The search for better animal models of Alzheimer’s disease

Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

Claassen, J. A. H. R., Thijssen, D. H. J., Panerai, R. B., & Faraci, F. M. (2021) · Physiological Reviews · doi:10.1152/physrev.00022.2020 · Cited by 1,005

Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease.

Forner, S., Kawauchi, S., Balderrama-Gutierrez, G., Kramár, E. A., Matheos, D. P., Phan, J., Javonillo, D. I., Tran, K. M., Hingco, E., da Cunha, C., et al. (2021) · Scientific Data · doi:10.1038/s41597-021-01054-y · Cited by 501

Advances in CNS PET: the state-of-the-art for new imaging targets for pathophysiology and drug development

McCluskey, S. P., Plisson, C., Rabiner, E. A., & Howes, O. D. (2019) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-019-04488-0 · Cited by 127

Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia

Wang, P., Velagapudi, R., Kong, C., Rodriguiz, R. M., Wetsel, W. C., Yang, T., Berger, M., Gelbard, H. A., Colton, C. A., & Terrando, N. (2020) · Alzheimer s & Dementia · doi:10.1002/alz.12064 · Cited by 120

Human Brain Surrogates Research: The Onrushing Ethical Dilemma

Greely, H. T. (2020) · The American Journal of Bioethics · doi:10.1080/15265161.2020.1845853 · Cited by 117

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology

Baglietto‐Vargas, D., Forner, S., Cai, L., Martini, A. C., Trujillo‐Estrada, L., Swarup, V., Nguyen, M. M. T., Huynh, K. D., Javonillo, D. I., Tran, K. M., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22624-z · Cited by 120

Exploring the efficacy of natural products in alleviating Alzheimer’s disease

Singh, A., Deshpande, P., & Gogia, N. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.253509 · Cited by 111

A novel tau‐based rhesus monkey model of Alzheimer's pathogenesis

Beckman, D., Chakrabarty, P., Ott, S. P., Dao, A., Zhou, E., Janssen, W. G. M., Donis‐Cox, K., Muller, S., Kordower, J. H., & Morrison, J. H. (2021) · Alzheimer s & Dementia · doi:10.1002/alz.12318 · Cited by 112

Alzheimer’s disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?

Mullane, K., & Williams, M. J. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.113945 · Cited by 109

A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer’s Disease

Provensi, G., Carta, F., Nocentini, A., Supuran, C. T., Casamenti, F., Passani, M. B., & Fossati, S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20194724 · Cited by 104

Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research

Dennison, J. L., Ricciardi, N. R., Lohse, I., Volmar, C., & Wahlestedt, C. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201014 · Cited by 107

Challenges and Opportunities in Central Nervous System Drug Discovery

Danon, J. J., Reekie, T. A., & Kassiou, M. (2019) · Trends in Chemistry · doi:10.1016/j.trechm.2019.04.009 · Cited by 86

Behaviour Hallmarks in Alzheimer’s Disease 5xFAD Mouse Model

Pádua, M. S., Guil‐Guerrero, J. L., & Lopes, P. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126766 · Cited by 87

Modeling late-onset Alzheimer’s disease neuropathology via direct neuronal reprogramming

Sun, Z., Kwon, J.-S., Ren, Y., Chen, S., Walker, C. K., Lu, X., Cates, K., Karahan, H., Sviben, S., Fitzpatrick, J. A. J., et al. (2024) · Science · doi:10.1126/science.adl2992 · Cited by 77

A Review of the Current Mammalian Models of Alzheimer’s Disease and Challenges That Need to Be Overcome

Mckean, N. E., Handley, R. R., & Snell, R. G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222313168 · Cited by 81

Insights into Computational Drug Repurposing for Neurodegenerative Disease

Paranjpe, M. D., Taubes, A. L., & Sirota, M. (2019) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2019.06.003 · Cited by 72

Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aβ oligomers?

