang, Dongmei Chen, Guofen Zeng, Yifan Lian, Yuehua Huang · 2019 · Aging
  63. Dovitinib Triggers Apoptosis and Autophagic Cell Death by Targeting SHP-1/p-STAT3 Signaling in Human Breast Cancers
    Yi‐Han Chiu, Yi‐Yen Lee, Kuo‐Chin Huang, Cheng-Chi Liu, Chen‐Si Lin · 2019 · Journal of Oncology
  64. Effects of Sorafenib and Arsenic Trioxide on U937 and KG-1 Cell Lines: Apoptosis or Autophagy?
    Atousa Haghi, Mahdieh Salami, Mahnaz Mohammadi Kian, Mohsen Nikbakht, Saeed Mohammadi, Bahram Chahardouli, Shahrbanoo Rostami, Kianoosh Malekzadeh · 2020 · PubMed
  65. A Novel Drug Resistance Mechanism: Genetic Loss of Xeroderma Pigmentosum Complementation Group C (XPC) Enhances Glycolysis-Mediated Drug Resistance in DLD-1 Colon Cancer Cells
    Yu Kyeong Han, Yuan Qing Qu, Simon Wing Fai Mok, Juan Chen, Cheng Lai Xia, Hu Qiang He, Zheng Li, Wei Zhang, Cong Ling Qiu, Liang Liu et al. · 2019 · Frontiers in Pharmacology
  66. An overview of autophagy inhibition as a potential clinical strategy in cancer therapy
    Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Aya A. Elzahed, David A. Gewirtz · 2025 · Molecular Pharmacology
  67. Inhibition of anti-apoptotic Bcl-2 family members promotes synergistic cell death with ER stress inducers by disrupting autophagy in glioblastoma
    Tianyi Huang, Satoshi Takagi, Sumie Koike, Ryohei Katayama · 2025 · Cell Death Discovery
  68. Sorafenib resistance and autophagy in hepatocellular carcinoma: A concealed threat
    Biju Pottakkat, Kandasamy Ashokachakkaravarthy · 2019 · Journal of Cancer Research and Practice
  69. Bilirubin inhibits the anticancer activity of sorafenib by blocking MCL-1 degradation in hepatocellular carcinoma cells
    Leyi Yao, Qian Zhao, Yan Ding, Ziying Lei, Yali Hao, Jinghong Chen, Qian Xue, Xiaofen Li, Qingtian Huang, Daolin Tang et al. · 2022 · Cancer Biology and Medicine
  70. Targeting Oncogene-Induced Autophagy: A New Approach in Cancer Therapy?
    Fuquan Zhang, Jit Kong Cheong · 2013 · Journal of Cancer Research
  71. Tumor-suppressing effects of autophagy on hepatocellular carcinoma
    Lijun Pang, Kai Liu · 2018 · Liver Research
  72. Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy
    Yuexiao Tang, Ke Chen, Xiaorui Luan, Jinyan Zhang, Rongrong Liu, Xiaoxiao Zheng, Shangzhi Xie, Haiping Ke, Xianning Zhang, Wei Chen · 2020 · International Journal of Oncology
  73. [Corrigendum] Beclin‑1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK‑ES‑1 cells via inhibition of MMP‑9
    Conglin Ye, Xiaolong Yu, Xuqiang Liu, Ping Zhan, Tao Nie, Runsheng Guo, Hucheng Liu, Min Dai, Bin Zhang · 2020 · Oncology Letters
  74. Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma
    Tingyu Liu, Xin Yue, Xue Chen, Ru Yan, Chong Wu, Yunzhi Li, Xianzhang Bu, Hui Han, Ranyi Liu · 2024 · Cellular Oncology
  75. The mtDNA-STING pathway plays an important role in both navitoclax- and S63845-induced autophagy and enhances cell death
    Jia Jia, Mengqing Li, Yunjian Li, Jun Xiao, Haiming Dai · 2023 · Cell Biology and Toxicology
  76. Role of the Beclin 1 Network in the Cross-Regulation Between Autophagy and Apoptosis
    Yangchun Xie, Rui Kang, Daolin Tang · 2016 · Elsevier eBooks
  77. Targeting autophagy in dysfunctional tumor vasculature
    Qian Lin, Beichen Cai, Ruonan Ke, Xuejun Ni, Xiaofen Wan, Lu Chen, Tao Huang, Xiuying Shan, Biao Wang · 2025 · iScience
  78. Anti-Cancer Strategy Based on Changes in the Role of Autophagy Depending on the Survival Environment and Tumorigenesis Stages
    Michael Lee, Hye‐Gyo Kim · 2024 · Molecules
  79. Regulation of autophagy and cellular signaling through non-histone protein methylation
    Yongfen Bao, Yaoyao Ma, Wentao Huang, Yujie Bai, Siying Gao, Luyao Xiu, Yuyang Xie, Xinrong Wan, Shigang Shan, Chao Chen et al. · 2024 · International Journal of Biological Macromolecules
  80. The potential anticancer effect of bee venom in combination with sorafenib against HepG2 cell lines via induction of apoptosis and autophagy candidate genes
    Sara A. Nusair, Gehan Galal, Sara M. Radwan · 2024 · Egyptian Journal of Medical Human Genetics
  81. Substituted 2-hydroxy-N-(arylalkyl)benzamide sensitizes cancer cells to metabolic stress by disrupting actin cytoskeleton and inhibiting autophagic flux
