Cited by 30Statistical Methods in Clinical TrialsPharmaceutical studies and practicesSimulation Techniques and Applications

Impact of Modeling and Simulation: Myth or Fact?

Allerheiligen, S R B·2014·Clinical Pharmacology & Therapeutics

Integrity signals

Registry

Crossref · 10.1038/clpt.2014.122

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

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Claims other papers make about this one

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References 5 · Cited by 30

Authors
Allerheiligen, S. R. B.
Affiliations
Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
Corresponding author
Allerheiligen, S R B
Venue
Clinical Pharmacology & Therapeutics
Publisher
Wiley
Published
2014-10
Volume
96
Issue
4
Pages
413-415
ISSN
  • 0009-9236 (ISSN-L)
  • 1532-6535
OpenAlex
W2012322080
Cited by
30
References
5
Citations by year
2026: 1 · 2025: 1 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 3 · 2019: 3 · 2018: 5 · 2016: 2 · 2015: 3 · 2013: 1
FWCI
1.76
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Pharmacology & Therapeutics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmaceutical studies and practices
  • Social Sciences › Decision Sciences › Management Science and Operations Research › Simulation Techniques and Applications
Keywords
modeling and simulation, clinical pharmacology, drug development, predictive modeling, translational research
MeSH terms
Computer Simulation, Drug Industry, Pharmaceutical Preparations, Models, Biological, Models, Molecular, Pharmacokinetics, Drug Discovery, Drug-Related Side Effects and Adverse Reactions

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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