Fantini, J., Chahinian, H., & Yahi, N. (2020) · Protein Science · doi:10.1002/pro.3906 · Cited by 63

Studies of aging nonhuman primates illuminate the etiology of early‐stage Alzheimer's‐like neuropathology: An evolutionary perspective

Arnsten, A. F. T., Datta, D., & Preuss, T. M. (2021) · American Journal of Primatology · doi:10.1002/ajp.23254 · Cited by 66

Mechanisms Underlying Brain Aging Under Normal and Pathological Conditions

Jin, M., & Cai, S. (2022) · Neuroscience Bulletin · doi:10.1007/s12264-022-00969-9 · Cited by 61

Can mouse models mimic sporadic Alzheimer’s disease?

Humpel, C., & Foidl, B. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.266046 · Cited by 56

The rise to dominance of genetic model organisms and the decline of curiosity-driven organismal research

Farris, S. M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0243088 · Cited by 52

Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease

Zielinski, M., Reyes, F. S. P., Gremer, L., Schemmert, S., Frieg, B., Schäfer, L. U., Willuweit, A., Donner, L., Elvers, M., Nilsson, L. N. G., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01484-4 · Cited by 53

Renin-Angiotensin System and Alzheimer’s Disease Pathophysiology: From the Potential Interactions to Therapeutic Perspectives

Ribeiro, V. T., de Souza, L. C., & Silva, A. C. S. E. (2019) · Protein and Peptide Letters · doi:10.2174/0929866527666191230103739 · Cited by 50

Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer’s disease

Töpperwien, M., van der Meer, F., Stadelmann, C., & Salditt, T. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.116523 · Cited by 48

Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approachPreprint

Logsdon, B. A., Perumal, T. M., Swarup, V., Wang, M., Funk, C. C., Gaiteri, C., Allen, M., Wang, X., Dammer, E. B., Srivastava, G. P., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/510420 · Cited by 46

Current progress of cerebral organoids for modeling Alzheimer's disease origins and mechanisms

Sreenivasamurthy, S., Laul, M., Zhao, N., Kim, T., & Zhu, D. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10378 · Cited by 49

Pharmacological Interventions to Attenuate Alzheimer’s Disease Progression: The Story So Far

Bazzari, F. H., Abdallah, D. M., & El-Abhar, H. S. (2019) · Current Alzheimer Research · doi:10.2174/1567205016666190301111120 · Cited by 39

High-Fat Diets in Animal Models of Alzheimer’s Disease: How Can Eating Too Much Fat Increase Alzheimer’s Disease Risk?

Valentin‐Escalera, J., Leclerc, M., & Calon, F. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-230118 · Cited by 37

Inappropriate modeling of chronic and complex disorders: How to reconsider the approach in the context of predictive, preventive and personalized medicine, and translational medicine

Seifirad, S., & Haghpanah, V. (2019) · The EPMA Journal · doi:10.1007/s13167-019-00176-z · Cited by 35

Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease

García‐León, J. A., Cáceres-Palomo, L., Sánchez‐Mejías, E., Mejias‐Ortega, M., Nuñez‐Diaz, C., Fernandez-Valenzuela, J. J., Sanchez-Varo, R. M., Dávila, J. C., Vitórica, J., & Gutiérrez, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186867 · Cited by 35

Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease

Rizzo, S. J. S., Homanics, G. E., Schaeffer, D. J., Schaeffer, L. K. H., Park, J. E., Oluoch, J., Zhang, T., Haber, A., Seyfried, N. T., Paten, B., et al. (2023) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.12417 · Cited by 40

Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology

Choe, M. S., Yeo, H. C., Kim, J., Lee, J., Lee, H. J., Kim, H., Baek, K. M., Jung, N., Choi, M., & Lee, M. Y. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-03732-1 · Cited by 39

Surgery Performed Under Propofol Anesthesia Induces Cognitive Impairment and Amyloid Pathology in ApoE4 Knock-In Mouse Model