    Gabriela Páchniková, Stjepan Uldrijan, Aleš Imramovský, Vladimı́r Kryštof, Iva Slaninová · 2016 · Toxicology in Vitro
  82. Antrocinol-mediated downregulation of ATG5 induces autophagy-dependent cell death and activates the unfolded protein response through PERK/CHOP signaling in lenvatinib-resistant hepatocellular carcinoma cells
    Shiue‐Wei Lai, Yi‐Chiao Cheng, Ming‐Shou Hsieh, Kuang‐Tai Kuo, Vijesh Kumar Yadav, Yew‐Min Tzeng, Chi‐Tai Yeh, Tung-Yao Tsai · 2025 · European Journal of Pharmacology
  83. Milk-derived extracellular vesicles enhanced Sorafenib's therapeutic response on hepatocellular carcinoma cells
    Mahsa Salehi, Babak Negahdari, Mahdieh Hashemi, Homeyra Seydi, Sareh Salarinejad, Abbas Piryaei, Alimohamad Moradi, Ali Zarrabi, Faezeh Shekari, Massoud Vosough · 2026 · Journal of Drug Delivery Science and Technology
  84. Critical role of miR-21/exosomal miR-21 in autophagy pathway
    Mohamed Jamal Saadh, Morug Salih Mahdi, Omer Qutaiba B. Allela, Tuqa S. Alazzawi, Mohammed Ubaid, Nodir Rakhimov, Zainab H. Athab, Pushpamala Ramaiah, Lathamangeswari Chinnasamy, Fahad Alsaikhan et al. · 2024 · Pathology - Research and Practice
  85. Anti-cancer effect of Cissus quadrangularis on human glioblastoma cells
    Benxu Cheng, Yunlin Wei, Lili Guerra, Rozena Shirvani-Arani, Santiago Balderas, Laura Valdez, Andrew T. C. Tsin, Xiaoqian Fang · 2023 · RPS Pharmacy and Pharmacology Reports
  86. Pharmacological Targeting of Ferroptosis in Cancer Treatment
    Mohammad Altaf Khan, Trilochan Satapathy, Kalpana Sen, Shailesh Sahu, Bharti Pradhan, Ayushi Gupta, Abinash Satapathy, Ansuman Satapathy · 2024 · Journal of Drug Delivery and Therapeutics
  87. SHBs Mitigates Sorafenib‐Induced Apoptosis in Hepatocellular Carcinoma via Activation of RAF1 / MEK / ERK Signaling Pathway
    Shuxiang Wu, Yuxiang Hong, Hang Li, Meng-Xian Lin, Xiaohuang Lin, Xu Lin, Xu Lin · 2025 · Cancer Science
  88. STAT3 mediates cancer stem‐like tumorsphere formation and PD‐L1 expression to contribute radioresistance in HBV ‐positive hepatocellular carcinoma
    Ai‐Sheng Ho, Chun‐Chia Cheng, Cheng‐Liang Peng, Zong‐Lin Sie, Chun Yeh, Shou‐Dong Lee · 2024 · Advances in digestive medicine
  89. Design, synthesis, and biological evaluation of KA7, a novel quinolone-based sorafenib analogue with potent anticancer and immunomodulatory activities
    Duaa Azmi Abuarqoub, Ahmed Al‐Sheikh, Marwa Mohammad, Hana'a Khalaf, Nour Albaz, Ali Hmedat · 2025 · RSC Advances
  90. Differential Induction of Autophagy and Mitochondrial Apoptosis by 2′, 4-Dihydroxy-4′, 6′-Dimethoxy Chalcone Isolated from Chromolaena tacotana, in Breast Cancer Cells
    Gina Méndez-Callejas, Marco Piñeros-Avila, Crispín Astolfo Celis, Rubén Torrenegra, Anderson Espinosa-Benitez, Roberto Pestana-Nobles, Juvenal Yosa-Reyes · 2023 · Preprints.org
  91. EGFRvIII : molecular insights and therapeutic potential
    Barry Jutten · 2014
  92. Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs
    Alex Xing Fah Wong · 2018
  93. Sorafenib
    Giuseppe Tridente · 2017 · Elsevier eBooks
  94. LncRNA CRNDE decreases the sensitivity of sorafenib in HCC cells via promoting ATG4B-mediated autophagy
    Lingxi Chen, Liangbo Sun, Xufang Dai, Tao Li, Xiaojing Yan, Yueting Zhang, Hanxi Xiao, Xiaodong Shen, Gang Huang, Wei Dong Xiang et al. · 2021 · Research Square
  95. Fiddle Songs and Banjo Songs: A Description Index
    Gilbert Wayne Howard · 1981 · TopSCHOLAR (Western Kentucky University)
  96. Aging
    Eugenia Morselli, Alfredo Criollo · 2016 · Springer eBooks
  97. Research Progress on the Mechanisms of Autophagy in Hepatocellular Carcinoma
    C S Zhu · 2024 · Highlights in Science Engineering and Technology
  98. Étude du récepteur SLAMF3 : mécanismes et stratégies thérapeutiques dans les cancers solides
    Grégory Fouquet · 2018
  99. Contrôle du développement et de la progression du carcinome hépatocellulaire par l’autophagie des macrophages : rôle du micro-environnement immunitaire
    Anthony Deust · 2020
  100. Une nouvelle stratégie thérapeutique pour prolonger la réponse du cancer bronchique aux inhibiteurs d’EGFR en prévenant l’émergence des cellules résistantes
    Lisa Brunet · 2021 · theses.fr (ABES)