Kim, J. H., Jung, H., Lee, Y., & Sohn, J. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.658860 · Cited by 33

Genetically modified non-human primate models for research on neurodegenerative diseases

Pan, M.-T., 暨南大学粤港澳中枢神经再生研究院, 广., Zhang, H., Li, X., & Guo, X. (2024) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2023.197 · Cited by 36

Decay in Retinoic Acid Signaling in Varied Models of Alzheimer’s Disease and In-Vitro Test of Novel Retinoic Acid Receptor Ligands (RAR-Ms) to Regulate Protective Genes

Khatib, T., Chisholm, D. R., Whiting, A., Platt, B., & McCaffery, P. J. A. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190931 · Cited by 31

The first Antechinus reference genome provides a resource for investigating the genetic basis of semelparity and age-related neuropathologies

Brandies, P. A., Tang, S. S. K., Johnson, R., Hogg, C. J., & Belov, K. (2020) · Gigabyte · doi:10.46471/gigabyte.7 · Cited by 29

Is It the Twilight of BACE1 Inhibitors?

Hrabinova, M., Pejchal, J., Kucera, T., Jun, D., Schmidt, M., & Soukup, O. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200503023323 · Cited by 28

Animal and Cellular Models of Alzheimer’s Disease: Progress, Promise, and Future Approaches

Trujillo‐Estrada, L., Sánchez‐Mejías, E., Sanchez-Varo, R. M., García‐León, J. A., Nuñez‐Diaz, C., Dávila, J. C., Vitórica, J., LaFerla, F. M., Moreno‐González, I., Gutiérrez, A., et al. (2021) · The Neuroscientist · doi:10.1177/10738584211001753 · Cited by 30

The marmoset as an important primate model for longitudinal studies of neurocognitive aging

Rothwell, E. S., Freire‐Cobo, C., Varghese, M., Edwards, M. M., Janssen, W. G. M., Hof, P. R., & Agnès Lacreuse, A. (2021) · American Journal of Primatology · doi:10.1002/ajp.23271 · Cited by 27

Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer’s Disease

Ameen, A. O., Freude, K., & Aldana, B. I. (2022) · Biomedicines · doi:10.3390/biomedicines10112778 · Cited by 29

Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer’s disease

Cuní‐López, C., Stewart, R., Oikari, L. E., Nguyen, T. H., Roberts, T. L., Sun, Y., Guo, C. C., Lupton, M. K., White, A. R., & Quek, H. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03037-3 · Cited by 28

Alzheimer's Disease: Many Failed Trials, So Where Do We Go from Here?

Reiss, A. B., Glass, A. D., Wısnıewskı, T., Wolozin, B. L., Gomolin, I. H., Pinkhasov, A., Leon, J. D., & Stecker, M. M. (2020) · Journal of Investigative Medicine · doi:10.1136/jim-2020-001297 · Cited by 26

Alzheimer’s Disease, and Breast and Prostate Cancer Research: Translational Failures and the Importance to Monitor Outputs and Impact of Funded Research

Pistollato, F., Bernasconi, C., McCarthy, J., Campia, I., Desaintes, C., Wittwehr, C., Deceuninck, P., & Whelan, M. (2020) · Animals · doi:10.3390/ani10071194 · Cited by 25

Invasive and non-invasive therapies for Alzheimer’s disease and other amyloidosis

Pandey, G., & Ramakrishnan, V. (2020) · Biophysical Reviews · doi:10.1007/s12551-020-00752-y · Cited by 26

Synchronous nonmonotonic changes in functional connectivity and white matter integrity in a rat model of sporadic Alzheimer's disease

Tristão‐Pereira, C., Diao, Y., Yin, T., da Silva, A. R., Lanz, B., Pierzchała, K., Poitry‐Yamate, C., & Jelescu, I. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117498 · Cited by 24

Connecting vascular aging and frailty in Alzheimer’s disease

Sabbatinelli, J., Ramini, D., Giuliani, A., Recchioni, R., Spazzafumo, L., & Olivieri, F. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111444 · Cited by 23

Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans

Pretsch, D., Rollinger, J. M., Schmid, A., Genov, M., Wöhrer, T., Krenn, L., Moloney, M. G., Kasture, A. S., Hummel, T., & Pretsch, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-68561-7 · Cited by 23

Switching On/Off Amyloid Plaque Formation in Transgenic Animal Models of Alzheimer’s Disease

Kozin, S. A., Kechko, O. I., Adzhubei, A. A., Makarov, A. А., & Mitkevich, V. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010072 · Cited by 21

Human in vitro systems for examining synaptic function and plasticity in the brain

Lee, K., Park, T., Heppner, P. A., Schweder, P. M., Mee, E. W., Dragunow, M., & Montgomery, J. M. (2020) · Journal of Neurophysiology · doi:10.1152/jn.00411.2019 · Cited by 22

Brain Organoids: Tiny Mirrors of Human Neurodevelopment and Neurological Disorders

Yadav, A., Seth, B., & Chaturvedi, R. K. (2020) · The Neuroscientist · doi:10.1177/1073858420943192 · Cited by 19

Unraveling Alzheimer’s Disease Using Drosophila

Yeates, C. J., Sarkar, A., Kango‐Singh, M., & Singh, A. (2019) · Springer eBooks · doi:10.1007/978-981-13-2218-1_9 · Cited by 18

The Dilemma of Human Brain Surrogates: Scientific Opportunities, Ethical Concerns

Greely, H. T. (2020) · Springer eBooks · doi:10.1007/978-3-030-38840-9_18 · Cited by 18

Distinctive biophysical features of human cell-types: insights from studies of neurosurgically resected brain tissue

Chameh, H. M., Falby, M. R., Movahed, M., Arbabi, K., Rich, S., Zhang, L., Lefebvre, J., Tripathy, S. J., Pittà, M. D., & Valiante, T. A. (2023) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2023.1250834 · Cited by 15

Disembodied Brains

Evans, J. H. (2024) · doi:10.1093/oso/9780197750704.001.0001 · Cited by 16

Human stem cell transplantation models of Alzheimer’s disease

Ifediora, N., Canoll, P., & Hargus, G. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1354164 · Cited by 18

Pursuit of precision medicine: Systems biology approaches in Alzheimer's disease mouse models

Gurdon, B., & Kaczorowski, C. C. (2021) · Neurobiology of Disease · doi:10.1016/j.nbd.2021.105558 · Cited by 16

Epigenetic plasticity and redox regulation of neural stem cell state and fate

Tay, E. X. Y., Chia, K., & Ong, D. S. T. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.02.030 · Cited by 15

Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer’s disease at 12p12.1

Lee, B., Yao, X., Shen, L., & Initiative, A. D. N. (2022) · BMC Genomics · doi:10.1186/s12864-021-08269-8 · Cited by 13

Intrathecal amyloid‐beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's disease

Wakeman, D. R., Weed, M. R., Perez, S. E., Cline, E. N., Viola, K. L., Wilcox, K. C., Moddrelle, D. S., Nisbett, E. Z., Kurian, A., Bell, A., et al. (2022) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12800 · Cited by 18

Sowing the Seeds of Discovery: Tau-Propagation Models of Alzheimer’s Disease

Bell, B. J., Malvankar, M. M., Tallon, C., & Slusher, B. S. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00531 · Cited by 15

Systematic Review of the Preclinical Technology Readiness of Orthopedic Gene Therapy and Outlook for Clinical Translation

Wilkinson, P., Bozo, I. Y., Braxton, T., Just, P., Jones, E., Deev, R. V., Giannoudis, P. V., & Feichtinger, G. A. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.626315 · Cited by 15

Critical thinking of Alzheimer’s transgenic mouse model: current research and future perspective

Li, X., Quan, M., Wei, Y., Wang, W., Xu, L., Wang, Q., & Jia, J. (2023) · Science China Life Sciences · doi:10.1007/s11427-022-2357-x · Cited by 14

Utility of spontaneous animal models of Alzheimer’s disease in preclinical efficacy studies

Zeiss, C. J. (2020) · Cell and Tissue Research · doi:10.1007/s00441-020-03198-6 · Cited by 16

The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible

Cassotta, M. (2022) · ALTEX · doi:10.14573/altex.2203161 · Cited by 14

Characterizing dog cognitive aging using spontaneous problem-solving measures: development of a battery of tests from the Dog Aging Project

Hargrave, S. H., Bray, E. E., McGrath, S., Alexander, G. E., Block, T. A., Chao, N., Darvas, M., Douglas, L. E. L. C., Galante, J., Kennedy, B. S., et al. (2024) · GeroScience · doi:10.1007/s11357-024-01278-x · Cited by 13

The three sisters of fate: Genetics, pathophysiology and outcomes of animal models of neurodegenerative diseases

Klonarakis, M., Vos, M. D., Woo, E. K., Ralph, L. T., Thacker, J. S., & Gil‐Mohapel, J. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104541 · Cited by 14

Autologous skin-derived neural precursor cell therapy reverses canine Alzheimer dementia-like syndrome in a proof of concept veterinary trial

Valenzuela, M., Duncan, T., Abey, A. S., Johnson, A. J., Boulamatsis, C., Dalton, M. A., Jacobson, E. E., Brunel, L. M., Child, G., Simpson, D., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02933-w · Cited by 13

Nanotechnology Therapy for Alzheimer′s Disease Memory Impairment Attenuation

Ribarič, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031102 · Cited by 13

The search for anti‐oxytotic/ferroptotic compounds in the plant world

Soriano‐Castell, D., Liang, Z., Maher, P. A., & Currais, A. J. M. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15517 · Cited by 12

Sequence of Molecular Events in the Development of Alzheimer’s Disease: Cascade Interactions from Beta-Amyloid to Other Involved Proteins

Bagheri, S., Saboury, A. A., & Saso, L. (2024) · Cells · doi:10.3390/cells13151293 · Cited by 12

The etiology and prevention of early‐stage tau pathology in higher cortical circuits: Insights from aging rhesus macaques

Datta, D., & Arnsten, A. F. T. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.14477 · Cited by 11

Retinal Changes in Transgenic Mouse Models of Alzheimer’s Disease

Guo, L., Ravindran, N., Shamsher, E., Hill, D., & Cordeiro, M. F. (2021) · Current Alzheimer Research · doi:10.2174/1567205018666210414113634 · Cited by 13

In vivo validation of late‐onset Alzheimer's disease genetic risk factors

Sasner, M., Preuß, C., Pandey, R. S., Uyar, A., Garceau, D. T., Kotredes, K. P., Williams, H. M., Oblak, A. L., Lin, P. B., Perkins, B. M., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13840 · Cited by 13

Plasma proteomics and lipidomics facilitate elucidation of the link between Alzheimer's disease development and vessel wall fragility

Tokuoka, S. M., Hamano, F., Kobayashi, A., Adachi, S., Andou, T., Natsume, T., & Oda, Y. (2024) · Scientific Reports · doi:10.1038/s41598-024-71097-9 · Cited by 10

Uncovering the Oxidative Stress Mechanisms and Targets in Alzheimer’s Disease by Integrating Phenotypic Screening Data and Polypharmacology Networks

Zhou, M., Jiao, Q., Wu, Z., Li, W., Liu, G., Wang, R., & Tang, Y. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-220727 · Cited by 10

Modeling neurodegenerative diseases using non-human primates: advances and challenges

Li, B., He, D., Li, X., & Guo, X. (2022) · Ageing and Neurodegenerative Diseases · doi:10.20517/and.2022.14 · Cited by 11

Evaluation of Memantine in AAV-AD Rat: A Model of Late-Onset Alzheimer's Disease Predementia

Souchet, B., Audrain, M., Alves, S., Fol, R. R., Tada, S., Orefice, N. S., Potier, B., Dutar, P., Billard, J., Cartier, N., et al. (2022) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2021.67 · Cited by 9

Amyloid pathology and cognitive impairment in hAβ-KI and APPSAA-KI mouse models of Alzheimer's disease

Lü, W., Shue, F., Kurti, A., Jeevaratnam, S., Macyczko, J. R., Roy, B., Izhar, T., Wang, N., Bu, G., Kanekiyo, T., et al. (2024) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2024.10.005 · Cited by 9

Amyloid-β oligomers drive amyloid deposit and cascaded tau pathology of Alzheimer's disease in aged brains of non-human primates

He, Z., Zhang, W., Chen, P., Li, S., Tao, M., Yue, F., Hong, W., Feng, S., & Jing, N. (2025) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2025.02.007 · Cited by 9

A Comparison of Two-Dimensional and Three-Dimensional Techniques for Kinematic Analysis of the Sagittal Motion of Sheep Hindlimbs During Walking on a Treadmill

Diogo, C. C., Camassa, J. A. D. A., Fonseca, B., Maltez, L., Pereira, J. E., Filipe, V. M. D. J., Couto, P., Raimondo, S., Armada-da-Silva, P. A. S., Maurício, A. C., et al. (2021) · Frontiers in Veterinary Science · doi:10.3389/fvets.2021.545708 · Cited by 8

Emerging concepts towards a translational framework in Alzheimer’s disease

Cozachenco, D., Zimmer, E. R., & Lourenco, M. V. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105246 · Cited by 7

Facing the Complexity of Alzheimer's Disease

Dallemagne, P., & Rochais, C. (2019) · Future Medicinal Chemistry · doi:10.4155/fmc-2019-0310 · Cited by 7

First International Conference on Unconventional Animal Models of Alzheimer’s Disease and Aging

Cogram, P., Garduño, B. M., Ren, B., & Xu, X. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-249004 · Cited by 5

EBP1 potentiates amyloid β pathology by regulating γ-secretase

Kim, B.-S., Hwang, I., Ko, H. R., Kim, Y. K., Kim, H. J., Seo, S. W., Choi, Y., Lim, S., Kim, Y. K., Nie, S., et al. (2025) · Nature Aging · doi:10.1038/s43587-024-00790-1 · Cited by 4

Biomarkers and brains: situating dementia in the laboratory and in the memory clinic

Latimer, J., & Hillman, A. (2019) · New Genetics and Society · doi:10.1080/14636778.2019.1652804 · Cited by 5

Alzheimer-like pathology in the parietal cortex and hippocampus of aged donkeys

Malbon, A. J., Sordo, L., Wilson, L. A., Gunn-Moore, D. A., Paraschou, G., MacIntyre, N. R., Schwarz, T., McGorum, B. C., & HAHN, C. N. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.01.007 · Cited by 5

3D models of Alzheimer’s disease patient microglia recapitulate disease phenotype and show differential drug responses compared to 2DPreprint

Cuní‐López, C., Quek, H., Oikari, L. E., Stewart, R., Nguyen, T. H., Sun, Y., Guo, C. C., Lupton, M. K., & White, A. R. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.03.17.435758 · Cited by 4

Graph Theoretical Network Analysis and Pharmacoinformatics-Based Investigation of Bioactive Compounds from Semecarpus anacardium Linn. for Alzheimer’s Disease

Vijayalakshmi, M., Sundarapandian, V., Bharathi, V. S., Pavadai, P., Sundar, K., Kunjiappan, S., & Pandian, S. R. K. (2023) · Journal of Computational Biophysics and Chemistry · doi:10.1142/s2737416523410028 · Cited by 3

Animal Models of Alzheimer’s Disease Should Be Controlled for Roseolovirus

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